Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6HIY

Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the body of the small mitoribosomal subunit in complex with mt-IF-3

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
CE	0003735	molecular_function	structural constituent of ribosome
CE	0005737	cellular_component	cytoplasm
CE	0005739	cellular_component	mitochondrion
CE	0005763	cellular_component	mitochondrial small ribosomal subunit
CE	0005840	cellular_component	ribosome
CE	0006412	biological_process	translation
CF	0005739	cellular_component	mitochondrion
CF	0005763	cellular_component	mitochondrial small ribosomal subunit
CH	0000314	cellular_component	organellar small ribosomal subunit
CH	0003735	molecular_function	structural constituent of ribosome
CH	0005737	cellular_component	cytoplasm
CH	0005739	cellular_component	mitochondrion
CH	0005763	cellular_component	mitochondrial small ribosomal subunit
CH	0005840	cellular_component	ribosome
CH	0006412	biological_process	translation
CH	0020023	cellular_component	kinetoplast
CH	0043229	cellular_component	intracellular organelle
CH	1990904	cellular_component	ribonucleoprotein complex
CI	0003735	molecular_function	structural constituent of ribosome
CI	0005739	cellular_component	mitochondrion
CI	0005763	cellular_component	mitochondrial small ribosomal subunit
CI	0005840	cellular_component	ribosome
CI	0006412	biological_process	translation
CI	1990904	cellular_component	ribonucleoprotein complex
CK	0003735	molecular_function	structural constituent of ribosome
CK	0005739	cellular_component	mitochondrion
CK	0005763	cellular_component	mitochondrial small ribosomal subunit
CK	0005840	cellular_component	ribosome
CK	0006412	biological_process	translation
CK	1990904	cellular_component	ribonucleoprotein complex
CO	0005739	cellular_component	mitochondrion
CO	0005763	cellular_component	mitochondrial small ribosomal subunit
CP	0005737	cellular_component	cytoplasm
CP	0005739	cellular_component	mitochondrion
CP	0005763	cellular_component	mitochondrial small ribosomal subunit
CQ	0000314	cellular_component	organellar small ribosomal subunit
CQ	0003735	molecular_function	structural constituent of ribosome
CQ	0005737	cellular_component	cytoplasm
CQ	0005739	cellular_component	mitochondrion
CQ	0005763	cellular_component	mitochondrial small ribosomal subunit
CQ	0005840	cellular_component	ribosome
CQ	0006412	biological_process	translation
CQ	1990904	cellular_component	ribonucleoprotein complex
CR	0003723	molecular_function	RNA binding
CR	0005737	cellular_component	cytoplasm
CR	0005739	cellular_component	mitochondrion
CR	0005763	cellular_component	mitochondrial small ribosomal subunit
CR	0043631	biological_process	obsolete RNA polyadenylation
CR	0048255	biological_process	mRNA stabilization
CU	0005739	cellular_component	mitochondrion
CZ	0005739	cellular_component	mitochondrion
Ca	0005739	cellular_component	mitochondrion
Ca	0005763	cellular_component	mitochondrial small ribosomal subunit
Cb	0005737	cellular_component	cytoplasm
Cb	0005739	cellular_component	mitochondrion
Cb	0005763	cellular_component	mitochondrial small ribosomal subunit
Cb	0097014	cellular_component	ciliary plasm
Cd	0005739	cellular_component	mitochondrion
Cd	0005763	cellular_component	mitochondrial small ribosomal subunit
