Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008395 | molecular_function | steroid hydroxylase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 20 |
Details | binding site for residue HEM A 401 |
Chain | Residue |
A | ILE84 |
A | LEU281 |
A | THR286 |
A | ARG289 |
A | GLY339 |
A | GLY341 |
A | ILE344 |
A | HIS345 |
A | CYS347 |
A | GLY349 |
A | HOH542 |
A | LEU85 |
A | HOH607 |
A | HIS92 |
A | ARG96 |
A | PHE103 |
A | ALA235 |
A | THR239 |
A | GLN243 |
A | MET276 |
site_id | AC2 |
Number of Residues | 11 |
Details | binding site for residue B9U A 402 |
Chain | Residue |
A | THR82 |
A | LEU85 |
A | PHE169 |
A | VAL231 |
A | ALA235 |
A | THR286 |
A | PHE287 |
A | GLN387 |
A | VAL388 |
A | HOH542 |
A | HOH576 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGyGIHRCLG |
Chain | Residue | Details |
A | PHE340-GLY349 | |