5B7M

Structure of perdeuterated CueO - the signal peptide was truncated by HRV3C protease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005507	molecular_function	copper ion binding
A	0010273	biological_process	detoxification of copper ion
A	0016491	molecular_function	oxidoreductase activity
A	0016682	molecular_function	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A	0016722	molecular_function	oxidoreductase activity, acting on metal ions
A	0016724	molecular_function	oxidoreductase activity, acting on metal ions, oxygen as acceptor
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042597	cellular_component	periplasmic space
A	0046688	biological_process	response to copper ion
A	0046872	molecular_function	metal ion binding
B	0004322	molecular_function	ferroxidase activity
B	0005507	molecular_function	copper ion binding
B	0010273	biological_process	detoxification of copper ion
B	0016491	molecular_function	oxidoreductase activity
B	0016682	molecular_function	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B	0016722	molecular_function	oxidoreductase activity, acting on metal ions
B	0016724	molecular_function	oxidoreductase activity, acting on metal ions, oxygen as acceptor
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0042597	cellular_component	periplasmic space
B	0046688	biological_process	response to copper ion
B	0046872	molecular_function	metal ion binding
C	0004322	molecular_function	ferroxidase activity
C	0005507	molecular_function	copper ion binding
C	0010273	biological_process	detoxification of copper ion
C	0016491	molecular_function	oxidoreductase activity
C	0016682	molecular_function	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C	0016722	molecular_function	oxidoreductase activity, acting on metal ions
C	0016724	molecular_function	oxidoreductase activity, acting on metal ions, oxygen as acceptor
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0042597	cellular_component	periplasmic space
C	0046688	biological_process	response to copper ion
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CU A 601

Chain	Residue
A	HIS443
A	CYS500
A	HIS505
A	MET510

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CU A 602

Chain	Residue
A	HOH936
A	HIS143
A	HIS446
A	HIS448
A	HIS499
A	CU604

---

site_id	AC3
Number of Residues	5
Details	binding site for residue CU A 603

Chain	Residue
A	HIS103
A	TRP139
A	HIS141
A	HIS501
A	HOH936

---

site_id	AC4
Number of Residues	7
Details	binding site for residue CU A 604

Chain	Residue
A	HIS101
A	HIS103
A	HIS446
A	HIS448
A	CU602
A	HOH798
A	HOH936

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CU B 601

Chain	Residue
B	HIS443
B	CYS500
B	HIS505
B	MET510

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CU B 602

Chain	Residue
B	HIS143
B	HIS446
B	HIS448
B	HIS499
B	CU604
B	HOH931

---

site_id	AC7
Number of Residues	5
Details	binding site for residue CU B 603

Chain	Residue
B	HIS103
B	TRP139
B	HIS141
B	HIS501
B	HOH931

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CU B 604

Chain	Residue
B	HIS101
B	HIS103
B	HIS446
B	HIS448
B	CU602
B	HOH931

---

site_id	AC9
Number of Residues	4
Details	binding site for residue CU C 601

Chain	Residue
C	HIS443
C	CYS500
C	HIS505
C	MET510

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CU C 602

Chain	Residue
C	HIS143
C	HIS446
C	HIS448
C	HIS499
C	CU604
C	HOH837

---

site_id	AD2
Number of Residues	6
Details	binding site for residue CU C 603

Chain	Residue
C	HIS103
C	TRP139
C	HIS141
C	HIS501
C	CU604
C	HOH837

---

site_id	AD3
Number of Residues	7
Details	binding site for residue CU C 604

Chain	Residue
C	HIS101
C	HIS103
C	HIS446
C	HIS448
C	CU602
C	CU603
C	HOH837

---

Functional Information from PROSITE/UniProt

site_id	PS00080
Number of Residues	12
Details	MULTICOPPER_OXIDASE2 Multicopper oxidases signature 2. HCHlleHedtGM

Chain	Residue	Details
A	HIS499-MET510

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: type 2 copper site => ECO:0000269|PubMed:11867755, ECO:0000269|PubMed:12794077, ECO:0000269|PubMed:17217912, ECO:0000269|PubMed:17804014, ECO:0000269|PubMed:21903583, ECO:0000269|PubMed:24598746, ECO:0007744|PDB:1KV7, ECO:0007744|PDB:1N68, ECO:0007744|PDB:1PF3, ECO:0007744|PDB:2FQE, ECO:0007744|PDB:2FQF, ECO:0007744|PDB:2FQG, ECO:0007744|PDB:2YXV, ECO:0007744|PDB:2YXW

Chain	Residue	Details
A	HIS101
A	HIS446
B	HIS101
B	HIS446
C	HIS101
C	HIS446

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	BINDING: type 3 copper site => ECO:0000269|PubMed:11867755, ECO:0000269|PubMed:12794077, ECO:0000269|PubMed:17217912, ECO:0000269|PubMed:17804014, ECO:0000269|PubMed:21903583, ECO:0000269|PubMed:24598746, ECO:0007744|PDB:1KV7, ECO:0007744|PDB:1N68, ECO:0007744|PDB:1PF3, ECO:0007744|PDB:2FQD, ECO:0007744|PDB:2FQE, ECO:0007744|PDB:2FQF, ECO:0007744|PDB:2FQG, ECO:0007744|PDB:2YXV, ECO:0007744|PDB:2YXW

Chain	Residue	Details
A	HIS103
B	HIS448
B	HIS499
B	HIS501
C	HIS103
C	HIS141
C	HIS143
C	HIS448
C	HIS499
C	HIS501
A	HIS141
A	HIS143
A	HIS448
A	HIS499
A	HIS501
B	HIS103
B	HIS141
B	HIS143

---

site_id	SWS_FT_FI3
Number of Residues	9
Details	BINDING: type 1 copper site => ECO:0000269|PubMed:11867755, ECO:0000269|PubMed:12794077, ECO:0000269|PubMed:17217912, ECO:0000269|PubMed:17804014, ECO:0000269|PubMed:21903583, ECO:0000269|PubMed:24598746, ECO:0007744|PDB:1KV7, ECO:0007744|PDB:1N68, ECO:0007744|PDB:1PF3, ECO:0007744|PDB:2FQD, ECO:0007744|PDB:2FQE, ECO:0007744|PDB:2FQF, ECO:0007744|PDB:2FQG, ECO:0007744|PDB:2YXV, ECO:0007744|PDB:2YXW

Chain	Residue	Details
A	HIS443
A	CYS500
A	HIS505
B	HIS443
B	CYS500
B	HIS505
C	HIS443
C	CYS500
C	HIS505

---