Cj	0005739	cellular_component	mitochondrion
Cj	0005763	cellular_component	mitochondrial small ribosomal subunit
Cm	0005737	cellular_component	cytoplasm
Cn	0005739	cellular_component	mitochondrion
Cn	0020023	cellular_component	kinetoplast
Cp	0005739	cellular_component	mitochondrion
Cp	0005763	cellular_component	mitochondrial small ribosomal subunit
Cq	0004784	molecular_function	superoxide dismutase activity
Cq	0005739	cellular_component	mitochondrion
Cq	0006801	biological_process	superoxide metabolic process
Cq	0016491	molecular_function	oxidoreductase activity
Cq	0019430	biological_process	removal of superoxide radicals
Cq	0046872	molecular_function	metal ion binding
Cr	0004784	molecular_function	superoxide dismutase activity
Cr	0005739	cellular_component	mitochondrion
Cr	0005763	cellular_component	mitochondrial small ribosomal subunit
Cr	0006801	biological_process	superoxide metabolic process
Cr	0019430	biological_process	removal of superoxide radicals
Cr	0046872	molecular_function	metal ion binding
Cv	0003860	molecular_function	3-hydroxyisobutyryl-CoA hydrolase activity
Cv	0004300	molecular_function	enoyl-CoA hydratase activity
Cv	0005737	cellular_component	cytoplasm
Cv	0005739	cellular_component	mitochondrion
Cv	0005763	cellular_component	mitochondrial small ribosomal subunit
Cv	0006635	biological_process	fatty acid beta-oxidation
Cv	0016787	molecular_function	hydrolase activity
DA	0005739	cellular_component	mitochondrion
DA	0005763	cellular_component	mitochondrial small ribosomal subunit
DD	0000963	biological_process	mitochondrial RNA processing
DD	0005737	cellular_component	cytoplasm
DD	0005739	cellular_component	mitochondrion
DD	0031019	cellular_component	mitochondrial mRNA editing complex
DI	0005739	cellular_component	mitochondrion
DI	0005763	cellular_component	mitochondrial small ribosomal subunit
DL	0005739	cellular_component	mitochondrion
DL	0005763	cellular_component	mitochondrial small ribosomal subunit
DM	0005739	cellular_component	mitochondrion
DM	0005763	cellular_component	mitochondrial small ribosomal subunit
DN	0005739	cellular_component	mitochondrion
DN	0005763	cellular_component	mitochondrial small ribosomal subunit
DO	0005739	cellular_component	mitochondrion
DO	0005763	cellular_component	mitochondrial small ribosomal subunit
DO	0009372	biological_process	quorum sensing
DO	0044145	biological_process	modulation of formation of structure involved in a symbiotic process
DP	0005737	cellular_component	cytoplasm
DP	0005763	cellular_component	mitochondrial small ribosomal subunit
DQ	0005737	cellular_component	cytoplasm
DQ	0005739	cellular_component	mitochondrion
DQ	0005829	cellular_component	cytosol
DQ	0010738	biological_process	regulation of protein kinase A signaling
DQ	0034237	molecular_function	protein kinase A regulatory subunit binding
DR	0005739	cellular_component	mitochondrion
DR	0005763	cellular_component	mitochondrial small ribosomal subunit
DS	0005739	cellular_component	mitochondrion
DS	0005763	cellular_component	mitochondrial small ribosomal subunit
DU	0005739	cellular_component	mitochondrion
DU	0005763	cellular_component	mitochondrial small ribosomal subunit
DZ	0005739	cellular_component	mitochondrion
DZ	0005763	cellular_component	mitochondrial small ribosomal subunit

