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5DTW

Crystal structure of M. tuberculosis EchA6 bound to C20-CoA

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004300molecular_functionenoyl-CoA hydratase activity
A0005886cellular_componentplasma membrane
A0006631biological_processfatty acid metabolic process
A0006635biological_processfatty acid beta-oxidation
A0009274cellular_componentpeptidoglycan-based cell wall
A0016829molecular_functionlyase activity
A0016836molecular_functionhydro-lyase activity
B0003824molecular_functioncatalytic activity
B0004300molecular_functionenoyl-CoA hydratase activity
B0005886cellular_componentplasma membrane
B0006631biological_processfatty acid metabolic process
B0006635biological_processfatty acid beta-oxidation
B0009274cellular_componentpeptidoglycan-based cell wall
B0016829molecular_functionlyase activity
B0016836molecular_functionhydro-lyase activity
C0003824molecular_functioncatalytic activity
C0004300molecular_functionenoyl-CoA hydratase activity
C0005886cellular_componentplasma membrane
C0006631biological_processfatty acid metabolic process
C0006635biological_processfatty acid beta-oxidation
C0009274cellular_componentpeptidoglycan-based cell wall
C0016829molecular_functionlyase activity
C0016836molecular_functionhydro-lyase activity
D0003824molecular_functioncatalytic activity
D0004300molecular_functionenoyl-CoA hydratase activity
D0005886cellular_componentplasma membrane
D0006631biological_processfatty acid metabolic process
D0006635biological_processfatty acid beta-oxidation
D0009274cellular_componentpeptidoglycan-based cell wall
D0016829molecular_functionlyase activity
D0016836molecular_functionhydro-lyase activity
E0003824molecular_functioncatalytic activity
E0004300molecular_functionenoyl-CoA hydratase activity
E0005886cellular_componentplasma membrane
E0006631biological_processfatty acid metabolic process
E0006635biological_processfatty acid beta-oxidation
E0009274cellular_componentpeptidoglycan-based cell wall
E0016829molecular_functionlyase activity
E0016836molecular_functionhydro-lyase activity
F0003824molecular_functioncatalytic activity
F0004300molecular_functionenoyl-CoA hydratase activity
F0005886cellular_componentplasma membrane
F0006631biological_processfatty acid metabolic process
F0006635biological_processfatty acid beta-oxidation
F0009274cellular_componentpeptidoglycan-based cell wall
F0016829molecular_functionlyase activity
F0016836molecular_functionhydro-lyase activity
Functional Information from PDB Data
site_idAC1
Number of Residues21
Detailsbinding site for residue 5F9 A 301
ChainResidue
AGLU19
AILE76
AHIS79
AASP83
AGLY99
AALA100
ATYR126
ATRP133
AHOH401
DARG17
DARG20
AARG20
DSER63
DHOH402
AARG21
AALA23
AALA58
AGLY59
AALA60
AASP61
ALEU62

site_idAC2
Number of Residues20
Detailsbinding site for residue 5F9 D 301
ChainResidue
AARG17
AARG20
DGLU19
DARG20
DARG21
DALA23
DALA58
DALA60
DASP61
DLEU62
DLEU75
DHIS79
DASP83
DALA100
DGLN103
DGLN107
DTYR126
DLEU128
DASP131
DTRP133

Functional Information from PROSITE/UniProt
site_idPS00166
Number of Residues21
DetailsENOYL_COA_HYDRATASE Enoyl-CoA hydratase/isomerase signature. VGaINGpaiGAGlqlaMqCDL
ChainResidueDetails
AVAL90-LEU110

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PDB entries from 2024-05-29

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