Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue GLU A 301 |
| Chain | Residue |
| A | TYR61 |
| A | HOH453 |
| A | HOH457 |
| A | HOH498 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue BR A 302 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue BR A 303 |
| Chain | Residue |
| A | THR93 |
| A | VAL95 |
| A | HOH574 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 305 |
| Chain | Residue |
| A | SER217 |
| A | LYS218 |
| A | HOH441 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue GLU B 301 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR143 |
| B | GLU193 |
| B | HOH413 |
| B | HOH476 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue BR B 303 |
| Chain | Residue |
| B | THR93 |
| B | HOH471 |
| B | HOH608 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue BR B 304 |
| Chain | Residue |
| B | SER108 |
| B | HOH489 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 305 |
| Chain | Residue |
| B | ARG182 |
| B | ILE200 |
| B | ARG203 |
| B | PRO205 |
| B | HOH484 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 306 |
| Chain | Residue |
| B | ASN242 |
| B | HOH424 |
| B | HOH499 |
| B | HOH573 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 307 |
| Chain | Residue |
| B | ASN214 |
| B | LEU215 |
| B | ASP216 |
| B | SER217 |
| B | HOH508 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU193 | |
| B | TYR61 | |
| B | ARG96 | |
| B | GLU193 | |
| A | TYR61 | |
| A | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | PRO89 | |
| B | PRO89 | |
| Chain | Residue | Details |
| B | SER142 | |
| B | THR143 | |
| A | THR91 | |
| A | SER142 | |
| A | THR143 | |
| B | THR91 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| B | ARG64 | |
| B | ARG148 | |
| B | LYS240 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| B | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| B | ASN3 | |
