Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5VOY

Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity
A	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
A	0046034	biological_process	ATP metabolic process
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0000139	cellular_component	Golgi membrane
B	0000166	molecular_function	nucleotide binding
B	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
B	0000329	cellular_component	fungal-type vacuole membrane
B	0000425	biological_process	pexophagy
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005773	cellular_component	vacuole
B	0005774	cellular_component	vacuolar membrane
B	0006811	biological_process	monoatomic ion transport
B	0006874	biological_process	intracellular calcium ion homeostasis
B	0007035	biological_process	vacuolar acidification
B	0010494	cellular_component	cytoplasmic stress granule
B	0016020	cellular_component	membrane
B	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
B	0033176	cellular_component	proton-transporting V-type ATPase complex
B	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
B	0046034	biological_process	ATP metabolic process
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	0048388	biological_process	endosomal lumen acidification
B	0055085	biological_process	transmembrane transport
B	0061795	biological_process	Golgi lumen acidification
B	1902600	biological_process	proton transmembrane transport
B	1902906	biological_process	proteasome storage granule assembly
B	1990816	cellular_component	vacuole-mitochondrion membrane contact site
C	0005524	molecular_function	ATP binding
C	0016887	molecular_function	ATP hydrolysis activity
C	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
C	0046034	biological_process	ATP metabolic process
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0000139	cellular_component	Golgi membrane
D	0000166	molecular_function	nucleotide binding
D	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
D	0000329	cellular_component	fungal-type vacuole membrane
D	0000425	biological_process	pexophagy
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005773	cellular_component	vacuole
D	0005774	cellular_component	vacuolar membrane
D	0006811	biological_process	monoatomic ion transport
D	0006874	biological_process	intracellular calcium ion homeostasis
D	0007035	biological_process	vacuolar acidification
D	0010494	cellular_component	cytoplasmic stress granule
D	0016020	cellular_component	membrane
D	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
D	0033176	cellular_component	proton-transporting V-type ATPase complex
D	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
D	0046034	biological_process	ATP metabolic process
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	0048388	biological_process	endosomal lumen acidification
D	0055085	biological_process	transmembrane transport
D	0061795	biological_process	Golgi lumen acidification
D	1902600	biological_process	proton transmembrane transport
D	1902906	biological_process	proteasome storage granule assembly
D	1990816	cellular_component	vacuole-mitochondrion membrane contact site
E	0005524	molecular_function	ATP binding
E	0016887	molecular_function	ATP hydrolysis activity
E	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
E	0046034	biological_process	ATP metabolic process
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0000139	cellular_component	Golgi membrane
F	0000166	molecular_function	nucleotide binding
F	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
F	0000329	cellular_component	fungal-type vacuole membrane
F	0000425	biological_process	pexophagy
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005773	cellular_component	vacuole
F	0005774	cellular_component	vacuolar membrane
F	0006811	biological_process	monoatomic ion transport
F	0006874	biological_process	intracellular calcium ion homeostasis
F	0007035	biological_process	vacuolar acidification
F	0010494	cellular_component	cytoplasmic stress granule
F	0016020	cellular_component	membrane
F	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
F	0033176	cellular_component	proton-transporting V-type ATPase complex
F	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
F	0046034	biological_process	ATP metabolic process
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	0048388	biological_process	endosomal lumen acidification
F	0055085	biological_process	transmembrane transport
F	0061795	biological_process	Golgi lumen acidification
F	1902600	biological_process	proton transmembrane transport
F	1902906	biological_process	proteasome storage granule assembly
F	1990816	cellular_component	vacuole-mitochondrion membrane contact site
G	0000139	cellular_component	Golgi membrane
G	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
G	0000329	cellular_component	fungal-type vacuole membrane
G	0005515	molecular_function	protein binding
G	0005773	cellular_component	vacuole
G	0005774	cellular_component	vacuolar membrane
G	0006811	biological_process	monoatomic ion transport
G	0007035	biological_process	vacuolar acidification
G	0016020	cellular_component	membrane
G	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
G	0033176	cellular_component	proton-transporting V-type ATPase complex
G	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	0048388	biological_process	endosomal lumen acidification
G	0061795	biological_process	Golgi lumen acidification
G	1902600	biological_process	proton transmembrane transport
H	0000139	cellular_component	Golgi membrane
H	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
H	0000329	cellular_component	fungal-type vacuole membrane
