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6KKE

THRb mutation with a novel agonist

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues15
Detailsbinding site for residue 8HO A 501
ChainResidue
APHE269
AASN331
AGLY344
ALEU346
AHOH609
AHOH620
AHOH629
AILE275
AALA279
AARG282
AMET313
ASER314
AARG316
AALA317
ALEU330

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:15466465, ECO:0007744|PDB:1Y0X
ChainResidueDetails
ALEU435
AARG282
AASN331

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PDB entries from 2024-06-12

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