Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6KWW

HslU from Staphylococcus aureus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0008233	molecular_function	peptidase activity
A	0009376	cellular_component	HslUV protease complex
A	0016887	molecular_function	ATP hydrolysis activity
A	0036402	molecular_function	proteasome-activating activity
A	0043335	biological_process	protein unfolding
A	0051603	biological_process	proteolysis involved in protein catabolic process
A	1901800	biological_process	positive regulation of proteasomal protein catabolic process
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0008233	molecular_function	peptidase activity
B	0009376	cellular_component	HslUV protease complex
B	0016887	molecular_function	ATP hydrolysis activity
B	0036402	molecular_function	proteasome-activating activity
B	0043335	biological_process	protein unfolding
B	0051603	biological_process	proteolysis involved in protein catabolic process
B	1901800	biological_process	positive regulation of proteasomal protein catabolic process
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0008233	molecular_function	peptidase activity
C	0009376	cellular_component	HslUV protease complex
C	0016887	molecular_function	ATP hydrolysis activity
C	0036402	molecular_function	proteasome-activating activity
C	0043335	biological_process	protein unfolding
C	0051603	biological_process	proteolysis involved in protein catabolic process
C	1901800	biological_process	positive regulation of proteasomal protein catabolic process
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0008233	molecular_function	peptidase activity
D	0009376	cellular_component	HslUV protease complex
D	0016887	molecular_function	ATP hydrolysis activity
D	0036402	molecular_function	proteasome-activating activity
D	0043335	biological_process	protein unfolding
D	0051603	biological_process	proteolysis involved in protein catabolic process
D	1901800	biological_process	positive regulation of proteasomal protein catabolic process
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0008233	molecular_function	peptidase activity
E	0009376	cellular_component	HslUV protease complex
E	0016887	molecular_function	ATP hydrolysis activity
E	0036402	molecular_function	proteasome-activating activity
E	0043335	biological_process	protein unfolding
E	0051603	biological_process	proteolysis involved in protein catabolic process
E	1901800	biological_process	positive regulation of proteasomal protein catabolic process
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0008233	molecular_function	peptidase activity
F	0009376	cellular_component	HslUV protease complex
F	0016887	molecular_function	ATP hydrolysis activity
F	0036402	molecular_function	proteasome-activating activity
F	0043335	biological_process	protein unfolding
F	0051603	biological_process	proteolysis involved in protein catabolic process
F	1901800	biological_process	positive regulation of proteasomal protein catabolic process
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0008233	molecular_function	peptidase activity
G	0009376	cellular_component	HslUV protease complex
G	0016887	molecular_function	ATP hydrolysis activity
G	0036402	molecular_function	proteasome-activating activity
G	0043335	biological_process	protein unfolding
G	0051603	biological_process	proteolysis involved in protein catabolic process
G	1901800	biological_process	positive regulation of proteasomal protein catabolic process
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0008233	molecular_function	peptidase activity
H	0009376	cellular_component	HslUV protease complex
H	0016887	molecular_function	ATP hydrolysis activity
H	0036402	molecular_function	proteasome-activating activity
H	0043335	biological_process	protein unfolding
H	0051603	biological_process	proteolysis involved in protein catabolic process
H	1901800	biological_process	positive regulation of proteasomal protein catabolic process
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0008233	molecular_function	peptidase activity
I	0009376	cellular_component	HslUV protease complex
I	0016887	molecular_function	ATP hydrolysis activity
I	0036402	molecular_function	proteasome-activating activity
I	0043335	biological_process	protein unfolding
