6JIZ

Apo structure of an imine reductase at 1.76 Angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003858	molecular_function	3-hydroxybutyrate dehydrogenase activity
A	0005829	cellular_component	cytosol
A	0016054	biological_process	organic acid catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0035064	molecular_function	methylated histone binding
A	0050661	molecular_function	NADP binding
B	0000166	molecular_function	nucleotide binding
B	0003858	molecular_function	3-hydroxybutyrate dehydrogenase activity
B	0005829	cellular_component	cytosol
B	0016054	biological_process	organic acid catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0035064	molecular_function	methylated histone binding
B	0050661	molecular_function	NADP binding
C	0000166	molecular_function	nucleotide binding
C	0003858	molecular_function	3-hydroxybutyrate dehydrogenase activity
C	0005829	cellular_component	cytosol
C	0016054	biological_process	organic acid catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0035064	molecular_function	methylated histone binding
C	0050661	molecular_function	NADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ACT A 301

Chain	Residue
A	GLN73
A	NH4305
A	HOH413
A	HOH486

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ACT A 302

Chain	Residue
A	GLN73
A	TYR76
A	HOH446
A	HOH627

---

site_id	AC3
Number of Residues	3
Details	binding site for residue ACT A 303

Chain	Residue
A	HOH450
B	HOH435
A	ARG158

---

site_id	AC4
Number of Residues	1
Details	binding site for residue CL A 304

Chain	Residue
A	TRP287

---

site_id	AC5
Number of Residues	4
Details	binding site for residue NH4 A 305

Chain	Residue
A	ACT301
A	HOH417
A	HOH520
A	HOH533

---

site_id	AC6
Number of Residues	3
Details	binding site for residue NA A 306

Chain	Residue
A	THR70
A	HOH641
A	HOH659

---

site_id	AC7
Number of Residues	6
Details	binding site for residue ACT B 301

Chain	Residue
B	LEU231
B	GLY234
B	TYR291
B	GLU292
B	LYS295
C	GLU199

---

site_id	AC8
Number of Residues	2
Details	binding site for residue ACT B 302

Chain	Residue
B	HOH445
B	HOH489

---

site_id	AC9
Number of Residues	3
Details	binding site for residue ACT B 303

Chain	Residue
A	LYS111
B	ASN235
B	HOH524

---

site_id	AD1
Number of Residues	1
Details	binding site for residue CL B 304

Chain	Residue
B	ARG103

---

site_id	AD2
Number of Residues	1
Details	binding site for residue CL B 305

Chain	Residue
B	ARG229

---

site_id	AD3
Number of Residues	6
Details	binding site for residue LW9 B 306

Chain	Residue
B	LEU225
B	ALA241
B	MET245
B	MET246
B	HOH421
C	NAP302

---

site_id	AD4
Number of Residues	4
Details	binding site for residue NA C 301

Chain	Residue
B	LYS296
B	LYS297
B	HOH598
C	GLY261

---

site_id	AD5
Number of Residues	38
Details	binding site for residue NAP C 302

Chain	Residue
B	LEU240
B	MET245
B	THR249
B	LW9306
B	HOH421
C	GLY12
C	LEU13
C	GLY14
C	PRO15
C	MET16
C	ASN35
C	ARG36
C	THR37
C	ARG40
C	SER68
C	LEU69
C	THR70
C	ALA74
C	ASP77
C	ILE78
C	SER95
C	SER96
C	VAL121
C	THR123
C	PRO124
C	ALA125
C	TYR171
C	HOH424
C	HOH429
C	HOH441
C	HOH475
C	HOH494
C	HOH495
C	HOH502
C	HOH523
C	HOH534
C	HOH547
C	HOH559

---

site_id	AD6
Number of Residues	4
Details	binding site for residue ACT C 303

Chain	Residue
C	GLN73
C	HOH417
C	HOH444
C	HOH488

---

site_id	AD7
Number of Residues	4
Details	binding site for residue CL C 304

Chain	Residue
B	GLY261
C	LYS296
C	LYS297
C	HOH652

---

site_id	AD8
Number of Residues	5
Details	binding site for residue CL C 305

Chain	Residue
C	GLU83
C	TRP108
C	LYS111
C	HIS112
C	HOH655

---

site_id	AD9
Number of Residues	3
Details	binding site for residue EDO C 306

Chain	Residue
C	GLN18
C	ARG40
C	HOH528

---

site_id	AE1
Number of Residues	2
Details	binding site for residue EDO C 307

Chain	Residue
C	GLN73
C	TYR76

---