H	0005515	molecular_function	protein binding
H	0005773	cellular_component	vacuole
H	0005774	cellular_component	vacuolar membrane
H	0006811	biological_process	monoatomic ion transport
H	0007035	biological_process	vacuolar acidification
H	0016020	cellular_component	membrane
H	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
H	0016887	molecular_function	ATP hydrolysis activity
H	0033176	cellular_component	proton-transporting V-type ATPase complex
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	0048388	biological_process	endosomal lumen acidification
H	0061795	biological_process	Golgi lumen acidification
H	1902600	biological_process	proton transmembrane transport
I	0000139	cellular_component	Golgi membrane
I	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
I	0000329	cellular_component	fungal-type vacuole membrane
I	0005515	molecular_function	protein binding
I	0005773	cellular_component	vacuole
I	0005774	cellular_component	vacuolar membrane
I	0006811	biological_process	monoatomic ion transport
I	0007035	biological_process	vacuolar acidification
I	0016020	cellular_component	membrane
I	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
I	0033176	cellular_component	proton-transporting V-type ATPase complex
I	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	0048388	biological_process	endosomal lumen acidification
I	0061795	biological_process	Golgi lumen acidification
I	1902600	biological_process	proton transmembrane transport
J	0000139	cellular_component	Golgi membrane
J	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
J	0000329	cellular_component	fungal-type vacuole membrane
J	0005515	molecular_function	protein binding
J	0005773	cellular_component	vacuole
J	0005774	cellular_component	vacuolar membrane
J	0006811	biological_process	monoatomic ion transport
J	0007035	biological_process	vacuolar acidification
J	0016020	cellular_component	membrane
J	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
J	0016887	molecular_function	ATP hydrolysis activity
J	0033176	cellular_component	proton-transporting V-type ATPase complex
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	0048388	biological_process	endosomal lumen acidification
J	0061795	biological_process	Golgi lumen acidification
J	1902600	biological_process	proton transmembrane transport
K	0000139	cellular_component	Golgi membrane
K	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
K	0000329	cellular_component	fungal-type vacuole membrane
K	0005515	molecular_function	protein binding
K	0005773	cellular_component	vacuole
K	0005774	cellular_component	vacuolar membrane
K	0006811	biological_process	monoatomic ion transport
K	0007035	biological_process	vacuolar acidification
K	0016020	cellular_component	membrane
K	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
K	0033176	cellular_component	proton-transporting V-type ATPase complex
K	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
K	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
K	0048388	biological_process	endosomal lumen acidification
K	0061795	biological_process	Golgi lumen acidification
K	1902600	biological_process	proton transmembrane transport
L	0000139	cellular_component	Golgi membrane
L	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
L	0000329	cellular_component	fungal-type vacuole membrane
L	0005515	molecular_function	protein binding
L	0005773	cellular_component	vacuole
L	0005774	cellular_component	vacuolar membrane
L	0006811	biological_process	monoatomic ion transport
L	0007035	biological_process	vacuolar acidification
L	0016020	cellular_component	membrane
L	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
L	0016887	molecular_function	ATP hydrolysis activity
L	0033176	cellular_component	proton-transporting V-type ATPase complex
L	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
L	0048388	biological_process	endosomal lumen acidification
L	0061795	biological_process	Golgi lumen acidification
L	1902600	biological_process	proton transmembrane transport
M	0000139	cellular_component	Golgi membrane
M	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
M	0000329	cellular_component	fungal-type vacuole membrane
M	0005515	molecular_function	protein binding
M	0005773	cellular_component	vacuole
M	0005774	cellular_component	vacuolar membrane
M	0006811	biological_process	monoatomic ion transport
M	0007035	biological_process	vacuolar acidification
M	0016020	cellular_component	membrane
M	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
M	0033176	cellular_component	proton-transporting V-type ATPase complex
M	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
M	0048388	biological_process	endosomal lumen acidification
M	0061795	biological_process	Golgi lumen acidification
M	1902600	biological_process	proton transmembrane transport
N	0000139	cellular_component	Golgi membrane
N	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
N	0000329	cellular_component	fungal-type vacuole membrane
N	0005515	molecular_function	protein binding
N	0005773	cellular_component	vacuole
N	0005774	cellular_component	vacuolar membrane
N	0006811	biological_process	monoatomic ion transport
N	0007035	biological_process	vacuolar acidification
N	0016020	cellular_component	membrane
N	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
N	0033176	cellular_component	proton-transporting V-type ATPase complex
N	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
N	0034220	biological_process	monoatomic ion transmembrane transport
N	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
N	0048388	biological_process	endosomal lumen acidification
