Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004032 | molecular_function | aldose reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0032866 | molecular_function | D-xylose reductase (NADPH) activity |
| A | 0042843 | biological_process | D-xylose catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | binding site for residues NDP A 400 and DTT A 401 |
| Chain | Residue |
| A | ARG-4 |
| A | HIS109 |
| A | PHE110 |
| A | SER164 |
| A | ASN165 |
| A | GLN186 |
| A | TYR212 |
| A | SER213 |
| A | SER214 |
| A | PHE215 |
| A | GLN218 |
| A | GLY17 |
| A | SER219 |
| A | PHE235 |
| A | ALA252 |
| A | ILE267 |
| A | PRO268 |
| A | LYS269 |
| A | SER270 |
| A | ASN271 |
| A | ARG275 |
| A | ASN279 |
| A | CYS18 |
| A | ASN305 |
| A | HOH509 |
| A | HOH536 |
| A | HOH599 |
| A | HOH604 |
| A | HOH610 |
| A | HOH685 |
| A | TRP19 |
| A | ASP42 |
| A | ASP46 |
| A | TYR47 |
| A | LYS76 |
| A | TRP78 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. MekltkggkAKSIGISNF |
| Chain | Residue | Details |
| A | MET149-PHE166 | |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. IPKSNNpdRLlQNlEV |
| Chain | Residue | Details |
| A | ILE267-VAL282 | |
| site_id | PS00163 |
| Number of Residues | 10 |
| Details | FUMARATE_LYASES Fumarate lyases signature. GShmMsIKlN |
| Chain | Residue | Details |
| A | GLY-3-ASN6 | |
