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5OMV

Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0006287biological_processbase-excision repair, gap-filling
A0006297biological_processnucleotide-excision repair, DNA gap filling
A0008296molecular_function3'-5'-DNA exonuclease activity
A0009432biological_processSOS response
A0045004biological_processDNA replication proofreading
A0071897biological_processDNA biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue MN A 801
ChainResidue
AASP404
APHE405
AASP542
ADTP806

site_idAC2
Number of Residues6
Detailsbinding site for residue GOL A 802
ChainResidue
PDC12
ATYR402
AHIS545
ATYR583
ATYR594
AARG606

site_idAC3
Number of Residues7
Detailsbinding site for residue MG A 803
ChainResidue
ATYR402
AASP404
AASP542
ADTP806
AHOH1001
AHOH1031
PDC12

site_idAC4
Number of Residues2
Detailsbinding site for residue PGE A 804
ChainResidue
ATYR273
AHOH1038

site_idAC5
Number of Residues1
Detailsbinding site for residue PGE A 805
ChainResidue
ATYR110

site_idAC6
Number of Residues19
Detailsbinding site for residue DTP A 806
ChainResidue
AASP404
APHE405
ASER407
ALEU408
ATYR409
AARG460
ALYS487
AASN491
AASP542
AMN801
AMG803
AHOH922
AHOH935
AHOH947
AHOH975
AHOH986
PDC12
TDT4
TDG5

site_idAC7
Number of Residues2
Detailsbinding site for residue MG T 101
ChainResidue
AARG97
TDC16

Functional Information from PROSITE/UniProt
site_idPS00116
Number of Residues9
DetailsDNA_POLYMERASE_B DNA polymerase family B signature. YADTDGLHA
ChainResidueDetails
ATYR538-ALA546

219869

PDB entries from 2024-05-15

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