5DA8

Crystal structure of chaperonin GroEL from

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006457	biological_process	protein folding
A	0009408	biological_process	response to heat
A	0016853	molecular_function	isomerase activity
A	0032727	biological_process	positive regulation of interferon-alpha production
A	0032729	biological_process	positive regulation of type II interferon production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0034514	biological_process	mitochondrial unfolded protein response
A	0042026	biological_process	protein refolding
A	0045041	biological_process	protein import into mitochondrial intermembrane space
A	0050870	biological_process	positive regulation of T cell activation
A	0051082	molecular_function	unfolded protein binding
A	0051085	biological_process	chaperone cofactor-dependent protein refolding
A	0051087	molecular_function	protein-folding chaperone binding
A	0140662	molecular_function	ATP-dependent protein folding chaperone
A	1990220	cellular_component	GroEL-GroES complex
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006457	biological_process	protein folding
B	0009408	biological_process	response to heat
B	0016853	molecular_function	isomerase activity
B	0032727	biological_process	positive regulation of interferon-alpha production
B	0032729	biological_process	positive regulation of type II interferon production
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0034514	biological_process	mitochondrial unfolded protein response
B	0042026	biological_process	protein refolding
B	0045041	biological_process	protein import into mitochondrial intermembrane space
B	0050870	biological_process	positive regulation of T cell activation
B	0051082	molecular_function	unfolded protein binding
B	0051085	biological_process	chaperone cofactor-dependent protein refolding
B	0051087	molecular_function	protein-folding chaperone binding
B	0140662	molecular_function	ATP-dependent protein folding chaperone
B	1990220	cellular_component	GroEL-GroES complex
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006457	biological_process	protein folding
C	0009408	biological_process	response to heat
C	0016853	molecular_function	isomerase activity
C	0032727	biological_process	positive regulation of interferon-alpha production
C	0032729	biological_process	positive regulation of type II interferon production
C	0032755	biological_process	positive regulation of interleukin-6 production
C	0034514	biological_process	mitochondrial unfolded protein response
C	0042026	biological_process	protein refolding
C	0045041	biological_process	protein import into mitochondrial intermembrane space
C	0050870	biological_process	positive regulation of T cell activation
C	0051082	molecular_function	unfolded protein binding
C	0051085	biological_process	chaperone cofactor-dependent protein refolding
C	0051087	molecular_function	protein-folding chaperone binding
C	0140662	molecular_function	ATP-dependent protein folding chaperone
C	1990220	cellular_component	GroEL-GroES complex
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006457	biological_process	protein folding
D	0009408	biological_process	response to heat
D	0016853	molecular_function	isomerase activity
D	0032727	biological_process	positive regulation of interferon-alpha production
D	0032729	biological_process	positive regulation of type II interferon production
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0034514	biological_process	mitochondrial unfolded protein response
D	0042026	biological_process	protein refolding
D	0045041	biological_process	protein import into mitochondrial intermembrane space
D	0050870	biological_process	positive regulation of T cell activation
D	0051082	molecular_function	unfolded protein binding
D	0051085	biological_process	chaperone cofactor-dependent protein refolding
D	0051087	molecular_function	protein-folding chaperone binding
D	0140662	molecular_function	ATP-dependent protein folding chaperone
D	1990220	cellular_component	GroEL-GroES complex
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006457	biological_process	protein folding
E	0009408	biological_process	response to heat
E	0016853	molecular_function	isomerase activity
E	0032727	biological_process	positive regulation of interferon-alpha production
E	0032729	biological_process	positive regulation of type II interferon production
E	0032755	biological_process	positive regulation of interleukin-6 production
E	0034514	biological_process	mitochondrial unfolded protein response
E	0042026	biological_process	protein refolding
E	0045041	biological_process	protein import into mitochondrial intermembrane space
E	0050870	biological_process	positive regulation of T cell activation
E	0051082	molecular_function	unfolded protein binding
