Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | EDO422 |
| A | EDO425 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 402 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | HOH550 |
| B | EDO405 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 404 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | P6G442 |
| B | EDO409 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | HOH516 |
| A | PEG437 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | PEG436 |
| A | P6G442 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | EDO422 |
| A | HOH616 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | EDO419 |
| A | P4G429 |
| A | HOH546 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | TYR107 |
| A | GLU117 |
| A | ARG120 |
| A | PEG435 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 411 |
| Chain | Residue |
| A | EDO404 |
| A | EDO416 |
| A | HOH561 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 412 |
| Chain | Residue |
| A | P6G442 |
| A | HOH655 |
| B | EDO413 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 413 |
| Chain | Residue |
| A | TYR253 |
| A | HOH595 |
| B | LYS111 |
| B | PEG424 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 415 |
| Chain | Residue |
| A | HOH569 |
| A | HOH587 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 416 |
| Chain | Residue |
| A | EDO411 |
| A | PEG438 |
| A | HOH534 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 417 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 418 |
| Chain | Residue |
| A | HOH633 |
| B | EDO406 |
| B | P4G418 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 419 |
| Chain | Residue |
| A | EDO409 |
| A | EDO420 |
| A | P4G429 |
| A | HOH558 |
| A | HOH592 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 420 |
| Chain | Residue |
| A | EDO419 |
| A | P4G429 |
| A | PEG439 |
| A | HOH592 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 421 |
| Chain | Residue |
| A | P4G430 |
| A | HOH574 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 422 |
| Chain | Residue |
| A | EDO401 |
| A | EDO408 |
| A | P4G430 |
| A | HOH616 |
| A | HOH647 |
| site_id | AE4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 424 |
| site_id | AE5 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 425 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 426 |
| Chain | Residue |
| A | P4G431 |
| A | HOH541 |
| A | HOH638 |
| A | HOH645 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue P4G A 429 |
| Chain | Residue |
| A | EDO409 |
| A | EDO419 |
| A | EDO420 |
| A | PEG439 |
| site_id | AE8 |
| Number of Residues | 3 |
| Details | binding site for residue P4G A 430 |
| Chain | Residue |
| A | EDO421 |
| A | EDO422 |
| A | EDO424 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue P4G A 431 |
| Chain | Residue |
| A | EDO402 |
| A | EDO426 |
| A | PEG436 |
| A | HOH644 |
| site_id | AF1 |
| Number of Residues | 18 |
| Details | binding site for residue G9Z A 432 |
| Chain | Residue |
| A | TYR37 |
| A | PHE41 |
| A | GLU89 |
| A | PHE130 |
| A | PRO162 |
| A | SER163 |
| A | ASP164 |
| A | THR166 |
| A | ALA208 |
| A | ARG229 |
| A | GLU252 |
| A | TYR288 |
| A | HOH525 |
| A | HOH543 |
| A | HOH544 |
| A | HOH545 |
| A | HOH599 |
| A | HOH608 |
| site_id | AF2 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 433 |
| site_id | AF3 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 434 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 435 |
| Chain | Residue |
| A | PRO52 |
| A | ALA56 |
| A | PHE272 |
| A | GLU277 |
| A | EDO410 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 436 |
| Chain | Residue |
| A | P4G431 |
| A | P6G442 |
| A | HOH555 |
| A | EDO407 |
| site_id | AF6 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 437 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 438 |
| Chain | Residue |
| A | EDO416 |
| A | HOH573 |
| B | EDO406 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 439 |
| Chain | Residue |
| A | EDO420 |
| A | P4G429 |
| A | HOH547 |
| B | PEG421 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 440 |
| Chain | Residue |
| A | ASN321 |
| A | LYS323 |
| A | HOH566 |
| B | ASN271 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue P6G A 442 |
| Chain | Residue |
| A | EDO405 |
| A | EDO407 |
| A | EDO412 |
| A | PEG436 |
| A | HOH509 |
| A | HOH563 |
| site_id | AG2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 401 |
| Chain | Residue |
| B | SER36 |
| B | TYR37 |
| B | THR65 |
| B | GLY66 |
| B | THR67 |
| B | HOH679 |
| site_id | AG3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | TYR69 |
| B | PRO91 |
| B | ALA92 |
| B | SER95 |
| B | ASP164 |
| B | TYR329 |
| B | HOH510 |
| B | HOH642 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| B | TYR107 |
| B | ARG120 |
| B | THR121 |
| B | LYS122 |
| B | HOH534 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | EDO405 |
| B | EDO408 |
| B | HOH647 |
| site_id | AG6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| A | EDO403 |
| B | EDO404 |
| B | HOH611 |
| site_id | AG7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| A | EDO418 |
| A | PEG438 |
| B | EDO408 |
| B | P4G418 |
| B | HOH627 |
| site_id | AG8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 407 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 408 |
| Chain | Residue |
| B | EDO404 |
| B | EDO406 |
| B | HOH566 |
| B | HOH649 |
| site_id | AH1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 409 |
| Chain | Residue |
| A | EDO405 |
| B | HOH617 |
| B | HOH658 |
| site_id | AH2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 411 |
| Chain | Residue |
| B | ASP187 |
| B | EDO416 |
| B | P4G417 |
| site_id | AH3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 412 |
| Chain | Residue |
| B | P4G418 |
| B | HOH636 |
| B | HOH639 |
| site_id | AH4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 413 |
| site_id | AH5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 414 |
| Chain | Residue |
| B | EDO407 |
| B | HOH560 |
| site_id | AH6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 415 |
| Chain | Residue |
| B | ASP210 |
| B | LEU214 |
| B | GLN217 |
| B | HOH635 |
| site_id | AH7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 416 |
| Chain | Residue |
| B | EDO411 |
| B | PEG423 |
| site_id | AH8 |
| Number of Residues | 3 |
| Details | binding site for residue P4G B 417 |
| Chain | Residue |
| B | EDO411 |
| B | PEG422 |
| B | HOH583 |
| site_id | AH9 |
| Number of Residues | 6 |
| Details | binding site for residue P4G B 418 |
| Chain | Residue |
| A | EDO418 |
| B | EDO406 |
| B | EDO412 |
| B | P4G419 |
| B | HOH556 |
| B | HOH576 |
| site_id | AI1 |
| Number of Residues | 2 |
| Details | binding site for residue P4G B 419 |
| Chain | Residue |
| B | P4G418 |
| B | PEG423 |
| site_id | AI2 |
| Number of Residues | 18 |
| Details | binding site for residue G9Z B 420 |
| Chain | Residue |
| B | TYR37 |
| B | PHE41 |
| B | GLU89 |
| B | MET128 |
| B | PHE130 |
| B | PRO162 |
| B | SER163 |
| B | THR166 |
| B | ALA208 |
| B | ARG229 |
| B | GLU252 |
| B | TYR288 |
| B | HOH504 |
| B | HOH506 |
| B | HOH512 |
| B | HOH588 |
| B | HOH606 |
| B | HOH651 |
| site_id | AI3 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 421 |
| Chain | Residue |
| A | PEG439 |
| B | HOH532 |
| site_id | AI4 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 422 |
| Chain | Residue |
| B | P4G417 |
| B | HOH626 |
| site_id | AI5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 423 |
| Chain | Residue |
| B | EDO416 |
| B | P4G419 |
| B | HOH521 |
| site_id | AI6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 424 |
| Chain | Residue |
| A | SER322 |
| A | ASN326 |
| A | EDO413 |
| B | LYS111 |
