5IHL
STRUCTURE OF THE EXTRACELLULAR DOMAIN OF THE CD40 IN COMPLEX WITH 3H56-5 DAB
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0042113 | biological_process | B cell activation |
| A | 0050776 | biological_process | regulation of immune response |
| D | 0009897 | cellular_component | external side of plasma membrane |
| D | 0038023 | molecular_function | signaling receptor activity |
| D | 0042113 | biological_process | B cell activation |
| D | 0050776 | biological_process | regulation of immune response |
| F | 0009897 | cellular_component | external side of plasma membrane |
| F | 0038023 | molecular_function | signaling receptor activity |
| F | 0042113 | biological_process | B cell activation |
| F | 0050776 | biological_process | regulation of immune response |
| H | 0009897 | cellular_component | external side of plasma membrane |
| H | 0038023 | molecular_function | signaling receptor activity |
| H | 0042113 | biological_process | B cell activation |
| H | 0050776 | biological_process | regulation of immune response |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLU159 |
| A | LYS160 |
| A | HIS162 |
| B | ARG56 |
| I | SER82 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | GLU159 |
| B | ASN52 |
| B | GLN53 |
| B | ARG56 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | PRO96 |
| B | THR98 |
| B | ASP102 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 G 201 |
| Chain | Residue |
| G | LYS94 |
| G | PRO96 |
| G | THR98 |
| G | ASP101 |
| G | ASP102 |
Functional Information from PROSITE/UniProt
| site_id | PS00652 |
| Number of Residues | 34 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Crekq..Ylinsq.....C..Csl.Cqpgqklvsd..Cteft..ETEC |
| Chain | Residue | Details |
| A | CYS26-CYS59 |
| site_id | PS01186 |
| Number of Residues | 14 |
| Details | EGF_2 EGF-like domain signature 2. CtCeeGWhctsea..C |
| Chain | Residue | Details |
| A | CYS103-CYS116 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP153 | |
| A | ASP180 | |
| D | ASP153 | |
| D | ASP180 | |
| F | ASP153 | |
| F | ASP180 | |
| H | ASP153 | |
| H | ASP180 |
