6HNV

Crystal structure of aminotransferase Aro9 from C. Albicans with ligands

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000949	biological_process	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway
A	0005575	cellular_component	cellular_component
A	0006571	biological_process	tyrosine biosynthetic process
A	0008483	molecular_function	transaminase activity
A	0008643	biological_process	carbohydrate transport
A	0008793	molecular_function	aromatic-amino-acid:2-oxoglutarate aminotransferase activity
A	0009058	biological_process	biosynthetic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009074	biological_process	aromatic amino acid family catabolic process
A	0009094	biological_process	L-phenylalanine biosynthetic process
A	0019477	biological_process	L-lysine catabolic process
A	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
A	0030170	molecular_function	pyridoxal phosphate binding
A	0036137	molecular_function	kynurenine aminotransferase activity
A	0045454	biological_process	cell redox homeostasis
A	0047536	molecular_function	2-aminoadipate transaminase activity
A	0097052	biological_process	L-kynurenine metabolic process
B	0000949	biological_process	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway
B	0005575	cellular_component	cellular_component
B	0006571	biological_process	tyrosine biosynthetic process
B	0008483	molecular_function	transaminase activity
B	0008643	biological_process	carbohydrate transport
B	0008793	molecular_function	aromatic-amino-acid:2-oxoglutarate aminotransferase activity
B	0009058	biological_process	biosynthetic process
B	0009072	biological_process	aromatic amino acid metabolic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009074	biological_process	aromatic amino acid family catabolic process
B	0009094	biological_process	L-phenylalanine biosynthetic process
B	0019477	biological_process	L-lysine catabolic process
B	0019878	biological_process	lysine biosynthetic process via aminoadipic acid
B	0030170	molecular_function	pyridoxal phosphate binding
B	0036137	molecular_function	kynurenine aminotransferase activity
B	0045454	biological_process	cell redox homeostasis
B	0047536	molecular_function	2-aminoadipate transaminase activity
B	0097052	biological_process	L-kynurenine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue PLP A 601

Chain	Residue
A	GLY165
A	THR338
A	SER340
A	LYS341
A	ARG348
B	TYR130
B	UN1602
B	OOG605
A	ALA166
A	SER167
A	PHE191
A	ILE247
A	ASN252
A	ASP280
A	PRO282
A	TYR283

---

site_id	AC2
Number of Residues	4
Details	binding site for residue BCN A 602

Chain	Residue
A	TYR423
A	ASP432
A	HOH730
A	HOH745

---

site_id	AC3
Number of Residues	4
Details	binding site for residue MPD A 603

Chain	Residue
A	HIS6
A	ASP274
B	GLU501
B	ARG508

---

site_id	AC4
Number of Residues	6
Details	binding site for residue PHE A 604

Chain	Residue
A	TYR130
A	ALA131
A	ARG371
A	PPY605
A	HOH701
A	HOH715

---

site_id	AC5
Number of Residues	7
Details	binding site for residue PPY A 605

Chain	Residue
A	TYR130
A	ARG371
A	PHE604
A	HOH701
B	SER167
B	ARG348
B	PLP601

---

site_id	AC6
Number of Residues	6
Details	binding site for residue UN1 B 602

Chain	Residue
A	SER167
A	ARG348
A	PLP601
B	TYR130
B	ARG371
B	OOG605

---

site_id	AC7
Number of Residues	6
Details	binding site for residue BCN B 603

Chain	Residue
A	PRO29
A	GLU311
A	GLU397
B	GLN453
B	LEU457
B	GLU522

---

site_id	AC8
Number of Residues	6
Details	binding site for residue BCN B 604

Chain	Residue
A	ASP213
B	PHE212
B	ASP213
B	ASN214
B	ASP429
B	LYS442

---

site_id	AC9
Number of Residues	6
Details	binding site for residue OOG B 605

Chain	Residue
A	PHE191
A	PLP601
B	TYR130
B	ALA131
B	ARG371
B	UN1602

---

site_id	AD1
Number of Residues	17
Details	binding site for Di-peptide PLP B 601 and LYS B 341

Chain	Residue
A	GLY44
A	TYR130
A	PPY605
B	GLY165
B	ALA166
B	SER167
B	PHE191
B	ASN252
B	ASP280
B	TYR283
B	THR338
B	PHE339
B	SER340
B	LEU342
B	ARG348
B	MET402
B	MET437

---