5FT8
Crystal structure of the complex between the cysteine desulfurase CsdA and the sulfur-acceptor CsdE in the persulfurated state at 2.50 Angstroem resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000096 | biological_process | sulfur amino acid metabolic process |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006534 | biological_process | cysteine metabolic process |
| A | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| A | 0009000 | molecular_function | selenocysteine lyase activity |
| A | 0016226 | biological_process | iron-sulfur cluster assembly |
| A | 0016261 | biological_process | selenocysteine catabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016783 | molecular_function | sulfurtransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019448 | biological_process | L-cysteine catabolic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0031071 | molecular_function | cysteine desulfurase activity |
| A | 0072348 | biological_process | sulfur compound transport |
| A | 1990221 | cellular_component | L-cysteine desulfurase complex |
| C | 0000096 | biological_process | sulfur amino acid metabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006534 | biological_process | cysteine metabolic process |
| C | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| C | 0009000 | molecular_function | selenocysteine lyase activity |
| C | 0016226 | biological_process | iron-sulfur cluster assembly |
| C | 0016261 | biological_process | selenocysteine catabolic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016783 | molecular_function | sulfurtransferase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019448 | biological_process | L-cysteine catabolic process |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0031071 | molecular_function | cysteine desulfurase activity |
| C | 0072348 | biological_process | sulfur compound transport |
| C | 1990221 | cellular_component | L-cysteine desulfurase complex |
| E | 0000096 | biological_process | sulfur amino acid metabolic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0006534 | biological_process | cysteine metabolic process |
| E | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| E | 0009000 | molecular_function | selenocysteine lyase activity |
| E | 0016226 | biological_process | iron-sulfur cluster assembly |
| E | 0016261 | biological_process | selenocysteine catabolic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016783 | molecular_function | sulfurtransferase activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016829 | molecular_function | lyase activity |
| E | 0019448 | biological_process | L-cysteine catabolic process |
| E | 0030170 | molecular_function | pyridoxal phosphate binding |
| E | 0031071 | molecular_function | cysteine desulfurase activity |
| E | 0072348 | biological_process | sulfur compound transport |
| E | 1990221 | cellular_component | L-cysteine desulfurase complex |
| G | 0000096 | biological_process | sulfur amino acid metabolic process |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0006534 | biological_process | cysteine metabolic process |
| G | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| G | 0009000 | molecular_function | selenocysteine lyase activity |
| G | 0016226 | biological_process | iron-sulfur cluster assembly |
| G | 0016261 | biological_process | selenocysteine catabolic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016783 | molecular_function | sulfurtransferase activity |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016829 | molecular_function | lyase activity |
| G | 0019448 | biological_process | L-cysteine catabolic process |
| G | 0030170 | molecular_function | pyridoxal phosphate binding |
| G | 0031071 | molecular_function | cysteine desulfurase activity |
| G | 0072348 | biological_process | sulfur compound transport |
| G | 1990221 | cellular_component | L-cysteine desulfurase complex |
| I | 0000096 | biological_process | sulfur amino acid metabolic process |
