5LGB
Crystal structure of murine N1-acetylpolyamine oxidase in complex with MDL72527
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 41 |
| Details | binding site for residue 6YU A 601 |
| Chain | Residue |
| A | VAL11 |
| A | GLY44 |
| A | ARG45 |
| A | GLY59 |
| A | ALA60 |
| A | HIS61 |
| A | TRP62 |
| A | HIS64 |
| A | ASP211 |
| A | PRO239 |
| A | VAL240 |
| A | GLY12 |
| A | THR279 |
| A | VAL280 |
| A | PRO281 |
| A | PHE284 |
| A | ASN313 |
| A | TRP420 |
| A | TYR425 |
| A | TYR430 |
| A | GLY464 |
| A | GLU465 |
| A | GLY14 |
| A | SER473 |
| A | THR474 |
| A | THR475 |
| A | ALA478 |
| A | MD2602 |
| A | HOH719 |
| A | HOH724 |
| A | HOH727 |
| A | HOH737 |
| A | HOH750 |
| A | ILE15 |
| A | HOH774 |
| A | HOH782 |
| A | ALA16 |
| A | LEU36 |
| A | GLU37 |
| A | ALA38 |
| A | GLY43 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MD2 A 602 |
| Chain | Residue |
| A | GLU131 |
| A | VAL187 |
| A | PHE201 |
| A | TYR204 |
| A | TYR430 |
| A | SER473 |
| A | 6YU601 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28029774, ECO:0007744|PDB:5LAE, ECO:0007744|PDB:5LFO, ECO:0007744|PDB:5MBX |
| Chain | Residue | Details |
| A | ARG45 | |
| A | HIS61 | |
| A | VAL240 | |
| A | GLU465 | |
| A | THR474 | |
| A | ALA16 | |
| A | GLU37 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28029774, ECO:0007744|PDB:5MBX |
| Chain | Residue | Details |
| A | HIS64 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28029774, ECO:0007744|PDB:5LFO, ECO:0007744|PDB:5MBX |
| Chain | Residue | Details |
| A | VAL187 | |
| A | ASN313 |
