5U7B
Crystal structure of a the tin-bound form of MerB formed from Diethyltin.
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016829 | molecular_function | lyase activity |
A | 0018836 | molecular_function | alkylmercury lyase activity |
A | 0046413 | biological_process | obsolete obsolete organomercury catabolic process |
A | 0046689 | biological_process | response to mercury ion |
B | 0016829 | molecular_function | lyase activity |
B | 0018836 | molecular_function | alkylmercury lyase activity |
B | 0046413 | biological_process | obsolete obsolete organomercury catabolic process |
B | 0046689 | biological_process | response to mercury ion |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue BR A 301 |
Chain | Residue |
A | LYS2 |
A | PRO5 |
B | PRO5 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue ACT A 302 |
Chain | Residue |
A | CYS160 |
A | HIS161 |
A | HIS163 |
A | TRP174 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue ZN6 A 303 |
Chain | Residue |
A | CYS159 |
A | HOH456 |
A | HOH469 |
A | CYS96 |
A | ASP99 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue ACT B 301 |
Chain | Residue |
A | HOH465 |
B | CYS160 |
B | HIS161 |
B | HIS163 |
B | TRP174 |
B | HOH407 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue ZN6 B 302 |
Chain | Residue |
B | CYS96 |
B | ASP99 |
B | CYS159 |
B | HOH455 |
B | HOH458 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 297 |
Chain | Residue | Details |
A | CYS96 | activator, covalently attached, hydrogen bond donor, nucleophile, proton donor |
A | ASP99 | activator, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
A | CYS159 | activator, covalently attached, nucleophile, proton donor |
site_id | MCSA2 |
Number of Residues | 3 |
Details | M-CSA 297 |
Chain | Residue | Details |
B | CYS96 | activator, covalently attached, hydrogen bond donor, nucleophile, proton donor |
B | ASP99 | activator, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
B | CYS159 | activator, covalently attached, nucleophile, proton donor |