| I | 0003824 | molecular_function | catalytic activity |
| I | 0005515 | molecular_function | protein binding |
| I | 0006534 | biological_process | cysteine metabolic process |
| I | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| I | 0009000 | molecular_function | selenocysteine lyase activity |
| I | 0016226 | biological_process | iron-sulfur cluster assembly |
| I | 0016261 | biological_process | selenocysteine catabolic process |
| I | 0016740 | molecular_function | transferase activity |
| I | 0016783 | molecular_function | sulfurtransferase activity |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0016829 | molecular_function | lyase activity |
| I | 0019448 | biological_process | L-cysteine catabolic process |
| I | 0030170 | molecular_function | pyridoxal phosphate binding |
| I | 0031071 | molecular_function | cysteine desulfurase activity |
| I | 0072348 | biological_process | sulfur compound transport |
| I | 1990221 | cellular_component | L-cysteine desulfurase complex |
| K | 0000096 | biological_process | sulfur amino acid metabolic process |
| K | 0003824 | molecular_function | catalytic activity |
| K | 0005515 | molecular_function | protein binding |
| K | 0006534 | biological_process | cysteine metabolic process |
| K | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| K | 0009000 | molecular_function | selenocysteine lyase activity |
| K | 0016226 | biological_process | iron-sulfur cluster assembly |
| K | 0016261 | biological_process | selenocysteine catabolic process |
| K | 0016740 | molecular_function | transferase activity |
| K | 0016783 | molecular_function | sulfurtransferase activity |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0016829 | molecular_function | lyase activity |
| K | 0019448 | biological_process | L-cysteine catabolic process |
| K | 0030170 | molecular_function | pyridoxal phosphate binding |
| K | 0031071 | molecular_function | cysteine desulfurase activity |
| K | 0072348 | biological_process | sulfur compound transport |
| K | 1990221 | cellular_component | L-cysteine desulfurase complex |
| M | 0000096 | biological_process | sulfur amino acid metabolic process |
| M | 0003824 | molecular_function | catalytic activity |
| M | 0005515 | molecular_function | protein binding |
| M | 0006534 | biological_process | cysteine metabolic process |
| M | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| M | 0009000 | molecular_function | selenocysteine lyase activity |
| M | 0016226 | biological_process | iron-sulfur cluster assembly |
| M | 0016261 | biological_process | selenocysteine catabolic process |
| M | 0016740 | molecular_function | transferase activity |
| M | 0016783 | molecular_function | sulfurtransferase activity |
| M | 0016787 | molecular_function | hydrolase activity |
| M | 0016829 | molecular_function | lyase activity |
| M | 0019448 | biological_process | L-cysteine catabolic process |
| M | 0030170 | molecular_function | pyridoxal phosphate binding |
| M | 0031071 | molecular_function | cysteine desulfurase activity |
| M | 0072348 | biological_process | sulfur compound transport |
| M | 1990221 | cellular_component | L-cysteine desulfurase complex |
| O | 0000096 | biological_process | sulfur amino acid metabolic process |
| O | 0003824 | molecular_function | catalytic activity |
| O | 0005515 | molecular_function | protein binding |
| O | 0006534 | biological_process | cysteine metabolic process |
| O | 0008826 | molecular_function | cysteine sulfinate desulfinase activity |
| O | 0009000 | molecular_function | selenocysteine lyase activity |
| O | 0016226 | biological_process | iron-sulfur cluster assembly |
| O | 0016261 | biological_process | selenocysteine catabolic process |
| O | 0016740 | molecular_function | transferase activity |
| O | 0016783 | molecular_function | sulfurtransferase activity |
| O | 0016787 | molecular_function | hydrolase activity |
| O | 0016829 | molecular_function | lyase activity |
| O | 0019448 | biological_process | L-cysteine catabolic process |
