5VN0
Water-forming NADH oxidase from Lactobacillus brevis (LbNOX) bound to NADH.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 39 |
| Details | binding site for residue FAD A 501 |
| Chain | Residue |
| A | GLY7 |
| A | HIS77 |
| A | ASN78 |
| A | VAL79 |
| A | THR110 |
| A | SER111 |
| A | GLY112 |
| A | SER113 |
| A | CYS131 |
| A | LYS132 |
| A | ILE158 |
| A | THR9 |
| A | PHE242 |
| A | ASN245 |
| A | LEU248 |
| A | GLY278 |
| A | ASP279 |
| A | LEU296 |
| A | ALA297 |
| A | THR298 |
| A | OXY502 |
| A | NAI503 |
| A | HIS10 |
| A | HOH649 |
| A | HOH653 |
| A | HOH669 |
| A | HOH693 |
| A | HOH761 |
| A | HOH845 |
| A | HOH859 |
| B | PHE422 |
| B | GLN423 |
| B | HOH733 |
| A | ALA11 |
| A | GLU32 |
| A | ARG33 |
| A | ASN34 |
| A | SER41 |
| A | CYS42 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue OXY A 502 |
| Chain | Residue |
| A | SER41 |
| A | CYS42 |
| A | FAD501 |
| A | HOH649 |
| site_id | AC3 |
| Number of Residues | 27 |
| Details | binding site for residue NAI A 503 |
| Chain | Residue |
| A | GLY156 |
| A | TYR157 |
| A | ILE158 |
| A | GLU161 |
| A | ASP177 |
| A | ALA178 |
| A | MET179 |
| A | PRO184 |
| A | LYS185 |
| A | TYR186 |
| A | CYS239 |
| A | ILE240 |
| A | GLY241 |
| A | PHE242 |
| A | PRO295 |
| A | LEU296 |
| A | GLY326 |
| A | FAD501 |
| A | HOH633 |
| A | HOH645 |
| A | HOH697 |
| A | HOH721 |
| A | HOH825 |
| A | HOH841 |
| A | HOH863 |
| A | HOH869 |
| B | GLN423 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ARG332 |
| A | MET390 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | PHE14 |
| A | TYR60 |
| A | HOH715 |
| A | HOH798 |
| A | HOH867 |
| site_id | AC6 |
| Number of Residues | 38 |
| Details | binding site for residue FAD B 501 |
| Chain | Residue |
| B | ASN245 |
| B | LEU248 |
| B | GLY278 |
| B | ASP279 |
| B | LEU296 |
| B | ALA297 |
| B | OXY502 |
| B | NAI503 |
| B | HOH631 |
| B | HOH642 |
| B | HOH666 |
| B | HOH673 |
| B | HOH689 |
| B | HOH719 |
| B | HOH741 |
| B | HOH809 |
| A | PHE422 |
| A | GLN423 |
| B | GLY7 |
| B | THR9 |
| B | HIS10 |
| B | ALA11 |
| B | GLU32 |
| B | ARG33 |
| B | ASN34 |
| B | SER41 |
| B | CYS42 |
| B | HIS77 |
| B | ASN78 |
| B | VAL79 |
| B | THR110 |
| B | SER111 |
| B | GLY112 |
| B | SER113 |
| B | CYS131 |
| B | LYS132 |
| B | ILE158 |
| B | PHE242 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue OXY B 502 |
| Chain | Residue |
| B | SER41 |
| B | CYS42 |
| B | FAD501 |
| B | HOH631 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | binding site for residue NAI B 503 |
| Chain | Residue |
| A | GLN423 |
| B | GLY156 |
| B | TYR157 |
| B | ILE158 |
| B | GLU161 |
| B | ASP177 |
| B | ALA178 |
| B | MET179 |
| B | PRO184 |
| B | LYS185 |
| B | TYR186 |
| B | CYS239 |
| B | ILE240 |
| B | GLY241 |
| B | PHE242 |
| B | PRO295 |
| B | LEU296 |
| B | GLY326 |
| B | FAD501 |
| B | HOH636 |
| B | HOH653 |
| B | HOH671 |
| B | HOH693 |
| B | HOH698 |
| B | HOH827 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| A | PRO429 |
| A | HOH796 |
| B | PHE14 |
| B | HOH668 |
| B | HOH672 |
| B | HOH789 |
| B | HOH813 |
| site_id | AD1 |
