5GZ5
Crystal structure of snake venom phosphodiesterase (PDE) from Taiwan cobra (Naja atra atra) in complex with AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0009143 | biological_process | nucleoside triphosphate catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0043262 | molecular_function | ADP phosphatase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
| A | 0090729 | molecular_function | toxin activity |
Functional Information from PROSITE/UniProt
| site_id | PS00524 |
| Number of Residues | 21 |
| Details | SMB_1 Somatomedin B domain (SMB) signature. CsCdnkCterka.CCwDYqdiC |
| Chain | Residue | Details |
| A | CYS49-CYS69 | |
| A | CYS93-CYS113 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: AMP-threonine intermediate => ECO:0000269|Ref.1, ECO:0007744|PDB:5GZ5 |
| Chain | Residue | Details |
| A | THR185 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|Ref.1, ECO:0007744|PDB:5GZ4, ECO:0007744|PDB:5GZ5 |
| Chain | Residue | Details |
| A | ASP352 | |
| A | HIS353 | |
| A | HIS462 | |
| A | ASP147 | |
| A | THR185 | |
| A | ASP305 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|Ref.1, ECO:0007744|PDB:5GZ5 |
| Chain | Residue | Details |
| A | HIS309 | |
| A | LYS271 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.1, ECO:0007744|PDB:5GZ4 |
| Chain | Residue | Details |
| A | ASN39 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.1, ECO:0007744|PDB:5GZ4, ECO:0007744|PDB:5GZ5 |
| Chain | Residue | Details |
| A | ASN259 | |
| A | ASN270 | |
| A | ASN512 | |
| A | ASN746 | |
| A | ASN216 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.1, ECO:0007744|PDB:5GZ5 |
| Chain | Residue | Details |
| A | ASN765 |
