6JXR

Structure of human T cell receptor-CD3 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0004888	molecular_function	transmembrane signaling receptor activity
a	0007166	biological_process	cell surface receptor signaling pathway
a	0016020	cellular_component	membrane
b	0004888	molecular_function	transmembrane signaling receptor activity
b	0007166	biological_process	cell surface receptor signaling pathway
b	0016020	cellular_component	membrane
d	0004888	molecular_function	transmembrane signaling receptor activity
d	0007166	biological_process	cell surface receptor signaling pathway
d	0016020	cellular_component	membrane
e	0004888	molecular_function	transmembrane signaling receptor activity
e	0007166	biological_process	cell surface receptor signaling pathway
e	0016020	cellular_component	membrane
f	0004888	molecular_function	transmembrane signaling receptor activity
f	0007166	biological_process	cell surface receptor signaling pathway
f	0016020	cellular_component	membrane
g	0004888	molecular_function	transmembrane signaling receptor activity
g	0007166	biological_process	cell surface receptor signaling pathway
g	0016020	cellular_component	membrane
m	0002250	biological_process	adaptive immune response
m	0005886	cellular_component	plasma membrane
m	0009617	biological_process	response to bacterium
m	0042101	cellular_component	T cell receptor complex
m	0042105	cellular_component	alpha-beta T cell receptor complex
m	0042605	molecular_function	peptide antigen binding
m	0046631	biological_process	alpha-beta T cell activation
m	0050852	biological_process	T cell receptor signaling pathway
n	0002250	biological_process	adaptive immune response
n	0005886	cellular_component	plasma membrane
n	0007166	biological_process	cell surface receptor signaling pathway
n	0042101	cellular_component	T cell receptor complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
n	ASN84
e	ASP23-ASP126

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site_id	SWS_FT_FI2
Number of Residues	22
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
n	THR279-LEU301
e	VAL127-SER152

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site_id	SWS_FT_FI3
Number of Residues	10
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
n	MET302-GLY312
e	LYS153-ILE207

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
n	ASN203
m	ASN199

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
m	ASN210
m	ASN246
b	TYR64
b	TYR72

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:8636209

Chain	Residue	Details
g	ASN52
g	ASN92

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site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:12522270, ECO:0007744|PubMed:15144186, ECO:0007744|PubMed:15592455, ECO:0007744|PubMed:19690332

Chain	Residue	Details
a	TYR111
a	TYR142
b	TYR111
b	TYR142

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
a	TYR123
a	TYR153
b	TYR123
b	TYR153

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