N	0061795	biological_process	Golgi lumen acidification
N	1902600	biological_process	proton transmembrane transport
O	0000139	cellular_component	Golgi membrane
O	0000166	molecular_function	nucleotide binding
O	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
O	0000329	cellular_component	fungal-type vacuole membrane
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005773	cellular_component	vacuole
O	0005774	cellular_component	vacuolar membrane
O	0006811	biological_process	monoatomic ion transport
O	0007035	biological_process	vacuolar acidification
O	0015078	molecular_function	proton transmembrane transporter activity
O	0016020	cellular_component	membrane
O	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
O	0033176	cellular_component	proton-transporting V-type ATPase complex
O	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
O	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
O	0048388	biological_process	endosomal lumen acidification
O	0061795	biological_process	Golgi lumen acidification
O	1902600	biological_process	proton transmembrane transport
P	0000139	cellular_component	Golgi membrane
P	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
P	0000329	cellular_component	fungal-type vacuole membrane
P	0005515	molecular_function	protein binding
P	0005773	cellular_component	vacuole
P	0005774	cellular_component	vacuolar membrane
P	0006811	biological_process	monoatomic ion transport
P	0007035	biological_process	vacuolar acidification
P	0016020	cellular_component	membrane
P	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
P	0033176	cellular_component	proton-transporting V-type ATPase complex
P	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
P	0048388	biological_process	endosomal lumen acidification
P	0061795	biological_process	Golgi lumen acidification
P	1902600	biological_process	proton transmembrane transport
Q	0000139	cellular_component	Golgi membrane
Q	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
Q	0000329	cellular_component	fungal-type vacuole membrane
Q	0005515	molecular_function	protein binding
Q	0005769	cellular_component	early endosome
Q	0005773	cellular_component	vacuole
Q	0005774	cellular_component	vacuolar membrane
Q	0006811	biological_process	monoatomic ion transport
Q	0007034	biological_process	vacuolar transport
Q	0007035	biological_process	vacuolar acidification
Q	0016020	cellular_component	membrane
Q	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
Q	0033176	cellular_component	proton-transporting V-type ATPase complex
Q	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
Q	0033181	cellular_component	plasma membrane proton-transporting V-type ATPase complex
Q	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
Q	0048388	biological_process	endosomal lumen acidification
Q	0061795	biological_process	Golgi lumen acidification
Q	1902600	biological_process	proton transmembrane transport
R	0000139	cellular_component	Golgi membrane
R	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
R	0000329	cellular_component	fungal-type vacuole membrane
R	0005773	cellular_component	vacuole
R	0005774	cellular_component	vacuolar membrane
R	0006811	biological_process	monoatomic ion transport
R	0007035	biological_process	vacuolar acidification
R	0008553	molecular_function	P-type proton-exporting transporter activity
R	0015078	molecular_function	proton transmembrane transporter activity
R	0016020	cellular_component	membrane
R	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
R	0033176	cellular_component	proton-transporting V-type ATPase complex
R	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
R	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
R	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
R	0048388	biological_process	endosomal lumen acidification
R	0061795	biological_process	Golgi lumen acidification
R	1902600	biological_process	proton transmembrane transport
S	0000139	cellular_component	Golgi membrane
S	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
S	0000324	cellular_component	fungal-type vacuole
S	0000329	cellular_component	fungal-type vacuole membrane
S	0005773	cellular_component	vacuole
S	0005774	cellular_component	vacuolar membrane
S	0006811	biological_process	monoatomic ion transport
S	0007035	biological_process	vacuolar acidification
S	0015078	molecular_function	proton transmembrane transporter activity
S	0016020	cellular_component	membrane
S	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
S	0033176	cellular_component	proton-transporting V-type ATPase complex
S	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
S	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
S	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
S	0048388	biological_process	endosomal lumen acidification
S	0061795	biological_process	Golgi lumen acidification
S	0071944	cellular_component	cell periphery
S	1902600	biological_process	proton transmembrane transport
T	0000139	cellular_component	Golgi membrane
T	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
T	0000329	cellular_component	fungal-type vacuole membrane
T	0005773	cellular_component	vacuole
T	0005774	cellular_component	vacuolar membrane
T	0006623	biological_process	protein targeting to vacuole
T	0006811	biological_process	monoatomic ion transport
T	0006878	biological_process	intracellular copper ion homeostasis
T	0006879	biological_process	intracellular iron ion homeostasis
T	0006897	biological_process	endocytosis
T	0007033	biological_process	vacuole organization
T	0007035	biological_process	vacuolar acidification
T	0015078	molecular_function	proton transmembrane transporter activity
