Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | SER163 |
| A | ASP164 |
| A | HOH402 |
| B | ARG331 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| B | HOH709 |
| A | HOH403 |
| A | HOH404 |
| A | HOH443 |
| B | SER453 |
| B | GLU454 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ARG173 |
| A | CYS174 |
| A | TYR178 |
| A | SER179 |
| A | LEU180 |
| A | HOH404 |
| A | HOH418 |
| A | HOH419 |
| A | HOH420 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue 7YA B 501 |
| Chain | Residue |
| B | HIS253 |
| B | CYS254 |
| B | LYS257 |
| B | SER399 |
| B | CYS400 |
| B | LYS401 |
| B | SER404 |
| B | SER423 |
| B | TRP424 |
| B | HOH603 |
| B | HOH616 |
| B | HOH636 |
| B | HOH656 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 502 |
| Chain | Residue |
| B | GLU270 |
| B | ASP272 |
| B | GLU275 |
| B | GLU280 |
| B | HOH688 |
| B | HOH792 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 503 |
| Chain | Residue |
| B | MET366 |
| B | THR367 |
| B | ARG439 |
| B | HOH604 |
| B | HOH618 |
| B | HOH649 |
| B | HOH731 |
| B | HOH779 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| A | TYR193 |
| B | THR315 |
| B | ASP316 |
| B | HIS317 |
| B | HOH637 |
| B | HOH677 |
| B | HOH711 |
| B | HOH773 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| B | GLY458 |
| B | VAL459 |
| B | HOH687 |
| B | HOH692 |
| B | HOH830 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 506 |
| Chain | Residue |
| B | PHE255 |
| B | ASP256 |
| B | TRP261 |
| B | ILE290 |
| B | PRO296 |
| B | HOH605 |
| B | HOH638 |
| B | HOH661 |
Functional Information from PROSITE/UniProt
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| B | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| B | ASP398-ALA409 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| B | HIS253 | |
| B | ASP302 | |
| B | SER404 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| B | ASP398 | |
| Chain | Residue | Details |
| B | ASN382 | |