| Number of Residues | 40 |
| Details | binding site for residue FAD C 501 |
| Chain | Residue |
| C | GLY7 |
| C | THR9 |
| C | HIS10 |
| C | ALA11 |
| C | GLU32 |
| C | ARG33 |
| C | ASN34 |
| C | SER41 |
| C | CYS42 |
| C | HIS77 |
| C | ASN78 |
| C | VAL79 |
| C | THR110 |
| C | SER111 |
| C | GLY112 |
| C | SER113 |
| C | CYS131 |
| C | LYS132 |
| C | ILE158 |
| C | PHE242 |
| C | ASN245 |
| C | LEU248 |
| C | GLY278 |
| C | ASP279 |
| C | LEU296 |
| C | ALA297 |
| C | ALA300 |
| C | OXY502 |
| C | NAI503 |
| C | HOH601 |
| C | HOH611 |
| C | HOH654 |
| C | HOH667 |
| C | HOH676 |
| C | HOH684 |
| C | HOH707 |
| C | HOH769 |
| C | HOH806 |
| D | PHE422 |
| D | GLN423 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue OXY C 502 |
| Chain | Residue |
| C | SER41 |
| C | CYS42 |
| C | FAD501 |
| C | HOH676 |
| site_id | AD3 |
| Number of Residues | 26 |
| Details | binding site for residue NAI C 503 |
| Chain | Residue |
| C | GLY156 |
| C | TYR157 |
| C | ILE158 |
| C | GLU161 |
| C | ASP177 |
| C | ALA178 |
| C | MET179 |
| C | PRO184 |
| C | LYS185 |
| C | TYR186 |
| C | CYS239 |
| C | ILE240 |
| C | GLY241 |
| C | PHE242 |
| C | PRO295 |
| C | LEU296 |
| C | GLY326 |
| C | FAD501 |
| C | HOH630 |
| C | HOH640 |
| C | HOH675 |
| C | HOH693 |
| C | HOH743 |
| C | HOH811 |
| C | HOH831 |
| D | GLN423 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| C | ARG332 |
| C | GLU357 |
| C | MET390 |
| site_id | AD5 |
| Number of Residues | 38 |
| Details | binding site for residue FAD D 501 |
| Chain | Residue |
| C | PHE422 |
| C | GLN423 |
| C | HOH729 |
| D | GLY7 |
| D | THR9 |
| D | HIS10 |
| D | ALA11 |
| D | GLU32 |
| D | ARG33 |
| D | ASN34 |
| D | SER41 |
| D | CYS42 |
| D | HIS77 |
| D | ASN78 |
| D | VAL79 |
| D | THR110 |
| D | SER111 |
| D | GLY112 |
| D | SER113 |
| D | CYS131 |
| D | LYS132 |
| D | ILE158 |
| D | PHE242 |
| D | ASN245 |
| D | LEU248 |
| D | GLY278 |
| D | ASP279 |
| D | LEU296 |
| D | ALA297 |
| D | THR298 |
| D | OXY502 |
| D | NAI503 |
| D | HOH650 |
| D | HOH700 |
| D | HOH702 |
| D | HOH709 |
| D | HOH730 |
| D | HOH825 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue OXY D 502 |
| Chain | Residue |
| C | PHE422 |
| D | SER41 |
| D | CYS42 |
| D | FAD501 |
| D | HOH730 |
| site_id | AD7 |
| Number of Residues | 27 |
| Details | binding site for residue NAI D 503 |
| Chain | Residue |
| C | GLN423 |
| D | GLY156 |
| D | TYR157 |
| D | ILE158 |
| D | GLU161 |
| D | ASP177 |
| D | ALA178 |
| D | MET179 |
| D | PRO184 |
| D | LYS185 |
| D | TYR186 |
| D | CYS239 |
| D | ILE240 |
| D | GLY241 |
| D | PHE242 |
| D | PRO295 |
| D | LEU296 |
| D | GLY326 |
| D | FAD501 |
| D | EDO505 |
| D | HOH617 |
| D | HOH671 |
| D | HOH688 |
| D | HOH689 |
| D | HOH755 |
| D | HOH839 |
| D | HOH847 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 504 |
| Chain | Residue |
| D | ARG332 |
| D | GLU357 |
| D | MET390 |
| D | SER391 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 505 |
| Chain | Residue |
| D | LYS185 |
| D | GLY241 |
| D | PHE242 |
| D | NAI503 |
| site_id | AE1 |
| Number of Residues | 39 |
| Details | binding site for residue FAD E 501 |