T	0016020	cellular_component	membrane
T	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
T	0033176	cellular_component	proton-transporting V-type ATPase complex
T	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
T	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
T	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
T	0048388	biological_process	endosomal lumen acidification
T	0061795	biological_process	Golgi lumen acidification
T	1902600	biological_process	proton transmembrane transport
U	0000139	cellular_component	Golgi membrane
U	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
U	0000329	cellular_component	fungal-type vacuole membrane
U	0005773	cellular_component	vacuole
U	0005774	cellular_component	vacuolar membrane
U	0006623	biological_process	protein targeting to vacuole
U	0006811	biological_process	monoatomic ion transport
U	0006878	biological_process	intracellular copper ion homeostasis
U	0006879	biological_process	intracellular iron ion homeostasis
U	0006897	biological_process	endocytosis
U	0007033	biological_process	vacuole organization
U	0007035	biological_process	vacuolar acidification
U	0015078	molecular_function	proton transmembrane transporter activity
U	0016020	cellular_component	membrane
U	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
U	0033176	cellular_component	proton-transporting V-type ATPase complex
U	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
U	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
U	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
U	0048388	biological_process	endosomal lumen acidification
U	0061795	biological_process	Golgi lumen acidification
U	1902600	biological_process	proton transmembrane transport
V	0000139	cellular_component	Golgi membrane
V	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
V	0000329	cellular_component	fungal-type vacuole membrane
V	0005773	cellular_component	vacuole
V	0005774	cellular_component	vacuolar membrane
V	0006623	biological_process	protein targeting to vacuole
V	0006811	biological_process	monoatomic ion transport
V	0006878	biological_process	intracellular copper ion homeostasis
V	0006879	biological_process	intracellular iron ion homeostasis
V	0006897	biological_process	endocytosis
V	0007033	biological_process	vacuole organization
V	0007035	biological_process	vacuolar acidification
V	0015078	molecular_function	proton transmembrane transporter activity
V	0016020	cellular_component	membrane
V	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
V	0033176	cellular_component	proton-transporting V-type ATPase complex
V	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
V	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
V	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
V	0048388	biological_process	endosomal lumen acidification
V	0061795	biological_process	Golgi lumen acidification
V	1902600	biological_process	proton transmembrane transport
W	0000139	cellular_component	Golgi membrane
W	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
W	0000329	cellular_component	fungal-type vacuole membrane
W	0005773	cellular_component	vacuole
W	0005774	cellular_component	vacuolar membrane
W	0006623	biological_process	protein targeting to vacuole
W	0006811	biological_process	monoatomic ion transport
W	0006878	biological_process	intracellular copper ion homeostasis
W	0006879	biological_process	intracellular iron ion homeostasis
W	0006897	biological_process	endocytosis
W	0007033	biological_process	vacuole organization
W	0007035	biological_process	vacuolar acidification
W	0015078	molecular_function	proton transmembrane transporter activity
W	0016020	cellular_component	membrane
W	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
W	0033176	cellular_component	proton-transporting V-type ATPase complex
W	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
W	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
W	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
W	0048388	biological_process	endosomal lumen acidification
W	0061795	biological_process	Golgi lumen acidification
W	1902600	biological_process	proton transmembrane transport
X	0000139	cellular_component	Golgi membrane
X	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
X	0000329	cellular_component	fungal-type vacuole membrane
X	0005773	cellular_component	vacuole
X	0005774	cellular_component	vacuolar membrane
X	0006623	biological_process	protein targeting to vacuole
X	0006811	biological_process	monoatomic ion transport
X	0006878	biological_process	intracellular copper ion homeostasis
X	0006879	biological_process	intracellular iron ion homeostasis
X	0006897	biological_process	endocytosis
X	0007033	biological_process	vacuole organization
X	0007035	biological_process	vacuolar acidification
X	0015078	molecular_function	proton transmembrane transporter activity
X	0016020	cellular_component	membrane
X	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
X	0033176	cellular_component	proton-transporting V-type ATPase complex
X	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
X	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
X	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
X	0048388	biological_process	endosomal lumen acidification
X	0061795	biological_process	Golgi lumen acidification
X	1902600	biological_process	proton transmembrane transport
Y	0000139	cellular_component	Golgi membrane
Y	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
Y	0000329	cellular_component	fungal-type vacuole membrane
Y	0005773	cellular_component	vacuole
Y	0005774	cellular_component	vacuolar membrane