E	0051085	biological_process	chaperone cofactor-dependent protein refolding
E	0051087	molecular_function	protein-folding chaperone binding
E	0140662	molecular_function	ATP-dependent protein folding chaperone
E	1990220	cellular_component	GroEL-GroES complex
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006457	biological_process	protein folding
F	0009408	biological_process	response to heat
F	0016853	molecular_function	isomerase activity
F	0032727	biological_process	positive regulation of interferon-alpha production
F	0032729	biological_process	positive regulation of type II interferon production
F	0032755	biological_process	positive regulation of interleukin-6 production
F	0034514	biological_process	mitochondrial unfolded protein response
F	0042026	biological_process	protein refolding
F	0045041	biological_process	protein import into mitochondrial intermembrane space
F	0050870	biological_process	positive regulation of T cell activation
F	0051082	molecular_function	unfolded protein binding
F	0051085	biological_process	chaperone cofactor-dependent protein refolding
F	0051087	molecular_function	protein-folding chaperone binding
F	0140662	molecular_function	ATP-dependent protein folding chaperone
F	1990220	cellular_component	GroEL-GroES complex
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006457	biological_process	protein folding
G	0009408	biological_process	response to heat
G	0016853	molecular_function	isomerase activity
G	0032727	biological_process	positive regulation of interferon-alpha production
G	0032729	biological_process	positive regulation of type II interferon production
G	0032755	biological_process	positive regulation of interleukin-6 production
G	0034514	biological_process	mitochondrial unfolded protein response
G	0042026	biological_process	protein refolding
G	0045041	biological_process	protein import into mitochondrial intermembrane space
G	0050870	biological_process	positive regulation of T cell activation
G	0051082	molecular_function	unfolded protein binding
G	0051085	biological_process	chaperone cofactor-dependent protein refolding
G	0051087	molecular_function	protein-folding chaperone binding
G	0140662	molecular_function	ATP-dependent protein folding chaperone
G	1990220	cellular_component	GroEL-GroES complex
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006457	biological_process	protein folding
H	0009408	biological_process	response to heat
H	0016853	molecular_function	isomerase activity
H	0032727	biological_process	positive regulation of interferon-alpha production
H	0032729	biological_process	positive regulation of type II interferon production
H	0032755	biological_process	positive regulation of interleukin-6 production
H	0034514	biological_process	mitochondrial unfolded protein response
H	0042026	biological_process	protein refolding
H	0045041	biological_process	protein import into mitochondrial intermembrane space
H	0050870	biological_process	positive regulation of T cell activation
H	0051082	molecular_function	unfolded protein binding
H	0051085	biological_process	chaperone cofactor-dependent protein refolding
H	0051087	molecular_function	protein-folding chaperone binding
H	0140662	molecular_function	ATP-dependent protein folding chaperone
H	1990220	cellular_component	GroEL-GroES complex
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006457	biological_process	protein folding
I	0009408	biological_process	response to heat
I	0016853	molecular_function	isomerase activity
I	0032727	biological_process	positive regulation of interferon-alpha production
I	0032729	biological_process	positive regulation of type II interferon production
I	0032755	biological_process	positive regulation of interleukin-6 production
I	0034514	biological_process	mitochondrial unfolded protein response
I	0042026	biological_process	protein refolding
I	0045041	biological_process	protein import into mitochondrial intermembrane space
I	0050870	biological_process	positive regulation of T cell activation
I	0051082	molecular_function	unfolded protein binding
I	0051085	biological_process	chaperone cofactor-dependent protein refolding
I	0051087	molecular_function	protein-folding chaperone binding
I	0140662	molecular_function	ATP-dependent protein folding chaperone
I	1990220	cellular_component	GroEL-GroES complex
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006457	biological_process	protein folding
J	0009408	biological_process	response to heat
J	0016853	molecular_function	isomerase activity
J	0032727	biological_process	positive regulation of interferon-alpha production
J	0032729	biological_process	positive regulation of type II interferon production
J	0032755	biological_process	positive regulation of interleukin-6 production
J	0034514	biological_process	mitochondrial unfolded protein response