| O | 0030170 | molecular_function | pyridoxal phosphate binding |
| O | 0031071 | molecular_function | cysteine desulfurase activity |
| O | 0072348 | biological_process | sulfur compound transport |
| O | 1990221 | cellular_component | L-cysteine desulfurase complex |
| Q | 0005515 | molecular_function | protein binding |
| Q | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| Q | 0097163 | molecular_function | sulfur carrier activity |
| S | 0005515 | molecular_function | protein binding |
| S | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| S | 0097163 | molecular_function | sulfur carrier activity |
| U | 0005515 | molecular_function | protein binding |
| U | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| U | 0097163 | molecular_function | sulfur carrier activity |
| W | 0005515 | molecular_function | protein binding |
| W | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| W | 0097163 | molecular_function | sulfur carrier activity |
| Y | 0005515 | molecular_function | protein binding |
| Y | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| Y | 0097163 | molecular_function | sulfur carrier activity |
| a | 0005515 | molecular_function | protein binding |
| a | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| a | 0097163 | molecular_function | sulfur carrier activity |
| c | 0005515 | molecular_function | protein binding |
| c | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| c | 0097163 | molecular_function | sulfur carrier activity |
| e | 0005515 | molecular_function | protein binding |
| e | 0061504 | biological_process | cyclic threonylcarbamoyladenosine biosynthetic process |
| e | 0097163 | molecular_function | sulfur carrier activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP A 501 |
| Chain | Residue |
| A | THR90 |
| A | LYS222 |
| A | HOH654 |
| A | HOH692 |
| C | THR273 |
| A | THR91 |
| A | HIS119 |
| A | ASN171 |
| A | ASP196 |
| A | ALA198 |
| A | GLN199 |
| A | SER219 |
| A | HIS221 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CSS A 358 |
| Chain | Residue |
| A | HIS119 |
| A | HIS120 |
| A | GLN356 |
| A | HIS357 |
| A | ALA359 |
| C | HOH703 |
| C | GLY249 |
| C | LYS250 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG A 502 |
| Chain | Residue |
| A | GLN99 |
| A | ARG103 |
| A | PRO244 |
| A | TRP245 |
| C | GLN99 |
| C | ARG103 |
| C | MET128 |
| C | GLN132 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 503 |
| Chain | Residue |
| A | ARG60 |
| A | ALA63 |
| A | ARG64 |
| A | ALA67 |
| A | LYS71 |
| A | GLU287 |
| A | HOH635 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 504 |
| Chain | Residue |
| A | GLN41 |
| A | SER44 |
| A | GLN54 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 505 |
| Chain | Residue |
| A | HIS187 |
| A | ASP212 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 506 |
| Chain | Residue |
| A | MET1 |
| A | VAL3 |
| A | GLN8 |
| A | ASP291 |
| A | TYR292 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 507 |
| Chain | Residue |
| A | GLU37 |
| A | GLN41 |
| A | GLU57 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 508 |
| Chain | Residue |
| A | LYS314 |
| A | ARG315 |
| A | HOH680 |
| A | HOH673 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 509 |
| Chain | Residue |
| A | ASN143 |
| A | GLN145 |
| A | ASP149 |
| A | ASP151 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 510 |
| Chain | Residue |
| A | PHE42 |
| A | THR62 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 511 |
| Chain | Residue |
| A | THR306 |
| A | GLU309 |
| A | ASP310 |
| A | ASP325 |
| A | GOL512 |
| A | HOH607 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 512 |
| Chain | Residue |
| A | GLU309 |
| A | ASP310 |
| A | ALA313 |
| A | GOL511 |
| A | HOH678 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 513 |
| Chain | Residue |
| A | ALA364 |
| A | GLU365 |
| A | LEU366 |
| A | GLY367 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 514 |
| Chain | Residue |
| A | GLN74 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL A 515 |
| Chain | Residue |
