5HWR

MvaS in complex with coenzyme A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004421	molecular_function	hydroxymethylglutaryl-CoA synthase activity
A	0006084	biological_process	acetyl-CoA metabolic process
A	0006696	biological_process	ergosterol biosynthetic process
A	0010142	biological_process	farnesyl diphosphate biosynthetic process, mevalonate pathway
A	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue GOL A 501

Chain	Residue
A	THR84
A	GLY85
A	HIS88
A	ARG194
A	HOH727

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site_id	AC2
Number of Residues	8
Details	binding site for residue GOL A 502

Chain	Residue
A	HOH623
A	HOH623
A	HOH826
A	HOH871
A	LYS101
A	LYS101
A	LEU102
A	LEU102

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site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 503

Chain	Residue
A	ARG246
A	GLN333
A	HOH618
A	HOH841
A	HOH853

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site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 504

Chain	Residue
A	GLN324
A	ASP365
A	LEU366
A	GLU367
A	HOH666
A	HOH722
A	HOH789

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site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 A 505

Chain	Residue
A	THR153
A	ALA154
A	HOH625
A	HOH860

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site_id	AC6
Number of Residues	1
Details	binding site for residue SO4 A 506

Chain	Residue
A	ARG42

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site_id	AC7
Number of Residues	30
Details	binding site for residue COA A 507

Chain	Residue
A	ASP31
A	ASP31
A	ALA33
A	LYS34
A	GLY38
A	TYR149
A	ALA154
A	GLY155
A	THR158
A	GLY205
A	HIS206
A	SER208
A	ILE209
A	TYR212
A	PRO252
A	PHE253
A	MET256
A	LYS259
A	HOH610
A	HOH627
A	HOH680
A	HOH695
A	HOH710
A	HOH714
A	HOH752
A	HOH800
A	HOH803
A	HOH833
A	HOH842
A	HOH870

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