I	0051603	biological_process	proteolysis involved in protein catabolic process
I	1901800	biological_process	positive regulation of proteasomal protein catabolic process
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0008233	molecular_function	peptidase activity
J	0009376	cellular_component	HslUV protease complex
J	0016887	molecular_function	ATP hydrolysis activity
J	0036402	molecular_function	proteasome-activating activity
J	0043335	biological_process	protein unfolding
J	0051603	biological_process	proteolysis involved in protein catabolic process
J	1901800	biological_process	positive regulation of proteasomal protein catabolic process
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0008233	molecular_function	peptidase activity
K	0009376	cellular_component	HslUV protease complex
K	0016887	molecular_function	ATP hydrolysis activity
K	0036402	molecular_function	proteasome-activating activity
K	0043335	biological_process	protein unfolding
K	0051603	biological_process	proteolysis involved in protein catabolic process
K	1901800	biological_process	positive regulation of proteasomal protein catabolic process
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0008233	molecular_function	peptidase activity
L	0009376	cellular_component	HslUV protease complex
L	0016887	molecular_function	ATP hydrolysis activity
L	0036402	molecular_function	proteasome-activating activity
L	0043335	biological_process	protein unfolding
L	0051603	biological_process	proteolysis involved in protein catabolic process
L	1901800	biological_process	positive regulation of proteasomal protein catabolic process
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0008233	molecular_function	peptidase activity
M	0009376	cellular_component	HslUV protease complex
M	0016887	molecular_function	ATP hydrolysis activity
M	0036402	molecular_function	proteasome-activating activity
M	0043335	biological_process	protein unfolding
M	0051603	biological_process	proteolysis involved in protein catabolic process
M	1901800	biological_process	positive regulation of proteasomal protein catabolic process
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0008233	molecular_function	peptidase activity
N	0009376	cellular_component	HslUV protease complex
N	0016887	molecular_function	ATP hydrolysis activity
N	0036402	molecular_function	proteasome-activating activity
N	0043335	biological_process	protein unfolding
N	0051603	biological_process	proteolysis involved in protein catabolic process
N	1901800	biological_process	positive regulation of proteasomal protein catabolic process
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0008233	molecular_function	peptidase activity
O	0009376	cellular_component	HslUV protease complex
O	0016887	molecular_function	ATP hydrolysis activity
O	0036402	molecular_function	proteasome-activating activity
O	0043335	biological_process	protein unfolding
O	0051603	biological_process	proteolysis involved in protein catabolic process
O	1901800	biological_process	positive regulation of proteasomal protein catabolic process
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0008233	molecular_function	peptidase activity
P	0009376	cellular_component	HslUV protease complex
P	0016887	molecular_function	ATP hydrolysis activity
P	0036402	molecular_function	proteasome-activating activity
P	0043335	biological_process	protein unfolding
P	0051603	biological_process	proteolysis involved in protein catabolic process
P	1901800	biological_process	positive regulation of proteasomal protein catabolic process
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0008233	molecular_function	peptidase activity
Q	0009376	cellular_component	HslUV protease complex
Q	0016887	molecular_function	ATP hydrolysis activity
Q	0036402	molecular_function	proteasome-activating activity
Q	0043335	biological_process	protein unfolding
Q	0051603	biological_process	proteolysis involved in protein catabolic process
Q	1901800	biological_process	positive regulation of proteasomal protein catabolic process
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0008233	molecular_function	peptidase activity
R	0009376	cellular_component	HslUV protease complex
R	0016887	molecular_function	ATP hydrolysis activity
R	0036402	molecular_function	proteasome-activating activity
R	0043335	biological_process	protein unfolding
