6JZ6

b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0004565	molecular_function	beta-galactosidase activity
A	0004566	molecular_function	beta-glucuronidase activity
A	0005102	molecular_function	signaling receptor binding
A	0005615	cellular_component	extracellular space
A	0005975	biological_process	carbohydrate metabolic process
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0019391	biological_process	glucuronoside catabolic process
A	0030246	molecular_function	carbohydrate binding
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0004565	molecular_function	beta-galactosidase activity
B	0004566	molecular_function	beta-glucuronidase activity
B	0005102	molecular_function	signaling receptor binding
B	0005615	cellular_component	extracellular space
B	0005975	biological_process	carbohydrate metabolic process
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0019391	biological_process	glucuronoside catabolic process
B	0030246	molecular_function	carbohydrate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue CKX A 701

Chain	Residue
A	ASP167
A	LYS576
A	HOH902
A	HOH953
A	HOH1074
A	HIS335
A	GLU418
A	TYR474
A	TYR478
A	GLU512
A	TRP557
A	ARG570
A	ASN574

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site_id	AC2
Number of Residues	14
Details	binding site for residue CKX B 701

Chain	Residue
B	ASP167
B	HIS335
B	ASN417
B	GLU418
B	TYR474
B	TYR478
B	GLU512
B	TRP557
B	ARG570
B	ASN574
B	LYS576
B	HOH929
B	HOH930
B	HOH1049

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Functional Information from PROSITE/UniProt

site_id	PS00719
Number of Residues	26
Details	GLYCOSYL_HYDROL_F2_1 Glycosyl hydrolases family 2 signature 1. NcFRTSHYPyaeeWYqfaDeeGFLII

Chain	Residue	Details
A	ASN329-ILE354

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