Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| A | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019166 | molecular_function | trans-2-enoyl-CoA reductase (NADPH) activity |
| B | 0141148 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | LYS204 |
| A | ALA353 |
| A | HOH515 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | ARG251 |
| A | ARG285 |
| A | SER309 |
| A | NA412 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | HOH501 |
| A | HOH544 |
| A | LYS278 |
| A | ARG285 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | GLN151 |
| A | HOH512 |
| A | HOH546 |
| A | HOH620 |
| B | LYS61 |
| B | HOH557 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue NAP A 405 |
| Chain | Residue |
| A | VAL171 |
| A | ASN172 |
| A | THR199 |
| A | SER200 |
| A | ALA201 |
| A | VAL202 |
| A | ARG222 |
| A | ARG224 |
| A | TYR296 |
| A | MET299 |
| A | PHE321 |
| A | TRP322 |
| A | VAL323 |
| A | LYS381 |
| A | SO4406 |
| A | HOH573 |
| A | HOH621 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | GLY197 |
| A | GLY198 |
| A | THR199 |
| A | ILE221 |
| A | ARG222 |
| A | ARG224 |
| A | NAP405 |
| A | HOH526 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | ASN100 |
| A | PRO124 |
| A | HIS126 |
| A | VAL127 |
| A | SER170 |
| A | LYS334 |
| A | GOL414 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| A | HIS126 |
| A | VAL127 |
| A | LYS331 |
| A | GOL414 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 409 |
| Chain | Residue |
| A | ASN248 |
| A | SER250 |
| A | ARG251 |
| A | ARG285 |
| A | LYS286 |
| A | HOH510 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 410 |
| Chain | Residue |
| A | ASN288 |
| A | ASN289 |
| A | LYS314 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 411 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 412 |
| Chain | Residue |
| A | THR308 |
| A | SER309 |
| A | SO4402 |
| A | HOH631 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 413 |
| Chain | Residue |
| A | TYR311 |
| A | ILE312 |
| A | ASN315 |
| A | HOH536 |
| A | HOH558 |
| B | GLY320 |
| B | TRP322 |
| B | GLU325 |
| B | HOH521 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 414 |
| Chain | Residue |
| A | VAL127 |
| A | SER170 |
| A | THR324 |
| A | LYS334 |
| A | SO4407 |
| A | SO4408 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 401 |
| Chain | Residue |
| A | GLY320 |
| A | PHE321 |
| A | TRP322 |
| A | HOH511 |
| B | TYR311 |
| B | ILE312 |
| B | ASN315 |
| B | HOH512 |
| B | HOH571 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | THR91 |
| B | THR92 |
| B | GLU93 |
| site_id | AD8 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | ARG222 |
| B | ARG224 |
| B | HOH510 |
| B | HOH641 |
| B | HOH672 |
| B | HOH695 |
| B | GLY197 |
| B | GLY198 |
| B | THR199 |
| B | ILE221 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| B | GLN33 |
| B | HIS34 |
| B | HOH559 |
| B | HOH637 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 405 |
| Chain | Residue |
| B | ARG285 |
| B | SER309 |
| B | NA408 |
| site_id | AE2 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 406 |
| Chain | Residue |
| B | PRO69 |
| B | ASN172 |
| B | ALA201 |
| B | LYS381 |
| B | NA407 |
| B | HOH611 |
| B | HOH614 |
| B | HOH678 |
| B | HOH700 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue NA B 407 |
| Chain | Residue |
| B | ALA201 |
| B | SO4406 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 408 |
| Chain | Residue |
| B | THR308 |
| B | SER309 |
| B | SO4405 |
| B | HOH662 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 409 |
| Chain | Residue |
| B | HIS182 |
| B | HOH521 |
| B | HOH570 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | TYR79 | |
| B | TYR79 | |
| Chain | Residue | Details |
| A | ARG222 | |
| A | TYR296 | |
| A | PHE321 | |
| A | LYS381 | |
| B | ASN172 | |
| B | THR199 | |
| B | ARG222 | |
| B | TYR296 | |
| B | PHE321 | |
| B | LYS381 | |
| A | ASN172 | |
| A | THR199 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| A | TYR79 | electrostatic stabiliser, increase electrophilicity |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 620 |
| Chain | Residue | Details |
| B | TYR79 | electrostatic stabiliser, increase electrophilicity |
