6JAK

OtsA apo structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0003825	molecular_function	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
A	0005992	biological_process	trehalose biosynthetic process
A	0006950	biological_process	response to stress
A	0006970	biological_process	response to osmotic stress
A	0006974	biological_process	DNA damage response
A	0016757	molecular_function	glycosyltransferase activity
A	0016758	molecular_function	hexosyltransferase activity
A	0070415	biological_process	trehalose metabolism in response to cold stress
B	0003824	molecular_function	catalytic activity
B	0003825	molecular_function	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
B	0005992	biological_process	trehalose biosynthetic process
B	0006950	biological_process	response to stress
B	0006970	biological_process	response to osmotic stress
B	0006974	biological_process	DNA damage response
B	0016757	molecular_function	glycosyltransferase activity
B	0016758	molecular_function	hexosyltransferase activity
B	0070415	biological_process	trehalose metabolism in response to cold stress
C	0003824	molecular_function	catalytic activity
C	0003825	molecular_function	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
C	0005992	biological_process	trehalose biosynthetic process
C	0006950	biological_process	response to stress
C	0006970	biological_process	response to osmotic stress
C	0006974	biological_process	DNA damage response
C	0016757	molecular_function	glycosyltransferase activity
C	0016758	molecular_function	hexosyltransferase activity
C	0070415	biological_process	trehalose metabolism in response to cold stress
D	0003824	molecular_function	catalytic activity
D	0003825	molecular_function	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
D	0005992	biological_process	trehalose biosynthetic process
D	0006950	biological_process	response to stress
D	0006970	biological_process	response to osmotic stress
D	0006974	biological_process	DNA damage response
D	0016757	molecular_function	glycosyltransferase activity
D	0016758	molecular_function	hexosyltransferase activity
D	0070415	biological_process	trehalose metabolism in response to cold stress

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:12498887, ECO:0000269|PubMed:20077550, ECO:0007744|PDB:1GZ5, ECO:0007744|PDB:2WTX

Chain	Residue	Details
A	ARG10
A	TYR77
A	ASP131
A	ARG301
B	ARG10
B	TYR77
B	ASP131
B	ARG301
C	ARG10
C	TYR77
C	ASP131
C	ARG301
D	ARG10
D	TYR77
D	ASP131
D	ARG301

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000305|PubMed:12498887, ECO:0000305|PubMed:14570926, ECO:0000305|PubMed:20077550, ECO:0007744|PDB:1GZ5, ECO:0007744|PDB:2WTX

Chain	Residue	Details
A	GLY22
B	GLY22
C	GLY22
D	GLY22

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site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000305|PubMed:12498887, ECO:0000305|PubMed:14570926, ECO:0000305|PubMed:20077550, ECO:0007744|PDB:1GZ5, ECO:0007744|PDB:1UQT, ECO:0007744|PDB:1UQU, ECO:0007744|PDB:2WTX

Chain	Residue	Details
B	ARG263
B	LYS268
B	PHE340
B	LEU366
C	ARG263
C	LYS268
C	PHE340
C	LEU366
D	ARG263
D	LYS268
D	PHE340
D	LEU366
A	ARG263
A	LYS268
A	PHE340
A	LEU366

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site_id	SWS_FT_FI4
Number of Residues	8
Details	SITE: Involved in alpha anomer selectivity => ECO:0000305|PubMed:12498887

Chain	Residue	Details
A	TRP86
A	ILE156
B	TRP86
B	ILE156
C	TRP86
C	ILE156
D	TRP86
D	ILE156

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	2
Details	M-CSA 622

Chain	Residue	Details
A	HIS155	electrostatic stabiliser
A	ASP362	electrostatic stabiliser

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site_id	MCSA2
Number of Residues	2
Details	M-CSA 622

Chain	Residue	Details
B	HIS155	electrostatic stabiliser
B	ASP362	electrostatic stabiliser

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site_id	MCSA3
Number of Residues	2
Details	M-CSA 622

Chain	Residue	Details
C	HIS155	electrostatic stabiliser
C	ASP362	electrostatic stabiliser

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site_id	MCSA4
Number of Residues	2
Details	M-CSA 622

Chain	Residue	Details
D	HIS155	electrostatic stabiliser
D	ASP362	electrostatic stabiliser

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