5WMB

Structure of the 10S (-)-cis-BP-dG modified Rev1 ternary complex (the BP residue is disordered)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MG P 101

Chain	Residue
A	ASP548
A	LEU550
A	VAL553
A	HOH934
P	DA11
P	HOH204

---

site_id	AC2
Number of Residues	7
Details	binding site for residue MG A 801

Chain	Residue
A	MG802
A	MG803
A	DCP804
P	DDG12
A	ASP362
A	ASP467
A	GLU468

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 802

Chain	Residue
A	ASP362
A	PHE363
A	ASP467
A	MG801
A	MG803
A	DCP804

---

site_id	AC4
Number of Residues	8
Details	binding site for residue MG A 803

Chain	Residue
A	ASP362
A	LYS525
A	MG801
A	MG802
A	DCP804
A	HOH980
A	HOH1004
A	HOH1026

---

site_id	AC5
Number of Residues	21
Details	binding site for residue DCP A 804

Chain	Residue
A	ARG324
A	LEU328
A	ASP362
A	PHE363
A	ASP364
A	CYS365
A	PHE366
A	PHE367
A	ALA401
A	SER402
A	TYR405
A	ARG408
A	ASN414
A	ASP467
A	LYS525
A	MG801
A	MG802
A	MG803
A	HOH928
A	HOH980
P	DDG12

---

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL A 805

Chain	Residue
A	THR355
A	TYR356
A	ASP512
A	LYS534
A	HOH978

---

site_id	AC7
Number of Residues	6
Details	binding site for residue GOL A 806

Chain	Residue
A	ARG494
A	GLN495
A	THR505
A	ASN527
A	HOH951
A	HOH969

---

site_id	AC8
Number of Residues	6
Details	binding site for residue GOL A 807

Chain	Residue
A	LEU335
A	GLU342
A	TYR449
A	LYS453
A	ILE461
A	PRO463

---

site_id	AC9
Number of Residues	10
Details	binding site for residue GOL A 808

Chain	Residue
A	ILE457
A	ASN459
A	ARG473
A	ILE474
A	SER543
A	SER570
A	ASN572
A	ASP573
A	LYS576
A	HOH906

---

site_id	AD1
Number of Residues	2
Details	binding site for residue EDO A 809

Chain	Residue
A	SER544
A	ASP549

---

site_id	AD2
Number of Residues	1
Details	binding site for residue EDO A 810

Chain	Residue
A	ASP352

---

site_id	AD3
Number of Residues	5
Details	binding site for residue EDO A 811

Chain	Residue
A	ASN334
A	LEU335
A	SER445
A	GLU446
A	HOH1003

---

site_id	AD4
Number of Residues	3
Details	binding site for residue EDO A 812

Chain	Residue
A	THR482
A	PHE533
A	SER535

---

site_id	AD5
Number of Residues	6
Details	binding site for residue EDO A 813

Chain	Residue
A	CYS365
A	PHE384
A	ASN527
A	HOH903
A	HOH919
A	HOH991

---

site_id	AD6
Number of Residues	2
Details	binding site for residue EDO A 814

Chain	Residue
A	ASN502
A	HOH993

---

site_id	AD7
Number of Residues	4
Details	binding site for residue EDO A 815

Chain	Residue
A	VAL308
A	SER318
A	TYR319
T	DC4

---

site_id	AD8
Number of Residues	6
Details	binding site for residue PEG A 816

Chain	Residue
A	SER695
A	ARG696
A	GLU710
A	HOH955
A	HOH995
A	ASP566

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:16195463, ECO:0000269|PubMed:18275815

Chain	Residue	Details
A	ASN414
A	ARG324
A	SER402

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00216, ECO:0000269|PubMed:18275815

Chain	Residue	Details
A	PHE363
A	ASP467
A	GLU468
A	ASP362

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	SITE: Interaction with target DNA

Chain	Residue	Details
A	SER692
A	SER694
A	LYS681

---