| Chain | Residue |
| E | GLY7 |
| E | THR9 |
| E | HIS10 |
| E | ALA11 |
| E | GLU32 |
| E | ARG33 |
| E | ASN34 |
| E | SER41 |
| E | CYS42 |
| E | HIS77 |
| E | ASN78 |
| E | VAL79 |
| E | THR110 |
| E | SER111 |
| E | GLY112 |
| E | SER113 |
| E | CYS131 |
| E | LYS132 |
| E | ILE158 |
| E | PHE242 |
| E | ASN245 |
| E | LEU248 |
| E | GLY278 |
| E | ASP279 |
| E | LEU296 |
| E | ALA297 |
| E | ALA300 |
| E | OXY502 |
| E | NAI503 |
| E | HOH627 |
| E | HOH645 |
| E | HOH648 |
| E | HOH672 |
| E | HOH686 |
| E | HOH709 |
| E | HOH724 |
| E | HOH752 |
| F | PHE422 |
| F | GLN423 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue OXY E 502 |
| Chain | Residue |
| E | SER41 |
| E | CYS42 |
| E | FAD501 |
| E | HOH648 |
| site_id | AE3 |
| Number of Residues | 25 |
| Details | binding site for residue NAI E 503 |
| Chain | Residue |
| E | GLY156 |
| E | TYR157 |
| E | ILE158 |
| E | GLU161 |
| E | ASP177 |
| E | ALA178 |
| E | MET179 |
| E | PRO184 |
| E | LYS185 |
| E | TYR186 |
| E | ILE240 |
| E | GLY241 |
| E | PHE242 |
| E | PRO295 |
| E | LEU296 |
| E | GLY326 |
| E | FAD501 |
| E | HOH652 |
| E | HOH658 |
| E | HOH677 |
| E | HOH679 |
| E | HOH693 |
| E | HOH763 |
| E | HOH805 |
| F | GLN423 |
| site_id | AE4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO E 504 |
| Chain | Residue |
| E | PHE14 |
| E | TYR60 |
| E | HOH640 |
| E | HOH718 |
| E | HOH755 |
| E | HOH776 |
| E | HOH804 |
| F | PRO429 |
| site_id | AE5 |
| Number of Residues | 37 |
| Details | binding site for residue FAD F 501 |
| Chain | Residue |
| E | PHE422 |
| E | GLN423 |
| F | GLY7 |
| F | THR9 |
| F | HIS10 |
| F | ALA11 |
| F | GLU32 |
| F | ARG33 |
| F | ASN34 |
| F | SER41 |
| F | CYS42 |
| F | HIS77 |
| F | ASN78 |
| F | VAL79 |
| F | THR110 |
| F | SER111 |
| F | GLY112 |
| F | SER113 |
| F | CYS131 |
| F | LYS132 |
| F | ILE158 |
| F | PHE242 |
| F | ASN245 |
| F | LEU248 |
| F | GLY278 |
| F | ASP279 |
| F | LEU296 |
| F | ALA297 |
| F | OXY502 |
| F | NAI503 |
| F | HOH621 |
| F | HOH623 |
| F | HOH637 |
| F | HOH669 |
| F | HOH709 |
| F | HOH737 |
| F | HOH741 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue OXY F 502 |
| Chain | Residue |
| F | SER41 |
| F | CYS42 |
| F | FAD501 |
| F | HOH621 |
| site_id | AE7 |
| Number of Residues | 21 |
| Details | binding site for residue NAI F 503 |
| Chain | Residue |
| E | GLN423 |
| F | GLY156 |
| F | TYR157 |
| F | ILE158 |
| F | GLU161 |
| F | ASP177 |
| F | ALA178 |
| F | MET179 |
| F | LYS185 |
| F | TYR186 |
| F | CYS239 |
| F | ILE240 |
| F | GLY241 |
| F | PHE242 |
| F | PRO295 |
| F | LEU296 |
| F | GLY326 |
| F | FAD501 |
| F | HOH628 |
| F | HOH635 |
| F | HOH638 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 504 |
| Chain | Residue |
| E | PRO429 |
| F | PHE14 |
| F | TYR60 |
| F | HOH655 |
| F | HOH673 |
| F | HOH746 |
| F | HOH748 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 505 |
| Chain | Residue |
| E | VAL316 |
| F | ASP413 |
| F | MET417 |
| F | GLN441 |
| F | HOH663 |
| F | HOH716 |
| F | HOH828 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO F 506 |
| Chain | Residue |