Y	0006623	biological_process	protein targeting to vacuole
Y	0006811	biological_process	monoatomic ion transport
Y	0006878	biological_process	intracellular copper ion homeostasis
Y	0006879	biological_process	intracellular iron ion homeostasis
Y	0006897	biological_process	endocytosis
Y	0007033	biological_process	vacuole organization
Y	0007035	biological_process	vacuolar acidification
Y	0015078	molecular_function	proton transmembrane transporter activity
Y	0016020	cellular_component	membrane
Y	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
Y	0033176	cellular_component	proton-transporting V-type ATPase complex
Y	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
Y	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
Y	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
Y	0048388	biological_process	endosomal lumen acidification
Y	0061795	biological_process	Golgi lumen acidification
Y	1902600	biological_process	proton transmembrane transport
Z	0000139	cellular_component	Golgi membrane
Z	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
Z	0000329	cellular_component	fungal-type vacuole membrane
Z	0005773	cellular_component	vacuole
Z	0005774	cellular_component	vacuolar membrane
Z	0006623	biological_process	protein targeting to vacuole
Z	0006811	biological_process	monoatomic ion transport
Z	0006878	biological_process	intracellular copper ion homeostasis
Z	0006879	biological_process	intracellular iron ion homeostasis
Z	0006897	biological_process	endocytosis
Z	0007033	biological_process	vacuole organization
Z	0007035	biological_process	vacuolar acidification
Z	0015078	molecular_function	proton transmembrane transporter activity
Z	0016020	cellular_component	membrane
Z	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
Z	0033176	cellular_component	proton-transporting V-type ATPase complex
Z	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
Z	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
Z	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
Z	0048388	biological_process	endosomal lumen acidification
Z	0061795	biological_process	Golgi lumen acidification
Z	1902600	biological_process	proton transmembrane transport
a	0000139	cellular_component	Golgi membrane
a	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
a	0000329	cellular_component	fungal-type vacuole membrane
a	0005773	cellular_component	vacuole
a	0005774	cellular_component	vacuolar membrane
a	0006623	biological_process	protein targeting to vacuole
a	0006811	biological_process	monoatomic ion transport
a	0006878	biological_process	intracellular copper ion homeostasis
a	0006879	biological_process	intracellular iron ion homeostasis
a	0006897	biological_process	endocytosis
a	0007033	biological_process	vacuole organization
a	0007035	biological_process	vacuolar acidification
a	0015078	molecular_function	proton transmembrane transporter activity
a	0016020	cellular_component	membrane
a	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
a	0033176	cellular_component	proton-transporting V-type ATPase complex
a	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
a	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
a	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
a	0048388	biological_process	endosomal lumen acidification
a	0061795	biological_process	Golgi lumen acidification
a	1902600	biological_process	proton transmembrane transport
b	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
b	0000324	cellular_component	fungal-type vacuole
b	0000329	cellular_component	fungal-type vacuole membrane
b	0005515	molecular_function	protein binding
b	0005773	cellular_component	vacuole
b	0005774	cellular_component	vacuolar membrane
b	0005886	cellular_component	plasma membrane
b	0006797	biological_process	polyphosphate metabolic process
b	0006811	biological_process	monoatomic ion transport
b	0007035	biological_process	vacuolar acidification
b	0016020	cellular_component	membrane
b	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
b	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
b	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
b	0051117	molecular_function	ATPase binding
b	0065003	biological_process	protein-containing complex assembly
b	0071469	biological_process	cellular response to alkaline pH
b	0071474	biological_process	cellular hyperosmotic response
b	0080025	molecular_function	phosphatidylinositol-3,5-bisphosphate binding
b	1902600	biological_process	proton transmembrane transport
c	0000032	biological_process	cell wall mannoprotein biosynthetic process
c	0000139	cellular_component	Golgi membrane
c	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
c	0000329	cellular_component	fungal-type vacuole membrane
c	0005773	cellular_component	vacuole
c	0005774	cellular_component	vacuolar membrane
c	0006811	biological_process	monoatomic ion transport
c	0007035	biological_process	vacuolar acidification
c	0016020	cellular_component	membrane
c	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
c	0033176	cellular_component	proton-transporting V-type ATPase complex
c	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
c	0033181	cellular_component	plasma membrane proton-transporting V-type ATPase complex
c	0042625	molecular_function	ATPase-coupled ion transmembrane transporter activity
c	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
c	0048388	biological_process	endosomal lumen acidification
c	0055085	biological_process	transmembrane transport
c	0061795	biological_process	Golgi lumen acidification
c	0065003	biological_process	protein-containing complex assembly
c	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PSINTSVSYS