J	0042026	biological_process	protein refolding
J	0045041	biological_process	protein import into mitochondrial intermembrane space
J	0050870	biological_process	positive regulation of T cell activation
J	0051082	molecular_function	unfolded protein binding
J	0051085	biological_process	chaperone cofactor-dependent protein refolding
J	0051087	molecular_function	protein-folding chaperone binding
J	0140662	molecular_function	ATP-dependent protein folding chaperone
J	1990220	cellular_component	GroEL-GroES complex
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0006457	biological_process	protein folding
K	0009408	biological_process	response to heat
K	0016853	molecular_function	isomerase activity
K	0032727	biological_process	positive regulation of interferon-alpha production
K	0032729	biological_process	positive regulation of type II interferon production
K	0032755	biological_process	positive regulation of interleukin-6 production
K	0034514	biological_process	mitochondrial unfolded protein response
K	0042026	biological_process	protein refolding
K	0045041	biological_process	protein import into mitochondrial intermembrane space
K	0050870	biological_process	positive regulation of T cell activation
K	0051082	molecular_function	unfolded protein binding
K	0051085	biological_process	chaperone cofactor-dependent protein refolding
K	0051087	molecular_function	protein-folding chaperone binding
K	0140662	molecular_function	ATP-dependent protein folding chaperone
K	1990220	cellular_component	GroEL-GroES complex
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0006457	biological_process	protein folding
L	0009408	biological_process	response to heat
L	0016853	molecular_function	isomerase activity
L	0032727	biological_process	positive regulation of interferon-alpha production
L	0032729	biological_process	positive regulation of type II interferon production
L	0032755	biological_process	positive regulation of interleukin-6 production
L	0034514	biological_process	mitochondrial unfolded protein response
L	0042026	biological_process	protein refolding
L	0045041	biological_process	protein import into mitochondrial intermembrane space
L	0050870	biological_process	positive regulation of T cell activation
L	0051082	molecular_function	unfolded protein binding
L	0051085	biological_process	chaperone cofactor-dependent protein refolding
L	0051087	molecular_function	protein-folding chaperone binding
L	0140662	molecular_function	ATP-dependent protein folding chaperone
L	1990220	cellular_component	GroEL-GroES complex
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0006457	biological_process	protein folding
M	0009408	biological_process	response to heat
M	0016853	molecular_function	isomerase activity
M	0032727	biological_process	positive regulation of interferon-alpha production
M	0032729	biological_process	positive regulation of type II interferon production
M	0032755	biological_process	positive regulation of interleukin-6 production
M	0034514	biological_process	mitochondrial unfolded protein response
M	0042026	biological_process	protein refolding
M	0045041	biological_process	protein import into mitochondrial intermembrane space
M	0050870	biological_process	positive regulation of T cell activation
M	0051082	molecular_function	unfolded protein binding
M	0051085	biological_process	chaperone cofactor-dependent protein refolding
M	0051087	molecular_function	protein-folding chaperone binding
M	0140662	molecular_function	ATP-dependent protein folding chaperone
M	1990220	cellular_component	GroEL-GroES complex
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0006457	biological_process	protein folding
N	0009408	biological_process	response to heat
N	0016853	molecular_function	isomerase activity
N	0032727	biological_process	positive regulation of interferon-alpha production
N	0032729	biological_process	positive regulation of type II interferon production
N	0032755	biological_process	positive regulation of interleukin-6 production
N	0034514	biological_process	mitochondrial unfolded protein response
N	0042026	biological_process	protein refolding
N	0045041	biological_process	protein import into mitochondrial intermembrane space
N	0050870	biological_process	positive regulation of T cell activation
N	0051082	molecular_function	unfolded protein binding
N	0051085	biological_process	chaperone cofactor-dependent protein refolding
N	0051087	molecular_function	protein-folding chaperone binding
N	0140662	molecular_function	ATP-dependent protein folding chaperone
N	1990220	cellular_component	GroEL-GroES complex
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0006457	biological_process	protein folding
O	0009408	biological_process	response to heat
O	0016853	molecular_function	isomerase activity
