5WSL
Structural studies of keratinase from Meiothermus taiwanensis WR-220
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0019538 | biological_process | protein metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0019538 | biological_process | protein metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0005615 | cellular_component | extracellular space |
| C | 0006508 | biological_process | proteolysis |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0019538 | biological_process | protein metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | ASP11 |
| A | ASP14 |
| A | GLN15 |
| A | SER21 |
| A | THR23 |
| A | HOH517 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 302 |
| Chain | Residue |
| A | THR177 |
| A | ASP198 |
| A | HOH401 |
| A | HOH475 |
| A | VAL172 |
| A | THR173 |
| A | GLY175 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | GLN15 |
| A | ARG16 |
| A | THR17 |
| A | TYR275 |
| A | HOH403 |
| A | HOH424 |
| A | HOH450 |
| A | HOH545 |
| C | SER137 |
| C | ALA138 |
| C | HOH426 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | SER137 |
| A | ALA138 |
| A | HOH409 |
| A | HOH420 |
| A | HOH536 |
| B | GLN15 |
| B | ARG16 |
| B | THR17 |
| B | TYR275 |
| B | HOH412 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | ARG162 |
| B | ALA1 |
| B | THR2 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | THR182 |
| A | ALA188 |
| A | SER189 |
| A | SER204 |
| A | HOH423 |
| A | HOH432 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 301 |
| Chain | Residue |
| B | ASP11 |
| B | ASP14 |
| B | GLN15 |
| B | SER21 |
| B | THR23 |
| B | HOH542 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 302 |
| Chain | Residue |
| B | VAL172 |
| B | THR173 |
| B | GLY175 |
| B | THR177 |
| B | ASP198 |
| B | HOH402 |
| B | HOH491 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| A | SER212 |
| A | SER213 |
| A | SER216 |
| B | SER213 |
| B | THR215 |
| B | SER216 |
| B | HOH405 |
| B | HOH437 |
| B | HOH438 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| B | SER137 |
| B | ALA138 |
| B | HOH414 |
| B | HOH415 |
| B | HOH463 |
| B | HOH521 |
| C | GLN15 |
| C | ARG16 |
| C | THR17 |
| C | TYR275 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | ARG162 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 306 |
| Chain | Residue |
| B | ALA188 |
| B | SER189 |
| B | TYR190 |
| B | SER204 |
| B | HOH436 |
| B | HOH453 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 301 |
| Chain | Residue |
| C | ASP11 |
| C | ASP14 |
| C | GLN15 |
| C | SER21 |
| C | THR23 |
| C | HOH499 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 302 |
| Chain | Residue |
| C | VAL172 |
| C | THR173 |
| C | GLY175 |
| C | THR177 |
| C | ASP198 |
| C | HOH402 |
| C | HOH460 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 303 |
| Chain | Residue |
| C | HOH408 |
| C | HOH551 |
| C | SER212 |
| C | SER213 |
| C | SER216 |
| C | HOH403 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. AYIIDTGIrvsH |
| Chain | Residue | Details |
| A | ALA35-HIS46 |
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThVAGtVGG |
| Chain | Residue | Details |
| A | HIS72-GLY82 |
| site_id | PS00138 |
| Number of Residues | 11 |
| Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAtPhVAG |
| Chain | Residue | Details |
| A | GLY222-GLY232 |