| A | ASP258 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CSS Q 61 |
| Chain | Residue |
| A | GLY355 |
| A | GLN356 |
| A | HOH618 |
| A | HOH723 |
| Q | GLY60 |
| Q | GLU62 |
| Q | ASN63 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG Q 201 |
| Chain | Residue |
| Q | SER126 |
| Q | ALA127 |
| Q | SER128 |
| Q | ARG129 |
| Q | SER130 |
| Q | GLN131 |
| G | GLU155 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL Q 202 |
| Chain | Residue |
| Q | SER111 |
| Q | HOH308 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL Q 203 |
| Chain | Residue |
| A | GLU347 |
| Q | TRP30 |
| Q | HOH326 |
| site_id | CC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP C 501 |
| Chain | Residue |
| C | HIS119 |
| C | ASN171 |
| C | ASP196 |
| C | ALA198 |
| C | GLN199 |
| C | SER219 |
| C | HIS221 |
| C | LYS222 |
| C | HOH623 |
| C | HOH641 |
| A | THR273 |
| A | HOH624 |
| C | THR90 |
| C | THR91 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CSS C 358 |
| Chain | Residue |
| A | GLY249 |
| C | HIS119 |
| C | HIS120 |
| C | GLN356 |
| C | HIS357 |
| C | ALA359 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG C 502 |
| Chain | Residue |
| C | THR261 |
| C | HOH622 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG C 503 |
| Chain | Residue |
| C | VAL137 |
| C | VAL138 |
| C | PEG504 |
| C | HOH636 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG C 504 |
| Chain | Residue |
| C | GLU111 |
| C | PEG503 |
| C | HOH636 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG C 505 |
| Chain | Residue |
| C | GLN74 |
| C | GOL509 |
| C | HOH654 |
| C | HOH639 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 506 |
| Chain | Residue |
| C | GLU240 |
| C | HOH604 |
| I | SER188 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 507 |
| Chain | Residue |
| C | THR62 |
| C | GOL508 |
| site_id | DC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL C 508 |
| Chain | Residue |
| C | GOL507 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 509 |
| Chain | Residue |
| C | GLU70 |
| C | GLN74 |
| C | ASN77 |
| C | ALA78 |
| C | PRO79 |
| C | PEG505 |
| C | HOH654 |
| site_id | DC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL C 510 |
| Chain | Residue |
| C | PRO316 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 511 |
| Chain | Residue |
| C | ALA364 |
| C | GLY367 |
| site_id | DC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 512 |
| Chain | Residue |
| C | PRO108 |
| I | GLN107 |
| I | PRO108 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 513 |
| Chain | Residue |
| C | GLY367 |
| C | THR369 |
| C | HOH617 |
| C | HOH640 |
| site_id | DC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 514 |
| Chain | Residue |
| C | GLU309 |
| C | ASP310 |
| C | ASP325 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 515 |
| Chain | Residue |
| C | TYR65 |
| C | ARG69 |
| C | TRP86 |
| site_id | EC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 516 |
| Chain | Residue |
| A | VAL137 |
| C | ASP258 |
| U | GLU18 |
| U | ARG21 |
| site_id | EC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CSS S 61 |
| Chain | Residue |
| C | ALA354 |
| S | GLY60 |
| S | GLU62 |
| S | ASN63 |
| site_id | EC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL S 201 |
| Chain | Residue |
| S | LEU27 |
| S | LYS33 |
| S | GLU118 |
| S | LEU119 |
| S | GLY120 |
| E | LYS136 |
| site_id | EC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PLP E 501 |
| Chain | Residue |
| E | THR90 |
| E | THR91 |
| E | HIS119 |
| E | ASN171 |
| E | ASP196 |
| E | ALA198 |
| E | GLN199 |
| E | SER219 |
| E | HIS221 |
| E | LYS222 |
| E | HOH673 |
| E | HOH605 |
| G | HOH606 |
| G | THR273 |
| site_id | EC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CSS E 358 |
| Chain | Residue |
| E | HIS119 |
| E | HIS120 |
| E | GLN356 |
| E | HIS357 |
| E | ALA359 |
| G | GLY249 |
| G | LYS250 |
| site_id | EC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG E 502 |
| Chain | Residue |
| E | ARG302 |