R	0051603	biological_process	proteolysis involved in protein catabolic process
R	1901800	biological_process	positive regulation of proteasomal protein catabolic process
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0008233	molecular_function	peptidase activity
S	0009376	cellular_component	HslUV protease complex
S	0016887	molecular_function	ATP hydrolysis activity
S	0036402	molecular_function	proteasome-activating activity
S	0043335	biological_process	protein unfolding
S	0051603	biological_process	proteolysis involved in protein catabolic process
S	1901800	biological_process	positive regulation of proteasomal protein catabolic process
T	0005524	molecular_function	ATP binding
T	0005737	cellular_component	cytoplasm
T	0008233	molecular_function	peptidase activity
T	0009376	cellular_component	HslUV protease complex
T	0016887	molecular_function	ATP hydrolysis activity
T	0036402	molecular_function	proteasome-activating activity
T	0043335	biological_process	protein unfolding
T	0051603	biological_process	proteolysis involved in protein catabolic process
T	1901800	biological_process	positive regulation of proteasomal protein catabolic process
U	0005524	molecular_function	ATP binding
U	0005737	cellular_component	cytoplasm
U	0008233	molecular_function	peptidase activity
U	0009376	cellular_component	HslUV protease complex
U	0016887	molecular_function	ATP hydrolysis activity
U	0036402	molecular_function	proteasome-activating activity
U	0043335	biological_process	protein unfolding
U	0051603	biological_process	proteolysis involved in protein catabolic process
U	1901800	biological_process	positive regulation of proteasomal protein catabolic process
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0008233	molecular_function	peptidase activity
V	0009376	cellular_component	HslUV protease complex
V	0016887	molecular_function	ATP hydrolysis activity
V	0036402	molecular_function	proteasome-activating activity
V	0043335	biological_process	protein unfolding
V	0051603	biological_process	proteolysis involved in protein catabolic process
V	1901800	biological_process	positive regulation of proteasomal protein catabolic process
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0008233	molecular_function	peptidase activity
W	0009376	cellular_component	HslUV protease complex
W	0016887	molecular_function	ATP hydrolysis activity
W	0036402	molecular_function	proteasome-activating activity
W	0043335	biological_process	protein unfolding
W	0051603	biological_process	proteolysis involved in protein catabolic process
W	1901800	biological_process	positive regulation of proteasomal protein catabolic process
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0008233	molecular_function	peptidase activity
X	0009376	cellular_component	HslUV protease complex
X	0016887	molecular_function	ATP hydrolysis activity
X	0036402	molecular_function	proteasome-activating activity
X	0043335	biological_process	protein unfolding
X	0051603	biological_process	proteolysis involved in protein catabolic process
X	1901800	biological_process	positive regulation of proteasomal protein catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00249

Chain	Residue	Details
M	VAL22
N	ARG417
H	ARG417
I	VAL22
I	GLY64
I	ASP280
I	GLU345
I	ARG417
J	VAL22
J	GLY64
J	ASP280
J	GLU345
O	VAL22
J	ARG417
K	VAL22
K	GLY64
K	ASP280
K	GLU345
K	ARG417
L	VAL22
L	GLY64
L	ASP280
L	GLU345
O	GLY64
L	ARG417
O	ASP280
O	GLU345
O	ARG417
P	VAL22
P	GLY64
P	ASP280
P	GLU345
M	GLY64
P	ARG417
Q	VAL22
Q	GLY64
Q	ASP280
Q	GLU345
Q	ARG417
R	VAL22
R	GLY64
R	ASP280
R	GLU345
M	ASP280
R	ARG417
S	VAL22
S	GLY64
S	ASP280
S	GLU345
S	ARG417
T	VAL22
T	GLY64
T	ASP280
T	GLU345
M	GLU345
T	ARG417
U	VAL22
U	GLY64
U	ASP280
U	GLU345
U	ARG417
V	VAL22
V	GLY64
V	ASP280
V	GLU345
M	ARG417
V	ARG417
W	VAL22
W	GLY64
W	ASP280
W	GLU345
W	ARG417
X	VAL22
X	GLY64
X	ASP280
X	GLU345
N	VAL22
X	ARG417
A	VAL22
A	GLY64
A	ASP280
A	GLU345
A	ARG417
B	VAL22
B	GLY64
B	ASP280
B	GLU345
N	GLY64
B	ARG417
C	VAL22
C	GLY64
C	ASP280
C	GLU345
C	ARG417
D	VAL22
D	GLY64
D	ASP280
D	GLU345
N	ASP280
D	ARG417
E	VAL22
E	GLY64
E	ASP280
E	GLU345
E	ARG417
F	VAL22
F	GLY64
F	ASP280
F	GLU345
N	GLU345
F	ARG417
G	VAL22
G	GLY64
G	ASP280
G	GLU345
G	ARG417
H	VAL22
H	GLY64
H	ASP280
H	GLU345

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)