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5RXS

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1818332938

Functional Information from GO Data
ChainGOidnamespacecontents
A0016791molecular_functionphosphatase activity
A0046856biological_processphosphatidylinositol dephosphorylation
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue S8G A 901
ChainResidue
ATYR440
AHOH1076
AGLU470
AILE471
ATHR472
ASER473
AARG623
AARG624
AGLU633
AHOH1004

site_idAC2
Number of Residues7
Detailsbinding site for residue S8G A 902
ChainResidue
ATHR478
AVAL479
AGLU498
AILE504
AVAL716
ASER717
ALYS718

site_idAC3
Number of Residues7
Detailsbinding site for residue DMS A 903
ChainResidue
AGLY531
ATHR532
ATHR579
ATHR712
AASP798
AGLN799
AHOH1223

site_idAC4
Number of Residues6
Detailsbinding site for residue DMS A 904
ChainResidue
ATYR679
ASER753
ASER754
AHIS800
ALEU802
AHOH1158

site_idAC5
Number of Residues5
Detailsbinding site for residue DMS A 905
ChainResidue
AHIS576
AHIS631
ACYS818
ATHR834
AHOH1153

221051

PDB entries from 2024-06-12

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