6CTD
C-terminal domain truncation of the Mycobacterium tuberculosis Mechanosensitive Channel of Large Conductance MscL
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| D | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
| D | 0034220 | biological_process | monoatomic ion transmembrane transport |
| E | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| E | 0016020 | cellular_component | membrane |
| E | 0034220 | biological_process | monoatomic ion transmembrane transport |
| F | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| F | 0016020 | cellular_component | membrane |
| F | 0034220 | biological_process | monoatomic ion transmembrane transport |
| G | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| G | 0016020 | cellular_component | membrane |
| G | 0034220 | biological_process | monoatomic ion transmembrane transport |
| H | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| H | 0016020 | cellular_component | membrane |
| H | 0034220 | biological_process | monoatomic ion transmembrane transport |
| I | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| I | 0016020 | cellular_component | membrane |
| I | 0034220 | biological_process | monoatomic ion transmembrane transport |
| J | 0008381 | molecular_function | mechanosensitive monoatomic ion channel activity |
| J | 0016020 | cellular_component | membrane |
| J | 0034220 | biological_process | monoatomic ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue AU F 201 |
| Chain | Residue |
| F | GLY62 |
| F | GLY63 |
| F | GLY64 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue AU G 201 |
| Chain | Residue |
| G | GLY63 |
| G | GLY64 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue AU H 201 |
| Chain | Residue |
| B | GLY63 |
| H | GLY63 |
| H | GLY64 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue AU I 201 |
| Chain | Residue |
| I | GLY63 |
| I | GLY64 |
| I | GLY62 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue AU J 201 |
| Chain | Residue |
| J | GLY63 |
| J | GLY64 |
Functional Information from PROSITE/UniProt
| site_id | PS01327 |
| Number of Residues | 14 |
| Details | MSCL Large-conductance mechanosensitive channels mscL family signature. RGNIVDLAVAVVIG |
| Chain | Residue | Details |
| A | ARG11-GLY24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 130 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:9856938 |
| Chain | Residue | Details |
| A | MET1-ILE14 | |
| B | MET1-ILE14 | |
| C | MET1-ILE14 | |
| D | MET1-ILE14 | |
| E | MET1-ILE14 | |
| F | MET1-ILE14 | |
| G | MET1-ILE14 | |
| H | MET1-ILE14 | |
| I | MET1-ILE14 | |
| J | MET1-ILE14 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 480 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:9856938 |
| Chain | Residue | Details |
| A | VAL15-ILE43 | |
| A | LEU69-LEU89 | |
| B | VAL15-ILE43 | |
| B | LEU69-LEU89 | |
| C | VAL15-ILE43 | |
| C | LEU69-LEU89 | |
| D | VAL15-ILE43 | |
| D | LEU69-LEU89 | |
| E | VAL15-ILE43 | |
| E | LEU69-LEU89 | |
| F | VAL15-ILE43 | |
| F | LEU69-LEU89 | |
| G | VAL15-ILE43 | |
| G | LEU69-LEU89 | |
| H | LEU69-LEU89 | |
| I | VAL15-ILE43 | |
| I | LEU69-LEU89 | |
| J | VAL15-ILE43 | |
| J | LEU69-LEU89 | |
| H | VAL15-ILE43 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 240 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:9856938 |
| Chain | Residue | Details |
| A | ASN44-ASP68 | |
| B | ASN44-ASP68 | |
| C | ASN44-ASP68 | |
| D | ASN44-ASP68 | |
| E | ASN44-ASP68 | |
| F | ASN44-ASP68 | |
| G | ASN44-ASP68 | |
| H | ASN44-ASP68 | |
| I | ASN44-ASP68 | |
| J | ASN44-ASP68 |