| site_id | EC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG E 503 |
| Chain | Residue |
| E | ASP212 |
| E | GOL515 |
| E | HOH680 |
| site_id | EC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG E 504 |
| Chain | Residue |
| E | GLN132 |
| site_id | EC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG E 505 |
| Chain | Residue |
| E | ARG103 |
| E | GLN132 |
| E | HOH604 |
| E | HOH639 |
| G | ARG103 |
| site_id | FC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL E 506 |
| Chain | Residue |
| E | THR262 |
| E | GLN263 |
| site_id | FC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL E 507 |
| Chain | Residue |
| E | GLU237 |
| E | ALA241 |
| site_id | FC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL E 508 |
| Chain | Residue |
| E | GLU66 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 509 |
| Chain | Residue |
| A | GLN59 |
| E | PRO104 |
| E | ARG105 |
| E | GLN107 |
| site_id | FC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL E 510 |
| Chain | Residue |
| E | ARG10 |
| E | LEU16 |
| E | GLN17 |
| site_id | FC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL E 511 |
| Chain | Residue |
| E | HOH666 |
| I | ASP149 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL E 512 |
| Chain | Residue |
| E | CYS176 |
| E | PRO177 |
| E | ASP178 |
| E | GLN324 |
| E | HOH638 |
| site_id | FC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL E 513 |
| Chain | Residue |
| E | ASP80 |
| E | LYS82 |
| site_id | FC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL E 514 |
| Chain | Residue |
| E | ASN77 |
| site_id | GC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL E 515 |
| Chain | Residue |
| E | PEG503 |
| site_id | GC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CSS U 61 |
| Chain | Residue |
| E | GLY355 |
| E | HIS357 |
| E | HOH671 |
| U | GLY60 |
| U | GLU62 |
| U | ASN63 |
| site_id | GC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP G 501 |
| Chain | Residue |
| E | THR273 |
| G | HOH646 |
| G | HOH671 |
| G | THR90 |
| G | THR91 |
| G | HIS119 |
| G | ASN171 |
| G | ASP196 |
| G | ALA198 |
| G | GLN199 |
| G | SER219 |
| G | HIS221 |
| G | LYS222 |
| site_id | GC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CSS G 358 |
| Chain | Residue |
| E | GLY249 |
| E | HOH662 |
| G | HIS119 |
| G | HIS120 |
| G | GLN356 |
| G | HIS357 |
| G | ALA359 |
| site_id | GC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG G 502 |
| Chain | Residue |
| E | GLN131 |
| G | ASP258 |
| site_id | GC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL G 503 |
| Chain | Residue |
| E | ASN49 |
| G | HOH607 |
| G | ASP24 |
| G | VAL342 |
| G | LEU352 |
| G | ARG353 |
| G | HOH603 |
| site_id | GC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL G 504 |
| Chain | Residue |
| G | SER303 |
| G | THR306 |
| G | LEU307 |
| site_id | GC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL G 505 |
| Chain | Residue |
| G | MET1 |
| site_id | GC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL G 506 |
| Chain | Residue |
| G | HIS51 |
| G | PHE55 |
| site_id | HC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL G 507 |
| Chain | Residue |
| G | PRO79 |
| G | ASP80 |
| site_id | HC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL G 508 |
| Chain | Residue |
| G | ALA313 |
| G | ARG315 |
| G | PRO316 |
| G | GLY317 |
| G | PHE318 |
| G | HOH658 |
| site_id | HC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL G 509 |
| Chain | Residue |
| G | GLN40 |
| site_id | HC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CSS W 61 |
| Chain | Residue |
| G | GLN356 |
| W | GLY60 |
| W | GLU62 |
| W | ASN63 |
| site_id | HC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG W 201 |
| Chain | Residue |
| W | PRO48 |
| W | ASP49 |
| site_id | HC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL W 202 |
| Chain | Residue |
| A | GLN17 |
| C | ARG52 |
| C | SER53 |
| W | GLN146 |
| W | LYS148 |
| site_id | HC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP I 501 |
| Chain | Residue |
| I | THR90 |
| I | THR91 |
