5OPM
Crystal structure of D52N/R238W cN-II mutant bound to dATP and free phosphate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue PO4 A 501 |
| Chain | Residue |
| A | ASN52 |
| A | HOH654 |
| A | HOH715 |
| A | HOH806 |
| A | MET53 |
| A | ASP54 |
| A | THR249 |
| A | ASN250 |
| A | SER251 |
| A | LYS292 |
| A | MG502 |
| A | HOH627 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | ASN52 |
| A | ASP54 |
| A | ASP351 |
| A | PO4501 |
| A | HOH627 |
| A | HOH654 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 503 |
| Chain | Residue |
| A | LYS362 |
| A | DTP504 |
| A | DTP504 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue DTP A 504 |
| Chain | Residue |
| A | ARG144 |
| A | ASP145 |
| A | ASN154 |
| A | PHE354 |
| A | LEU358 |
| A | LYS362 |
| A | LYS362 |
| A | GLN453 |
| A | ARG456 |
| A | ARG456 |
| A | TYR457 |
| A | MG503 |
| A | MG503 |
| A | HOH608 |
| A | HOH662 |
| A | HOH796 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | ARG34 |
| A | VAL35 |
| A | VAL37 |
| A | TYR475 |
| A | ARG478 |
| A | HOH825 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | PHE157 |
| A | ARG202 |
| A | VAL205 |
| A | ASP206 |
| A | TYR210 |
| A | HOH666 |
| A | HOH675 |
| A | HOH726 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | LEU119 |
| A | THR427 |
| A | SER443 |
| A | ARG446 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 508 |
| Chain | Residue |
| A | ASP54 |
| A | TYR65 |
| A | PHE157 |
| A | HIS209 |
| A | TYR210 |
| A | LYS215 |
| A | SER251 |
| A | TYR255 |
| A | HOH609 |
| A | HOH647 |
| A | HOH726 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:21396942 |
| Chain | Residue | Details |
| A | ASN52 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000305|PubMed:21396942 |
| Chain | Residue | Details |
| A | ASP54 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17405878, ECO:0000269|PubMed:21396942, ECO:0007744|PDB:2J2C, ECO:0007744|PDB:2JC9, ECO:0007744|PDB:2JCM, ECO:0007744|PDB:2XCV, ECO:0007744|PDB:2XCW, ECO:0007744|PDB:2XJB, ECO:0007744|PDB:2XJC, ECO:0007744|PDB:2XJD, ECO:0007744|PDB:2XJE |
| Chain | Residue | Details |
| A | ASP54 | |
| A | ASN52 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21396942, ECO:0007744|PDB:2XJB |
| Chain | Residue | Details |
| A | SER464 | |
| A | ARG144 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21396942, ECO:0007744|PDB:2XJC |
| Chain | Residue | Details |
| A | LYS362 | |
| A | TYR461 | |
| A | PHE465 | |
| A | ASN154 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21396942, ECO:0007744|PDB:2XCV, ECO:0007744|PDB:2XCW |
| Chain | Residue | Details |
| A | ARG202 | |
| A | ASP206 | |
| A | LYS215 | |
| A | THR249 | |
| A | ASN250 | |
| A | SER251 | |
| A | LYS292 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17405878, ECO:0000269|PubMed:21396942, ECO:0007744|PDB:2J2C, ECO:0007744|PDB:2JC9, ECO:0007744|PDB:2JCM |
| Chain | Residue | Details |
| A | ASP351 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17405878, ECO:0007744|PDB:2JC9 |
| Chain | Residue | Details |
| A | GLY444 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | VAL426 |
