5WDX

Structure of NS3 from HCV strain JFH-1 that is an unusually robust helicase that is primed to bind and unwind viral RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0019087	biological_process	transformation of host cell by virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 701

Chain	Residue
A	CYS97
A	CYS99
A	CYS145
A	HIS149

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site_id	AC2
Number of Residues	4
Details	binding site for residue MG A 702

Chain	Residue
A	GLY209
A	LYS210
A	SER211
A	THR212

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site_id	AC3
Number of Residues	4
Details	binding site for residue MG A 703

Chain	Residue
A	LYS210
A	HIS293
A	ALA323
A	THR206

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