5O32
The structure of complement complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004866 | molecular_function | endopeptidase inhibitor activity |
| B | 0004866 | molecular_function | endopeptidase inhibitor activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| D | 0016020 | cellular_component | membrane |
| E | 0004866 | molecular_function | endopeptidase inhibitor activity |
| F | 0004866 | molecular_function | endopeptidase inhibitor activity |
| F | 0005576 | cellular_component | extracellular region |
| F | 0005615 | cellular_component | extracellular space |
| H | 0016020 | cellular_component | membrane |
| I | 0004252 | molecular_function | serine-type endopeptidase activity |
| I | 0006508 | biological_process | proteolysis |
| J | 0004252 | molecular_function | serine-type endopeptidase activity |
| J | 0006508 | biological_process | proteolysis |
Functional Information from PROSITE/UniProt
| site_id | PS00477 |
| Number of Residues | 9 |
| Details | ALPHA_2_MACROGLOBULIN Alpha-2-macroglobulin family thiolester region signature. PsGCGEQnM |
| Chain | Residue | Details |
| B | PRO1007-MET1015 |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| I | LEU376-CYS381 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAckGDSGGPLV |
| Chain | Residue | Details |
| I | ASP519-VAL530 |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIpsqyq.CNgevDCitg.EDEvg...C |
| Chain | Residue | Details |
| D | CYS271-CYS293 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:P00750 |
| Chain | Residue | Details |
| I | HIS380 | |
| D | ASP283 | |
| D | ASP289 | |
| D | GLU290 | |
| H | LYS239 | |
| H | ASP242 | |
| H | ILE244 | |
| H | ASP246 | |
| H | ASP252 | |
| H | GLU253 | |
| H | TYR276 | |
| I | ASP429 | |
| H | ASN279 | |
| H | GLU281 | |
| H | ASP283 | |
| H | ASP289 | |
| H | GLU290 | |
| I | SER525 | |
| J | HIS380 | |
| J | ASP429 | |
| J | SER525 | |
| D | TYR276 | |
| D | ASN279 | |
| D | GLU281 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:21768352, ECO:0007744|PDB:2XRC |
| Chain | Residue | Details |
| I | ASN464 | |
| J | ASN464 | |
| H | ASN70 | |
| H | ASN177 | |
| E | SER38 | |
| E | SER70 | |
| E | SER297 | |
| E | SER303 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21768352, ECO:0007744|PDB:2XRC |
| Chain | Residue | Details |
| I | ASN494 | |
| J | ASN494 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:21768352, ECO:0007744|PDB:2XRC |
| Chain | Residue | Details |
| I | ASN536 | |
| J | ASN536 | |
| B | SER1573 | |
| F | SER968 | |
| F | SER1321 | |
| F | SER1573 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:17051150 |
| Chain | Residue | Details |
| B | ASN939 | |
| F | ASN939 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952 |
| Chain | Residue | Details |
| B | ASN1617 | |
| F | ASN1617 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CROSSLNK: Isoglutamyl cysteine thioester (Cys-Gln) |
| Chain | Residue | Details |
| B | CYS1010 | |
| B | GLN1013 | |
| F | CYS1010 | |
| F | GLN1013 |
