Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5BRX

X-ray crystal structure of Aplysia californica (Ac-AChBP) in complex with 2-pyridyl azatricyclo[3.3.1.13,7]decane; 2-pyridylazaadamantane; 2-Aza (TI-8480)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue SO4 A 301

Chain	Residue
A	LYS42
B	ARG97
B	HOH412

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 A 302

Chain	Residue
A	ARG97
A	HOH405
A	HOH452
E	LYS42

site_id	AC3
Number of Residues	7
Details	binding site for residue TI4 A 303

Chain	Residue
A	TYR188
A	CYS190
A	TYR195
E	TRP55
E	HOH428
A	TRP147
A	VAL148

site_id	AC4
Number of Residues	4
Details	binding site for residue PG4 A 304

Chain	Residue
A	TRP55
A	GLN57
B	CYS190
B	TYR195

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 B 301

Chain	Residue
B	LYS42
C	ARG97
C	HOH408

site_id	AC6
Number of Residues	3
Details	binding site for residue SO4 C 301

Chain	Residue
C	LYS42
D	ARG97
D	HOH415

site_id	AC7
Number of Residues	4
Details	binding site for residue PG4 C 302

Chain	Residue
C	TRP147
C	TYR188
C	CYS191
C	TYR195

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 D 301

Chain	Residue
D	LYS42
E	ARG97
E	HOH404

site_id	AC9
Number of Residues	6
Details	binding site for residue TI4 D 302

Chain	Residue
C	TRP55
C	HOH436
D	TRP147
D	TYR188
D	CYS190
D	TYR195

site_id	AD1
Number of Residues	1
Details	binding site for residue PG4 E 301

Chain	Residue
E	TYR195

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 F 301

Chain	Residue
F	LYS42
F	HOH420
G	ARG97

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 F 302

Chain	Residue
F	ARG97
F	HOH405
J	LYS42

site_id	AD4
Number of Residues	6
Details	binding site for residue TI4 F 303

Chain	Residue
F	TRP147
F	TYR188
F	CYS190
F	TYR195
J	TRP55
J	HOH426

site_id	AD5
Number of Residues	6
Details	binding site for residue PG4 F 304

Chain	Residue
F	TRP55
F	GLN57
F	ILE118
F	SER167
F	HOH446
G	CYS191

site_id	AD6
Number of Residues	3
Details	binding site for residue SO4 G 301

Chain	Residue
G	LYS42
H	ARG97
H	HOH406

site_id	AD7
Number of Residues	3
Details	binding site for residue SO4 H 301

Chain	Residue
H	LYS42
I	ARG97
I	HOH414

site_id	AD8
Number of Residues	3
Details	binding site for residue PG4 H 302

Chain	Residue
G	ILE118
H	TRP147
H	TYR195

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 I 301

Chain	Residue
I	LYS42
J	ARG97
J	HOH407

site_id	AE1
Number of Residues	5
Details	binding site for residue TI4 I 302

Chain	Residue
H	TRP55
I	TRP147
I	TYR188
I	CYS190
I	TYR195

site_id	AE2
Number of Residues	2
Details	binding site for residue PG4 J 301

Chain	Residue
J	TRP147
J	TYR195

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)