Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| A | 0046677 | biological_process | response to antibiotic |
| B | 0008800 | molecular_function | beta-lactamase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017001 | biological_process | antibiotic catabolic process |
| B | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| B | 0046677 | biological_process | response to antibiotic |
| C | 0008800 | molecular_function | beta-lactamase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0017001 | biological_process | antibiotic catabolic process |
| C | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| C | 0046677 | biological_process | response to antibiotic |
| D | 0008800 | molecular_function | beta-lactamase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0017001 | biological_process | antibiotic catabolic process |
| D | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| D | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue BHU A 301 |
| Chain | Residue |
| A | CYS69 |
| A | SER70 |
| A | ASN132 |
| A | GLU166 |
| A | ASN170 |
| A | THR237 |
| A | CYS238 |
| A | ACY309 |
| A | HOH482 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 302 |
| Chain | Residue |
| A | TYR97 |
| A | PEG303 |
| A | HOH404 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 303 |
| Chain | Residue |
| A | ARG96 |
| A | PEG302 |
| A | HOH415 |
| A | HOH514 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 304 |
| Chain | Residue |
| A | ALA101 |
| A | HOH415 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 305 |
| Chain | Residue |
| A | ILE108 |
| A | LYS111 |
| A | TYR129 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 306 |
| Chain | Residue |
| A | LYS212 |
| A | ALA230 |
| A | TRP251 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 307 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 308 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue ACY A 309 |
| Chain | Residue |
| A | SER70 |
| A | SER130 |
| A | LYS234 |
| A | THR235 |
| A | GLY236 |
| A | THR237 |
| A | BHU301 |
| A | HOH485 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ACY A 310 |
| Chain | Residue |
| A | SER275 |
| A | GLU276 |
| A | ALA277 |
| A | HOH492 |
| site_id | AD2 |
| Number of Residues | 8 |
| Details | binding site for residue BHU B 301 |
| Chain | Residue |
| B | CYS69 |
| B | SER70 |
| B | TRP105 |
| B | ASN132 |
| B | GLU166 |
| B | ASN170 |
| B | THR237 |
| B | ACY306 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 302 |
| Chain | Residue |
| B | ILE108 |
| B | LYS111 |
| B | LEU287 |
| B | PEG303 |
| B | HOH401 |
| B | HOH459 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue PEG B 303 |
| Chain | Residue |
| B | THR215 |
| B | ASN218 |
| B | ALA224 |
| B | VAL225 |
| B | PRO226 |
| B | PEG302 |
| B | HOH401 |
| B | HOH402 |
| B | HOH404 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 304 |
| Chain | Residue |
| B | GLN85 |
| B | GLN86 |
| B | ALA88 |
| D | GLN85 |
| D | PEG306 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 305 |
| Chain | Residue |
| B | GLN85 |
| B | HOH428 |
| D | SER84 |
| D | GLN85 |
| D | ALA88 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue ACY B 306 |
| Chain | Residue |
| B | SER70 |
| B | SER130 |
| B | LYS234 |
| B | THR235 |
| B | GLY236 |
| B | THR237 |
| B | BHU301 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue ACY B 307 |
| Chain | Residue |
| B | SER275 |
| B | GLU276 |
| B | ALA277 |
| B | HOH458 |
| B | HOH465 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue BHU C 301 |
| Chain | Residue |
| C | CYS69 |
| C | SER70 |
| C | ASN132 |
| C | GLU166 |
| C | ASN170 |
| C | THR237 |
| C | CYS238 |
| C | ACY305 |
| C | HOH463 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 302 |
| Chain | Residue |
| C | ASN100 |
| C | PEG303 |
| C | HOH510 |
| D | GLY54 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue PEG C 303 |
| Chain | Residue |
| C | ASN100 |
| C | PEG302 |
| C | HOH491 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 304 |
| Chain | Residue |
| C | SER275 |
| C | GLU276 |
| C | ALA277 |
| C | HOH426 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue ACY C 305 |
| Chain | Residue |
| C | SER70 |
| C | SER130 |
| C | LYS234 |
| C | THR235 |
| C | GLY236 |
| C | THR237 |
| C | BHU301 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue BHU D 301 |
| Chain | Residue |
| D | CYS69 |
| D | SER70 |
| D | ASN132 |
| D | GLU166 |
| D | ASN170 |
| D | THR237 |
| D | ACY305 |
| D | HOH481 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue PEG D 302 |
| Chain | Residue |
| D | LYS212 |
| D | ALA230 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue PEG D 303 |
| Chain | Residue |
| D | LEU167 |
| D | ASN170 |
| D | CYS238 |
| D | VAL240 |
| D | HOH545 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 304 |
| Chain | Residue |
| D | SER275 |
| D | GLU276 |
| D | ALA277 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue ACY D 305 |
| Chain | Residue |
| D | SER70 |
| D | SER130 |
| D | LYS234 |
| D | THR235 |
| D | GLY236 |
| D | THR237 |
| D | BHU301 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG D 306 |
| Chain | Residue |
| B | PEG304 |
| D | GLN85 |
| D | HOH427 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Acyl-ester intermediate => ECO:0000250 |
| Chain | Residue | Details |
| A | SER70 | |
| B | SER70 | |
| C | SER70 | |
| D | SER70 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU168 | |
| B | GLU168 | |
| C | GLU168 | |
| D | GLU168 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS234 | |
| B | LYS234 | |
| C | LYS234 | |
| D | LYS234 | |