O	0032727	biological_process	positive regulation of interferon-alpha production
O	0032729	biological_process	positive regulation of type II interferon production
O	0032755	biological_process	positive regulation of interleukin-6 production
O	0034514	biological_process	mitochondrial unfolded protein response
O	0042026	biological_process	protein refolding
O	0045041	biological_process	protein import into mitochondrial intermembrane space
O	0050870	biological_process	positive regulation of T cell activation
O	0051082	molecular_function	unfolded protein binding
O	0051085	biological_process	chaperone cofactor-dependent protein refolding
O	0051087	molecular_function	protein-folding chaperone binding
O	0140662	molecular_function	ATP-dependent protein folding chaperone
O	1990220	cellular_component	GroEL-GroES complex
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0006457	biological_process	protein folding
P	0009408	biological_process	response to heat
P	0016853	molecular_function	isomerase activity
P	0032727	biological_process	positive regulation of interferon-alpha production
P	0032729	biological_process	positive regulation of type II interferon production
P	0032755	biological_process	positive regulation of interleukin-6 production
P	0034514	biological_process	mitochondrial unfolded protein response
P	0042026	biological_process	protein refolding
P	0045041	biological_process	protein import into mitochondrial intermembrane space
P	0050870	biological_process	positive regulation of T cell activation
P	0051082	molecular_function	unfolded protein binding
P	0051085	biological_process	chaperone cofactor-dependent protein refolding
P	0051087	molecular_function	protein-folding chaperone binding
P	0140662	molecular_function	ATP-dependent protein folding chaperone
P	1990220	cellular_component	GroEL-GroES complex
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0006457	biological_process	protein folding
Q	0009408	biological_process	response to heat
Q	0016853	molecular_function	isomerase activity
Q	0032727	biological_process	positive regulation of interferon-alpha production
Q	0032729	biological_process	positive regulation of type II interferon production
Q	0032755	biological_process	positive regulation of interleukin-6 production
Q	0034514	biological_process	mitochondrial unfolded protein response
Q	0042026	biological_process	protein refolding
Q	0045041	biological_process	protein import into mitochondrial intermembrane space
Q	0050870	biological_process	positive regulation of T cell activation
Q	0051082	molecular_function	unfolded protein binding
Q	0051085	biological_process	chaperone cofactor-dependent protein refolding
Q	0051087	molecular_function	protein-folding chaperone binding
Q	0140662	molecular_function	ATP-dependent protein folding chaperone
Q	1990220	cellular_component	GroEL-GroES complex
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006457	biological_process	protein folding
R	0009408	biological_process	response to heat
R	0016853	molecular_function	isomerase activity
R	0032727	biological_process	positive regulation of interferon-alpha production
R	0032729	biological_process	positive regulation of type II interferon production
R	0032755	biological_process	positive regulation of interleukin-6 production
R	0034514	biological_process	mitochondrial unfolded protein response
R	0042026	biological_process	protein refolding
R	0045041	biological_process	protein import into mitochondrial intermembrane space
R	0050870	biological_process	positive regulation of T cell activation
R	0051082	molecular_function	unfolded protein binding
R	0051085	biological_process	chaperone cofactor-dependent protein refolding
R	0051087	molecular_function	protein-folding chaperone binding
R	0140662	molecular_function	ATP-dependent protein folding chaperone
R	1990220	cellular_component	GroEL-GroES complex
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006457	biological_process	protein folding
S	0009408	biological_process	response to heat
S	0016853	molecular_function	isomerase activity
S	0032727	biological_process	positive regulation of interferon-alpha production
S	0032729	biological_process	positive regulation of type II interferon production
S	0032755	biological_process	positive regulation of interleukin-6 production
S	0034514	biological_process	mitochondrial unfolded protein response
S	0042026	biological_process	protein refolding
S	0045041	biological_process	protein import into mitochondrial intermembrane space
S	0050870	biological_process	positive regulation of T cell activation
S	0051082	molecular_function	unfolded protein binding
S	0051085	biological_process	chaperone cofactor-dependent protein refolding
S	0051087	molecular_function	protein-folding chaperone binding
S	0140662	molecular_function	ATP-dependent protein folding chaperone
