Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ADP A 401 |
| Chain | Residue |
| A | GLY48 |
| A | MET163 |
| A | ILE174 |
| A | ASP175 |
| A | MG402 |
| A | MG403 |
| A | HOH504 |
| A | HOH507 |
| A | SER51 |
| A | VAL53 |
| A | VAL66 |
| A | LYS68 |
| A | ILE95 |
| A | GLU114 |
| A | VAL116 |
| A | HIS160 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | ASN161 |
| A | ASP175 |
| A | ADP401 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | ASP175 |
| A | ADP401 |
| A | HOH507 |
| A | HOH510 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue IHP A 404 |
| Chain | Residue |
| A | HIS234 |
| A | HIS236 |
| A | ARG244 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 405 |
| Chain | Residue |
| A | ARG80 |
| A | ARG155 |
| A | HOH536 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 406 |
| Chain | Residue |
| A | HIS276 |
| A | SER277 |
| A | LYS279 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 407 |
| Chain | Residue |
| A | ARG191 |
| A | ALA193 |
| A | LYS198 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 408 |
| Chain | Residue |
| A | LYS158 |
| A | HIS160 |
| A | HOH504 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue OQC A 409 |
| Chain | Residue |
| A | TRP24 |
| A | VAL42 |
| A | HIS183 |
| A | GLN186 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue OQC A 410 |
| Chain | Residue |
| A | ILE140 |
| A | PRO159 |
| A | VAL162 |
| A | ILE164 |
| A | MET221 |
| A | MET225 |
| A | HOH551 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue OQC A 411 |
| Chain | Residue |
| A | GLN36 |
| A | TYR39 |
| A | ASP103 |
| A | THR108 |
| A | ALA110 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 412 |
| Chain | Residue |
| A | ARG195 |
| A | TYR196 |
| A | HIS234 |
| A | GLY235 |
| A | HIS236 |
| A | HOH505 |
| site_id | AD4 |
| Number of Residues | 15 |
| Details | binding site for residue ADP B 401 |
| Chain | Residue |
| B | GLY48 |
| B | LYS49 |
| B | SER51 |
| B | VAL53 |
| B | VAL66 |
| B | LYS68 |
| B | ILE95 |
| B | GLU114 |
| B | VAL116 |
| B | HIS160 |
| B | MET163 |
| B | ILE174 |
| B | ASP175 |
| B | MG402 |
| B | MG403 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 402 |
| Chain | Residue |
| B | PHE113 |
| B | ASP175 |
| B | ADP401 |
| B | HOH508 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 403 |
| Chain | Residue |
| B | ASN161 |
| B | ASP175 |
| B | ADP401 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue IHP B 404 |
| Chain | Residue |
| B | HIS234 |
| B | HIS236 |
| B | HIS236 |
| B | ARG244 |
| B | ARG244 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 405 |
| Chain | Residue |
| B | ARG195 |
| B | TYR196 |
| B | HIS234 |
| B | ARG244 |
| B | LYS247 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 406 |
| Chain | Residue |
| B | ARG80 |
| B | ARG155 |
| B | VAL192 |
| B | ACT407 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 407 |
| Chain | Residue |
| B | TYR188 |
| B | ASN189 |
| B | ACT406 |
| B | ARG155 |
| B | GLU180 |
| B | GLN186 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue OQC B 408 |
| Chain | Residue |
| B | GLN36 |
| B | TYR39 |
| B | GLN40 |
| B | LEU41 |
| B | ASP103 |
| B | THR108 |
| B | ALA110 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue OQC B 409 |
| Chain | Residue |
| B | TYR125 |
| B | ILE140 |
| B | PRO159 |
| B | VAL162 |
| B | MET221 |
| B | MET225 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnek..........VVVK |
| Chain | Residue | Details |
| A | LEU45-LYS68 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| B | ASP156 | |
| A | ASP156 | |
| Chain | Residue | Details |
| B | LEU45 | |
| B | LYS68 | |
| A | LEU45 | |
| A | LYS68 | |
