6GGN

In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue EYH A 201

Chain	Residue
A	LEU54
A	GLY58
A	TYR67
A	GLN72
A	VAL93
A	HIS96
A	ILE99
A	TYR100
A	HOH319

---

site_id	AC2
Number of Residues	8
Details	binding site for residue CL A 202

Chain	Residue
A	TYR60
A	LYS64
A	LYS64
A	ASP80
A	ASP80
A	LEU81
A	LEU81
A	HOH324

---