| F | ARG332 |
| F | GLU357 |
| F | MET390 |
| site_id | AF2 |
| Number of Residues | 37 |
| Details | binding site for residue FAD G 501 |
| Chain | Residue |
| G | GLY7 |
| G | THR9 |
| G | HIS10 |
| G | ALA11 |
| G | GLU32 |
| G | ARG33 |
| G | ASN34 |
| G | SER41 |
| G | CYS42 |
| G | HIS77 |
| G | ASN78 |
| G | VAL79 |
| G | THR110 |
| G | SER111 |
| G | GLY112 |
| G | SER113 |
| G | CYS131 |
| G | LYS132 |
| G | ILE158 |
| G | PHE242 |
| G | ASN245 |
| G | LEU248 |
| G | GLY278 |
| G | ASP279 |
| G | LEU296 |
| G | ALA297 |
| G | OXY502 |
| G | NAI503 |
| G | HOH628 |
| G | HOH632 |
| G | HOH642 |
| G | HOH677 |
| G | HOH683 |
| G | HOH807 |
| H | PHE422 |
| H | GLN423 |
| H | HOH741 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue OXY G 502 |
| Chain | Residue |
| G | SER41 |
| G | CYS42 |
| G | FAD501 |
| G | HOH642 |
| site_id | AF4 |
| Number of Residues | 23 |
| Details | binding site for residue NAI G 503 |
| Chain | Residue |
| G | GLY156 |
| G | TYR157 |
| G | ILE158 |
| G | GLU161 |
| G | ASP177 |
| G | ALA178 |
| G | MET179 |
| G | LYS185 |
| G | TYR186 |
| G | CYS239 |
| G | ILE240 |
| G | GLY241 |
| G | PHE242 |
| G | PRO295 |
| G | LEU296 |
| G | GLY326 |
| G | FAD501 |
| G | HOH625 |
| G | HOH634 |
| G | HOH651 |
| G | HOH668 |
| G | HOH687 |
| H | GLN423 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO G 504 |
| Chain | Residue |
| G | PHE14 |
| G | TYR60 |
| G | HOH645 |
| G | HOH746 |
| G | HOH752 |
| G | HOH759 |
| H | PRO429 |
| site_id | AF6 |
| Number of Residues | 39 |
| Details | binding site for residue FAD H 501 |
| Chain | Residue |
| G | PHE422 |
| G | GLN423 |
| H | GLY7 |
| H | THR9 |
| H | HIS10 |
| H | ALA11 |
| H | GLU32 |
| H | ARG33 |
| H | ASN34 |
| H | SER41 |
| H | CYS42 |
| H | HIS77 |
| H | ASN78 |
| H | VAL79 |
| H | THR110 |
| H | SER111 |
| H | GLY112 |
| H | SER113 |
| H | CYS131 |
| H | LYS132 |
| H | ILE158 |
| H | PHE242 |
| H | ASN245 |
| H | LEU248 |
| H | GLY278 |
| H | ASP279 |
| H | LEU296 |
| H | ALA297 |
| H | ALA300 |
| H | OXY502 |
| H | NAI503 |
| H | HOH626 |
| H | HOH673 |
| H | HOH679 |
| H | HOH688 |
| H | HOH706 |
| H | HOH723 |
| H | HOH767 |
| H | HOH781 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue OXY H 502 |
| Chain | Residue |
| H | SER41 |
| H | CYS42 |
| H | FAD501 |
| H | HOH673 |
| site_id | AF8 |
| Number of Residues | 23 |
| Details | binding site for residue NAI H 503 |
| Chain | Residue |
| G | GLN423 |
| H | GLY156 |
| H | TYR157 |
| H | ILE158 |
| H | GLU161 |
| H | ASP177 |
| H | ALA178 |
| H | MET179 |
| H | PRO184 |
| H | LYS185 |
| H | TYR186 |
| H | ILE240 |
| H | GLY241 |
| H | PHE242 |
| H | PRO295 |
| H | LEU296 |
| H | GLY326 |
| H | FAD501 |
| H | HOH650 |
| H | HOH659 |
| H | HOH693 |
| H | HOH702 |
| H | HOH800 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO H 504 |
| Chain | Residue |
| G | VAL316 |
| H | ASP413 |
| H | MET417 |
| H | GLN441 |
| H | HOH700 |
| H | HOH842 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO H 505 |
| Chain | Residue |
| H | ARG332 |
| H | GLU357 |
| H | MET390 |
| H | SER391 |
| H | HOH644 |
| H | HOH802 |