S	1990220	cellular_component	GroEL-GroES complex
T	0005524	molecular_function	ATP binding
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006457	biological_process	protein folding
T	0009408	biological_process	response to heat
T	0016853	molecular_function	isomerase activity
T	0032727	biological_process	positive regulation of interferon-alpha production
T	0032729	biological_process	positive regulation of type II interferon production
T	0032755	biological_process	positive regulation of interleukin-6 production
T	0034514	biological_process	mitochondrial unfolded protein response
T	0042026	biological_process	protein refolding
T	0045041	biological_process	protein import into mitochondrial intermembrane space
T	0050870	biological_process	positive regulation of T cell activation
T	0051082	molecular_function	unfolded protein binding
T	0051085	biological_process	chaperone cofactor-dependent protein refolding
T	0051087	molecular_function	protein-folding chaperone binding
T	0140662	molecular_function	ATP-dependent protein folding chaperone
T	1990220	cellular_component	GroEL-GroES complex
U	0005524	molecular_function	ATP binding
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006457	biological_process	protein folding
U	0009408	biological_process	response to heat
U	0016853	molecular_function	isomerase activity
U	0032727	biological_process	positive regulation of interferon-alpha production
U	0032729	biological_process	positive regulation of type II interferon production
U	0032755	biological_process	positive regulation of interleukin-6 production
U	0034514	biological_process	mitochondrial unfolded protein response
U	0042026	biological_process	protein refolding
U	0045041	biological_process	protein import into mitochondrial intermembrane space
U	0050870	biological_process	positive regulation of T cell activation
U	0051082	molecular_function	unfolded protein binding
U	0051085	biological_process	chaperone cofactor-dependent protein refolding
U	0051087	molecular_function	protein-folding chaperone binding
U	0140662	molecular_function	ATP-dependent protein folding chaperone
U	1990220	cellular_component	GroEL-GroES complex
V	0005524	molecular_function	ATP binding
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006457	biological_process	protein folding
V	0009408	biological_process	response to heat
V	0016853	molecular_function	isomerase activity
V	0032727	biological_process	positive regulation of interferon-alpha production
V	0032729	biological_process	positive regulation of type II interferon production
V	0032755	biological_process	positive regulation of interleukin-6 production
V	0034514	biological_process	mitochondrial unfolded protein response
V	0042026	biological_process	protein refolding
V	0045041	biological_process	protein import into mitochondrial intermembrane space
V	0050870	biological_process	positive regulation of T cell activation
V	0051082	molecular_function	unfolded protein binding
V	0051085	biological_process	chaperone cofactor-dependent protein refolding
V	0051087	molecular_function	protein-folding chaperone binding
V	0140662	molecular_function	ATP-dependent protein folding chaperone
V	1990220	cellular_component	GroEL-GroES complex
W	0005524	molecular_function	ATP binding
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0006457	biological_process	protein folding
W	0009408	biological_process	response to heat
W	0016853	molecular_function	isomerase activity
W	0032727	biological_process	positive regulation of interferon-alpha production
W	0032729	biological_process	positive regulation of type II interferon production
W	0032755	biological_process	positive regulation of interleukin-6 production
W	0034514	biological_process	mitochondrial unfolded protein response
W	0042026	biological_process	protein refolding
W	0045041	biological_process	protein import into mitochondrial intermembrane space
W	0050870	biological_process	positive regulation of T cell activation
W	0051082	molecular_function	unfolded protein binding
W	0051085	biological_process	chaperone cofactor-dependent protein refolding
W	0051087	molecular_function	protein-folding chaperone binding
W	0140662	molecular_function	ATP-dependent protein folding chaperone
W	1990220	cellular_component	GroEL-GroES complex
X	0005524	molecular_function	ATP binding
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0006457	biological_process	protein folding
X	0009408	biological_process	response to heat
X	0016853	molecular_function	isomerase activity
X	0032727	biological_process	positive regulation of interferon-alpha production
X	0032729	biological_process	positive regulation of type II interferon production
X	0032755	biological_process	positive regulation of interleukin-6 production