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN DA 1801

Chain	Residue
DA	CYS291
DA	CYS294
DA	CYS304
DA	HIS323

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN DS 1001

Chain	Residue
DS	CYS98
DS	CYS101
DS	CYS119
DS	CYS122

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN DS 1002

Chain	Residue
DS	CYS178
DS	CYS211
DS	CYS214
DS	CYS175

site_id	AC4
Number of Residues	3
Details	binding site for residue MG CO 501

Chain	Residue
CA	A91
CO	ASP405
CO	ASN429

site_id	AC5
Number of Residues	2
Details	binding site for residue MG CQ 401

Chain	Residue
CQ	HIS39
Da	HIS12

site_id	AC6
Number of Residues	2
Details	binding site for residue MG Ca 701

Chain	Residue
Ca	ARG363
DD	GLY766

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN Cr 501

Chain	Residue
Cr	HIS55
Cr	CYS59
Cr	CYS82
Cr	CYS85

site_id	AC8
Number of Residues	1
Details	binding site for residue MG Cv 1301

Chain	Residue
Cv	ASP30

site_id	AC9
Number of Residues	1
Details	binding site for residue MG CA 701

Chain	Residue
CA	A27

site_id	AD1
Number of Residues	1
Details	binding site for residue MG CA 702

Chain	Residue
CA	U65

site_id	AD2
Number of Residues	3
Details	binding site for residue MG CA 703

Chain	Residue
CA	U65
CA	U66
CA	A133

site_id	AD3
Number of Residues	3
Details	binding site for residue MG CA 704

Chain	Residue
CA	A60
CA	A61
CA	A155

site_id	AD4
Number of Residues	3
Details	binding site for residue MG CA 705

Chain	Residue
CA	A68
CA	A93
CA	U94

site_id	AD5
Number of Residues	1
Details	binding site for residue MG CA 706

Chain	Residue
CA	U69

site_id	AD6
Number of Residues	3
Details	binding site for residue MG CA 707

Chain	Residue
CA	U142
CA	U143
CA	G147

site_id	AD7
Number of Residues	3
Details	binding site for residue MG CA 708

Chain	Residue
CA	U231
CA	G232
CA	U246

site_id	AD8
Number of Residues	1
Details	binding site for residue MG CA 709

Chain	Residue
CA	C237

site_id	AD9
Number of Residues	1
Details	binding site for residue MG CA 710

Chain	Residue
CA	U339

site_id	AE1
Number of Residues	2
Details	binding site for residue MG CA 711

Chain	Residue
CA	A571
CA	A572

site_id	AE2
Number of Residues	2
Details	binding site for residue MG CA 712

Chain	Residue
CA	U562
CA	U563

site_id	AE3
Number of Residues	2
Details	binding site for residue MG CA 715

Chain	Residue
CA	U592
CA	A593

site_id	AE4
Number of Residues	2
Details	binding site for residue MG CA 717

Chain	Residue
CA	U281
CA	A367

site_id	AE5
Number of Residues	2
Details	binding site for residue MG CA 718

Chain	Residue
CA	U596
CA	MG724

site_id	AE6
Number of Residues	1
Details	binding site for residue MG CA 719

Chain	Residue
CA	G159

site_id	AE7
Number of Residues	2
Details	binding site for residue MG CA 720

Chain	Residue
CA	C238
CA	U241

site_id	AE8
Number of Residues	3
Details	binding site for residue MG CA 721

Chain	Residue
CA	A583
CA	G584
CA	U588

site_id	AE9
Number of Residues	5
Details	binding site for residue MG CA 722

Chain	Residue
CA	G584
CA	A587
CA	U588
CA	A590
CA	A591

site_id	AF1
Number of Residues	4
Details	binding site for residue MG CA 723

Chain	Residue
CA	A583
CA	G584
CA	A591
CA	A604

site_id	AF2
Number of Residues	1
Details	binding site for residue MG CA 724

Chain	Residue
CA	MG718

site_id	AF3
Number of Residues	3
Details	binding site for residue MG CA 725

Chain	Residue
CA	A222
CA	A224
CA	A225

site_id	AF4
Number of Residues	3
Details	binding site for residue MG CA 728

Chain	Residue
CA	A586
CA	U613
Cb	TYR9

site_id	AF5
Number of Residues	2
Details	binding site for residue MG CA 729

Chain	Residue
CA	A386
CA	U387

site_id	AF6
Number of Residues	2
Details	binding site for residue MG CA 730

Chain	Residue
CA	A385
CA	U544

site_id	AF7
Number of Residues	2
Details	binding site for residue MG CA 731

Chain	Residue
CA	A541
Cm	ASP68

site_id	AF8
Number of Residues	3
Details	binding site for residue MG CA 732

Chain	Residue
CA	A75
CA	A76
Cj	ARG10

site_id	AF9
Number of Residues	7
Details	binding site for residue SPD CA 733

Chain	Residue
CA	A218
CA	U261
CA	A262
CA	A264
Ca	ARG572
Ca	ASP578
Cp	PRO15

site_id	AG1
Number of Residues	8
Details	binding site for residue SPD CA 734

Chain	Residue
Cp	THR12
CA	A27
CA	G239
CA	A266
CA	U267
CA	U268
CL	GLY124
Cp	ASP10

site_id	AG2
Number of Residues	8
Details	binding site for residue SPM CA 735

Chain	Residue
CA	U66
CA	U67
CA	U95
CA	U96
CA	U126
CA	G127
CA	A128
CQ	THR127

Functional Information from PROSITE/UniProt

site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WInspRGQSwAL

Chain	Residue	Details
DM	TRP186-LEU197

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)