| I | HIS119 |
| I | ASN171 |
| I | ASP196 |
| I | ALA198 |
| I | GLN199 |
| I | SER219 |
| I | HIS221 |
| I | LYS222 |
| I | HOH655 |
| I | HOH652 |
| K | THR273 |
| site_id | HC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CSS I 358 |
| Chain | Residue |
| I | HIS119 |
| I | HIS120 |
| I | GLN356 |
| I | HIS357 |
| I | ALA359 |
| Y | CSS61 |
| K | GLY249 |
| K | LYS250 |
| site_id | HC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG I 502 |
| Chain | Residue |
| I | PRO108 |
| I | GLY134 |
| I | LYS136 |
| I | HOH606 |
| I | HOH605 |
| site_id | IC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL I 503 |
| Chain | Residue |
| I | ASN2 |
| I | VAL3 |
| I | PHE4 |
| I | ASN5 |
| I | ASP293 |
| site_id | IC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL I 504 |
| Chain | Residue |
| I | GLU33 |
| site_id | IC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL I 505 |
| Chain | Residue |
| I | ASP386 |
| I | ALA387 |
| I | ASN390 |
| site_id | IC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL I 506 |
| Chain | Residue |
| C | HOH650 |
| I | LYS235 |
| I | GLU237 |
| site_id | IC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CSS Y 61 |
| Chain | Residue |
| I | GLY355 |
| I | GLN356 |
| I | HIS357 |
| I | CSS358 |
| I | HOH669 |
| Y | GLY60 |
| Y | GLU62 |
| Y | ASN63 |
| site_id | IC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP K 501 |
| Chain | Residue |
| I | THR273 |
| K | HOH617 |
| I | HOH610 |
| K | THR90 |
| K | THR91 |
| K | HIS119 |
| K | ASN171 |
| K | ASP196 |
| K | ALA198 |
| K | GLN199 |
| K | SER219 |
| K | HIS221 |
| K | LYS222 |
| site_id | IC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CSS K 358 |
| Chain | Residue |
| I | GLY249 |
| K | HIS119 |
| K | HIS120 |
| K | GLN356 |
| K | HIS357 |
| K | ALA359 |
| site_id | IC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG K 502 |
| Chain | Residue |
| K | GLN263 |
| K | TRP267 |
| site_id | IC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CSS a 61 |
| Chain | Residue |
| K | GLN356 |
| a | HOH202 |
| a | GLY60 |
| a | GLU62 |
| a | ASN63 |
| a | HOH205 |
| site_id | JC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP M 501 |
| Chain | Residue |
| M | THR90 |
| M | THR91 |
| M | HIS119 |
| M | ASN171 |
| M | ASP196 |
| M | ALA198 |
| M | GLN199 |
| M | SER219 |
| M | HIS221 |
| M | LYS222 |
| O | THR273 |
| site_id | JC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CSS M 358 |
| Chain | Residue |
| M | HIS119 |
| M | HIS120 |
| M | GLN356 |
| M | HIS357 |
| M | ALA359 |
| O | GLY249 |
| site_id | JC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL M 502 |
| Chain | Residue |
| K | LYS314 |
| M | ASP310 |
| site_id | JC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CSS c 61 |
| Chain | Residue |
| M | GLN356 |
| c | GLY60 |
| c | GLU62 |
| c | ASN63 |
| site_id | JC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PLP O 501 |
| Chain | Residue |
| M | THR273 |
| O | THR90 |
| O | THR91 |
| O | HIS119 |
| O | ASN171 |
| O | ASP196 |
| O | ALA198 |
| O | GLN199 |
| O | SER219 |
| O | HIS221 |
| O | LYS222 |
| site_id | JC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CSS O 358 |
| Chain | Residue |
| O | HIS119 |
| O | HIS120 |
| O | GLN356 |
| O | HIS357 |
| O | ALA359 |
Functional Information from PROSITE/UniProt
| site_id | PS00595 |
| Number of Residues | 20 |
| Details | AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. IDFYafSGHKlygpt.GiGvL |
| Chain | Residue | Details |
| A | ILE213-LEU232 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: Cysteine persulfide intermediate |
| Chain | Residue | Details |
| Q | CSS61 | |
| S | CSS61 | |
| U | CSS61 | |
| W | CSS61 | |
| Y | CSS61 | |
| a | CSS61 | |
| c | CSS61 | |
| e | CSS41 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | MOD_RES: Cysteine persulfide => ECO:0000269|PubMed:15901727 |
| Chain | Residue | Details |
| Q | CSS61 | |
| S | CSS61 | |
| U | CSS61 | |
| W | CSS61 | |
| Y | CSS61 | |
| a | CSS61 | |
| c | CSS61 | |
| e | CSS41 |