X	0034514	biological_process	mitochondrial unfolded protein response
X	0042026	biological_process	protein refolding
X	0045041	biological_process	protein import into mitochondrial intermembrane space
X	0050870	biological_process	positive regulation of T cell activation
X	0051082	molecular_function	unfolded protein binding
X	0051085	biological_process	chaperone cofactor-dependent protein refolding
X	0051087	molecular_function	protein-folding chaperone binding
X	0140662	molecular_function	ATP-dependent protein folding chaperone
X	1990220	cellular_component	GroEL-GroES complex
Y	0005524	molecular_function	ATP binding
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0006457	biological_process	protein folding
Y	0009408	biological_process	response to heat
Y	0016853	molecular_function	isomerase activity
Y	0032727	biological_process	positive regulation of interferon-alpha production
Y	0032729	biological_process	positive regulation of type II interferon production
Y	0032755	biological_process	positive regulation of interleukin-6 production
Y	0034514	biological_process	mitochondrial unfolded protein response
Y	0042026	biological_process	protein refolding
Y	0045041	biological_process	protein import into mitochondrial intermembrane space
Y	0050870	biological_process	positive regulation of T cell activation
Y	0051082	molecular_function	unfolded protein binding
Y	0051085	biological_process	chaperone cofactor-dependent protein refolding
Y	0051087	molecular_function	protein-folding chaperone binding
Y	0140662	molecular_function	ATP-dependent protein folding chaperone
Y	1990220	cellular_component	GroEL-GroES complex
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0006457	biological_process	protein folding
Z	0009408	biological_process	response to heat
Z	0016853	molecular_function	isomerase activity
Z	0032727	biological_process	positive regulation of interferon-alpha production
Z	0032729	biological_process	positive regulation of type II interferon production
Z	0032755	biological_process	positive regulation of interleukin-6 production
Z	0034514	biological_process	mitochondrial unfolded protein response
Z	0042026	biological_process	protein refolding
Z	0045041	biological_process	protein import into mitochondrial intermembrane space
Z	0050870	biological_process	positive regulation of T cell activation
Z	0051082	molecular_function	unfolded protein binding
Z	0051085	biological_process	chaperone cofactor-dependent protein refolding
Z	0051087	molecular_function	protein-folding chaperone binding
Z	0140662	molecular_function	ATP-dependent protein folding chaperone
Z	1990220	cellular_component	GroEL-GroES complex
a	0005524	molecular_function	ATP binding
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006457	biological_process	protein folding
a	0009408	biological_process	response to heat
a	0016853	molecular_function	isomerase activity
a	0032727	biological_process	positive regulation of interferon-alpha production
a	0032729	biological_process	positive regulation of type II interferon production
a	0032755	biological_process	positive regulation of interleukin-6 production
a	0034514	biological_process	mitochondrial unfolded protein response
a	0042026	biological_process	protein refolding
a	0045041	biological_process	protein import into mitochondrial intermembrane space
a	0050870	biological_process	positive regulation of T cell activation
a	0051082	molecular_function	unfolded protein binding
a	0051085	biological_process	chaperone cofactor-dependent protein refolding
a	0051087	molecular_function	protein-folding chaperone binding
a	0140662	molecular_function	ATP-dependent protein folding chaperone
a	1990220	cellular_component	GroEL-GroES complex
b	0005524	molecular_function	ATP binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006457	biological_process	protein folding
b	0009408	biological_process	response to heat
b	0016853	molecular_function	isomerase activity
b	0032727	biological_process	positive regulation of interferon-alpha production
b	0032729	biological_process	positive regulation of type II interferon production
b	0032755	biological_process	positive regulation of interleukin-6 production
b	0034514	biological_process	mitochondrial unfolded protein response
b	0042026	biological_process	protein refolding
b	0045041	biological_process	protein import into mitochondrial intermembrane space
b	0050870	biological_process	positive regulation of T cell activation
b	0051082	molecular_function	unfolded protein binding
b	0051085	biological_process	chaperone cofactor-dependent protein refolding
b	0051087	molecular_function	protein-folding chaperone binding
b	0140662	molecular_function	ATP-dependent protein folding chaperone
b	1990220	cellular_component	GroEL-GroES complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 601