Chain	Residue	Details
A	PRO907-SER916
B	PRO371-SER380

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	TOPO_DOM: Lumenal => ECO:0000305

Chain	Residue	Details
c	MET1-SER3
W	MET1-TYR8
W	CYS75-GLN90
W	ASN151-CYS160
X	MET1-TYR8
X	CYS75-GLN90
X	ASN151-CYS160
Y	MET1-TYR8
Y	CYS75-GLN90
Y	ASN151-CYS160
Z	MET1-TYR8
c	HIS57-GLU73
Z	CYS75-GLN90
Z	ASN151-CYS160
a	MET1-TYR8
a	CYS75-GLN90
a	ASN151-CYS160
b	SER555-PHE572
b	LYS657-THR719
b	SER805-SER840
U	ASN151-CYS160
V	MET1-TYR8
V	CYS75-GLN90
V	ASN151-CYS160

site_id	SWS_FT_FI2
Number of Residues	40
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
c	PHE4-MET24
V	ILE54-VAL74
V	LEU91-GLY112
V	LEU125-LEU150
W	ALA9-GLY31
W	ILE54-VAL74
W	LEU91-GLY112
W	LEU125-LEU150
X	ALA9-GLY31
X	ILE54-VAL74
X	LEU91-GLY112
c	THR36-LEU56
X	LEU125-LEU150
Y	ALA9-GLY31
Y	ILE54-VAL74
Y	LEU91-GLY112
Y	LEU125-LEU150
Z	ALA9-GLY31
Z	ILE54-VAL74
Z	LEU91-GLY112
Z	LEU125-LEU150
a	ALA9-GLY31
b	MET457-THR486
a	ILE54-VAL74
a	LEU91-GLY112
a	LEU125-LEU150
b	TYR535-PHE554
b	ILE573-LYS593
b	LEU637-PHE656
b	ILE720-ALA744
b	GLY766-GLU804
V	ALA9-GLY31

site_id	SWS_FT_FI3
Number of Residues	10
Details	TOPO_DOM: Cytoplasmic => ECO:0000305

Chain	Residue	Details
c	ALA25-SER35
X	ASP113-ARG124
Y	THR32-ASN53
Y	ASP113-ARG124
Z	THR32-ASN53
Z	ASP113-ARG124
a	THR32-ASN53
a	ASP113-ARG124
b	MET487-SER534
b	TRP594-PHE636
b	GLN745-VAL765
V	THR32-ASN53
V	ASP113-ARG124
W	THR32-ASN53
W	ASP113-ARG124
X	THR32-ASN53

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0000269\|Ref.6, ECO:0007744\|PubMed:22814378

Chain	Residue	Details
b	ALA2
U	GLU137
V	GLU137
W	GLU137
X	GLU137
Y	GLU137
Z	GLU137
a	GLU137

site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: Phosphoserine; by ATM or ATR => ECO:0007744\|PubMed:17330950, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
B	SER511
D	SER511
F	SER511

site_id	SWS_FT_FI6
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17330950, ECO:0007744\|PubMed:19779198

Chain	Residue	Details
B	SER515
D	SER515
F	SER515

site_id	SWS_FT_FI7
Number of Residues	9
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744\|PubMed:22106047

Chain	Residue	Details
B	LYS14
B	LYS508
D	LYS14
D	LYS508
F	LYS14
F	LYS508

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
A	CYS738	covalent catalysis
A	SER813	electrostatic stabiliser
A	TRP815	electrostatic stabiliser
A	ALA816	proton shuttle (general acid/base)
A	SER1038	proton shuttle (general acid/base)

site_id	MCSA2
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
C	CYS738	covalent catalysis
C	SER813	electrostatic stabiliser
C	TRP815	electrostatic stabiliser
C	ALA816	proton shuttle (general acid/base)
C	SER1038	proton shuttle (general acid/base)

site_id	MCSA3
Number of Residues	9
Details	M-CSA 508

Chain	Residue	Details
E	CYS738	covalent catalysis
E	SER813	electrostatic stabiliser
E	TRP815	electrostatic stabiliser
E	ALA816	proton shuttle (general acid/base)
E	SER1038	proton shuttle (general acid/base)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)