5Z5C
Crystal structure of hydrogen sulfide-producing enzyme (Fn1055) from Fusobacterium nucleatum: lysine-dimethylated form
Replaces: 5B54Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006534 | biological_process | cysteine metabolic process |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0009069 | biological_process | serine family amino acid metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0044272 | biological_process | sulfur compound biosynthetic process |
| A | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006534 | biological_process | cysteine metabolic process |
| B | 0006535 | biological_process | cysteine biosynthetic process from serine |
| B | 0009069 | biological_process | serine family amino acid metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0044272 | biological_process | sulfur compound biosynthetic process |
| B | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| C | 0004124 | molecular_function | cysteine synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006534 | biological_process | cysteine metabolic process |
| C | 0006535 | biological_process | cysteine biosynthetic process from serine |
| C | 0009069 | biological_process | serine family amino acid metabolic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0044272 | biological_process | sulfur compound biosynthetic process |
| C | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
| D | 0004124 | molecular_function | cysteine synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006534 | biological_process | cysteine metabolic process |
| D | 0006535 | biological_process | cysteine biosynthetic process from serine |
| D | 0009069 | biological_process | serine family amino acid metabolic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0044272 | biological_process | sulfur compound biosynthetic process |
| D | 0080146 | molecular_function | L-cysteine desulfhydrase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | LYS46 |
| A | GLU228 |
| A | GLY229 |
| A | ILE230 |
| A | SER272 |
| A | PRO298 |
| A | ASP299 |
| A | HOH516 |
| A | HOH548 |
| A | HOH552 |
| A | HOH558 |
| A | ASN76 |
| A | GLY182 |
| A | VAL183 |
| A | GLY184 |
| A | THR185 |
| A | GLY186 |
| A | GLY187 |
| A | THR188 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | LYS46 |
| A | THR73 |
| A | SER74 |
| A | THR77 |
| A | GLN147 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL C 402 |
| Chain | Residue |
| C | LYS46 |
| C | THR73 |
| C | SER74 |
| C | THR77 |
| C | GLN147 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 402 |
| Chain | Residue |
| D | LYS46 |
| D | THR73 |
| D | SER74 |
| D | THR77 |
| D | GLN147 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | binding site for Di-peptide PLP B 401 and LYS B 46 |
| Chain | Residue |
| B | SER44 |
| B | ILE45 |
| B | ASP47 |
| B | ARG48 |
| B | MET49 |
| B | ALA50 |
| B | ASN76 |
| B | THR77 |
| B | ALA80 |
| B | VAL183 |
| B | GLY184 |
| B | THR185 |
| B | GLY186 |
| B | GLY187 |
| B | THR188 |
| B | GLY229 |
| B | ILE230 |
| B | SER272 |
| B | PRO298 |
| B | ASP299 |
| B | HOH501 |
| B | HOH530 |
| B | HOH540 |
| B | HOH553 |
| site_id | AC6 |
| Number of Residues | 27 |
| Details | binding site for Di-peptide PLP C 401 and LYS C 46 |
| Chain | Residue |
| C | SER44 |
| C | ILE45 |
| C | ASP47 |
| C | ARG48 |
| C | MET49 |
| C | ALA50 |
| C | ASN76 |
| C | THR77 |
| C | GLY182 |
| C | VAL183 |
| C | GLY184 |
| C | THR185 |
| C | GLY186 |
| C | GLY187 |
| C | THR188 |
| C | GLU228 |
| C | GLY229 |
| C | ILE230 |
| C | SER272 |
| C | PRO298 |
| C | ASP299 |
| C | TYR304 |
| C | CL402 |
| C | HOH516 |
| C | HOH538 |
| C | HOH553 |
| C | HOH564 |
| site_id | AC7 |
| Number of Residues | 26 |
| Details | binding site for Di-peptide PLP D 401 and LYS D 46 |
| Chain | Residue |
| D | THR188 |
| D | GLY229 |
| D | ILE230 |
| D | SER272 |
| D | PRO298 |
| D | ASP299 |
| D | TYR304 |
| D | CL402 |
| D | HOH506 |
| D | HOH513 |
| D | HOH542 |
| D | HOH569 |
| D | SER44 |
| D | ILE45 |
| D | ASP47 |
| D | ARG48 |
| D | MET49 |
| D | ALA50 |
| D | ASN76 |
| D | THR77 |
| D | GLY182 |
| D | VAL183 |
| D | GLY184 |
| D | THR185 |
| D | GLY186 |
| D | GLY187 |