Chain	Residue
A	LEU31
A	ASP87
A	GLY88
A	THR90
A	THR91

---

site_id	AC2
Number of Residues	2
Details	binding site for residue CA A 602

Chain	Residue
A	LYS42
A	LYS43

---

site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 B 601

Chain	Residue
B	GLY88
B	THR89
B	THR90
B	THR91
B	LEU31
B	ASP87

---

site_id	AC4
Number of Residues	1
Details	binding site for residue CA B 602

Chain	Residue
B	LYS43

---

site_id	AC5
Number of Residues	5
Details	binding site for residue SO4 C 601

Chain	Residue
C	LEU31
C	ASP87
C	GLY88
C	THR90
C	THR91

---

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 D 601

Chain	Residue
D	LEU31
D	ASP87
D	GLY88
D	THR89
D	THR90
D	THR91

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 E 601

Chain	Residue
E	ASP87
E	GLY88
E	THR89
E	THR90
E	THR91

---

site_id	AC8
Number of Residues	6
Details	binding site for residue SO4 F 601

Chain	Residue
F	LEU31
F	ASP87
F	GLY88
F	THR89
F	THR90
F	THR91

---

site_id	AC9
Number of Residues	1
Details	binding site for residue CA F 602

Chain	Residue
F	LYS43

---

site_id	AD1
Number of Residues	6
Details	binding site for residue SO4 G 601

Chain	Residue
G	LEU31
G	ASP87
G	GLY88
G	THR89
G	THR90
G	THR91

---

site_id	AD2
Number of Residues	3
Details	binding site for residue MG H 601

Chain	Residue
H	THR30
H	GLY32
H	LYS51

---

site_id	AD3
Number of Residues	6
Details	binding site for residue SO4 J 601

Chain	Residue
J	LEU31
J	ASP87
J	GLY88
J	THR89
J	THR90
J	THR91

---

site_id	AD4
Number of Residues	2
Details	binding site for residue CA J 602

Chain	Residue
J	LYS42
J	LYS43

---

site_id	AD5
Number of Residues	6
Details	binding site for residue SO4 K 601

Chain	Residue
K	LEU31
K	ASP87
K	GLY88
K	THR89
K	THR90
K	THR91

---

site_id	AD6
Number of Residues	2
Details	binding site for residue CA K 602

Chain	Residue
K	LYS42
K	LYS43

---

site_id	AD7
Number of Residues	6
Details	binding site for residue SO4 L 601

Chain	Residue
L	LEU31
L	ASP87
L	GLY88
L	THR89
L	THR90
L	THR91

---

site_id	AD8
Number of Residues	2
Details	binding site for residue MG M 601

Chain	Residue
M	THR30
M	LYS51

---

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 M 602

Chain	Residue
M	LEU31
M	ASP87
M	THR90

---

site_id	AE1
Number of Residues	1
Details	binding site for residue CA M 603

Chain	Residue
M	LYS43

---

site_id	AE2
Number of Residues	5
Details	binding site for residue SO4 N 601

Chain	Residue
N	LEU31
N	ASP87
N	GLY88
N	THR90
N	THR91

---

site_id	AE3
Number of Residues	1
Details	binding site for residue CA O 601

Chain	Residue
O	LYS43

---

site_id	AE4
Number of Residues	6
Details	binding site for residue SO4 P 601

Chain	Residue
P	LEU31
P	ASP87
P	GLY88
P	THR90
P	THR91
P	HOH702

---

site_id	AE5
Number of Residues	2
Details	binding site for residue MG Q 601

Chain	Residue
Q	THR30
Q	LYS51

---

site_id	AE6
Number of Residues	3
Details	binding site for residue MG R 601

Chain	Residue
R	THR30
R	GLY32
R	LYS51

---

site_id	AE7
Number of Residues	6
Details	binding site for residue SO4 R 602

Chain	Residue
R	LEU31
R	ASP87
R	GLY88
R	THR89
R	THR90
R	THR91

---

