Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004407 | molecular_function | histone deacetylase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0040029 | biological_process | epigenetic regulation of gene expression |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004407 | molecular_function | histone deacetylase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0040029 | biological_process | epigenetic regulation of gene expression |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1372 |
| Chain | Residue |
| A | ASP181 |
| A | HIS183 |
| A | ASP269 |
| A | 6DK1375 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 1373 |
| Chain | Residue |
| A | ASP179 |
| A | ASP181 |
| A | HIS183 |
| A | SER202 |
| A | LEU203 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1374 |
| Chain | Residue |
| A | TYR192 |
| A | ARG195 |
| A | VAL198 |
| A | PHE227 |
| A | HOH2188 |
| A | HOH2193 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 6DK A 1375 |
| Chain | Residue |
| A | THR24 |
| A | ASP101 |
| A | PRO141 |
| A | HIS143 |
| A | HIS144 |
| A | GLY152 |
| A | CYS154 |
| A | ASP181 |
| A | HIS183 |
| A | ASP269 |
| A | GLU310 |
| A | GLY311 |
| A | TYR313 |
| A | ZN1372 |
| B | LEU340 |
| B | PHE343 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1378 |
| Chain | Residue |
| B | ASP181 |
| B | HIS183 |
| B | ASP269 |
| B | 6DK1381 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 1379 |
| Chain | Residue |
| B | TYR192 |
| B | ARG195 |
| B | VAL198 |
| B | PHE227 |
| B | HOH2164 |
| B | HOH2169 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 1380 |
| Chain | Residue |
| B | ASP179 |
| B | ASP181 |
| B | HIS183 |
| B | SER202 |
| B | LEU203 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 6DK B 1381 |
| Chain | Residue |
| A | PHE343 |
| B | THR24 |
| B | LEU25 |
| B | ASP101 |
| B | PRO141 |
| B | HIS143 |
| B | HIS144 |
| B | GLY152 |
| B | CYS154 |
| B | ASP181 |
| B | HIS183 |
| B | PHE209 |
| B | ASP269 |
| B | GLU310 |
| B | GLY311 |
| B | TYR313 |
| B | ZN1378 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS144 | |
| B | HIS144 | |
| Chain | Residue | Details |
| A | ASP181 | |
| A | HIS183 | |
| A | ASP269 | |
| B | ASP181 | |
| B | HIS183 | |
| B | ASP269 | |
| Chain | Residue | Details |
| A | TYR313 | |
| B | TYR313 | |