site_id	AE8
Number of Residues	2
Details	binding site for residue CA R 603

Chain	Residue
R	LYS42
R	LYS43

---

site_id	AE9
Number of Residues	3
Details	binding site for residue MG S 601

Chain	Residue
S	THR30
S	GLY32
S	LYS51

---

site_id	AF1
Number of Residues	1
Details	binding site for residue MG T 601

Chain	Residue
T	GLY32

---

site_id	AF2
Number of Residues	6
Details	binding site for residue SO4 T 602

Chain	Residue
T	LEU31
T	ASP87
T	GLY88
T	THR89
T	THR90
T	THR91

---

site_id	AF3
Number of Residues	5
Details	binding site for residue SO4 U 601

Chain	Residue
U	ASP87
U	GLY88
U	THR89
U	THR90
U	THR91

---

site_id	AF4
Number of Residues	2
Details	binding site for residue MG V 601

Chain	Residue
V	THR30
V	LYS51

---

site_id	AF5
Number of Residues	6
Details	binding site for residue SO4 V 602

Chain	Residue
V	LEU31
V	ASP87
V	GLY88
V	THR89
V	THR90
V	THR91

---

site_id	AF6
Number of Residues	6
Details	binding site for residue SO4 Y 601

Chain	Residue
Y	LEU31
Y	ASP87
Y	GLY88
Y	THR89
Y	THR90
Y	THR91

---

site_id	AF7
Number of Residues	4
Details	binding site for residue SO4 Z 601

Chain	Residue
Z	LEU31
Z	ASP87
Z	GLY88
Z	THR91

---

site_id	AF8
Number of Residues	1
Details	binding site for residue CA Z 602

Chain	Residue
Z	LYS43

---

site_id	AF9
Number of Residues	6
Details	binding site for residue SO4 a 601

Chain	Residue
a	LEU31
a	ASP87
a	GLY88
a	THR89
a	THR90
a	THR91

---

site_id	AG1
Number of Residues	6
Details	binding site for residue SO4 b 601

Chain	Residue
b	LEU31
b	ASP87
b	GLY88
b	THR89
b	THR90
b	THR91

---

Functional Information from PROSITE/UniProt

site_id	PS00296
Number of Residues	12
Details	CHAPERONINS_CPN60 Chaperonins cpn60 signature. AAVQEGIVvGGG

Chain	Residue	Details
A	ALA405-GLY416

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	140
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00600

Chain	Residue	Details
L	LYS51
L	ASP87
L	GLY415
L	ASP496
M	THR30
M	LYS51
M	ASP87
M	GLY415
M	ASP496
N	THR30
N	LYS51
N	ASP87
N	GLY415
N	ASP496
O	THR30
O	LYS51
O	ASP87
O	GLY415
O	ASP496
P	THR30
P	LYS51
P	ASP87
P	GLY415
P	ASP496
Q	THR30
Q	LYS51
Q	ASP87
Q	GLY415
Q	ASP496
R	THR30
R	LYS51
R	ASP87
R	GLY415
R	ASP496
S	THR30
S	LYS51
S	ASP87
S	GLY415
S	ASP496
T	THR30
T	LYS51
T	ASP87
T	GLY415
T	ASP496
U	THR30
U	LYS51
U	ASP87
U	GLY415
U	ASP496
V	THR30
V	LYS51
V	ASP87
V	GLY415
V	ASP496
W	THR30
W	LYS51
W	ASP87
W	GLY415
W	ASP496
X	THR30
X	LYS51
X	ASP87
X	GLY415
X	ASP496
Y	THR30
Y	LYS51
Y	ASP87
Y	GLY415
Y	ASP496
Z	THR30
Z	LYS51
Z	ASP87
Z	GLY415
Z	ASP496
a	THR30
a	LYS51
a	ASP87
a	GLY415
a	ASP496
b	THR30
b	LYS51
b	ASP87
b	GLY415
b	ASP496
A	THR30
A	LYS51
A	ASP87
A	GLY415
A	ASP496
B	THR30
B	LYS51
B	ASP87
B	GLY415
B	ASP496
C	THR30
C	LYS51
C	ASP87
C	GLY415
C	ASP496
D	THR30
D	LYS51
D	ASP87
D	GLY415
D	ASP496
E	THR30
E	LYS51
E	ASP87
E	GLY415
E	ASP496
F	THR30
F	LYS51
F	ASP87
F	GLY415
F	ASP496
G	THR30
G	LYS51
G	ASP87
G	GLY415
G	ASP496
H	THR30
H	LYS51
H	ASP87
H	GLY415
H	ASP496
I	THR30
I	LYS51
I	ASP87
I	GLY415
I	ASP496
J	THR30
J	LYS51
J	ASP87
J	GLY415
J	ASP496
K	THR30
K	LYS51
K	ASP87
K	GLY415
K	ASP496
L	THR30

---