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5A5W

Crystal structure of Salmonella enterica HisA D7N D176A with ProFAR

Functional Information from GO Data
ChainGOidnamespacecontents
A0000105biological_processhistidine biosynthetic process
A0000162biological_processtryptophan biosynthetic process
A0003949molecular_function1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
A0005737cellular_componentcytoplasm
A0008652biological_processamino acid biosynthetic process
A0016853molecular_functionisomerase activity
Functional Information from PDB Data
site_idAC1
Number of Residues31
DetailsBINDING SITE FOR RESIDUE GUO A 1246
ChainResidue
AASN7
AGLY102
ASER103
AASP129
AGLY144
ATRP145
AGLY177
ASER202
AGLY203
AGLY204
AILE223
AGLY19
AGLY225
AARG226
AHOH2070
AHOH2075
AHOH2095
AHOH2096
AHOH2145
AHOH2169
AHOH2190
AHOH2191
AHIS47
AHOH2210
AHOH2211
AVAL49
ALEU51
AGLY80
AGLY81
AARG83
AVAL100

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000250
ChainResidueDetails
AASN7

site_idSWS_FT_FI2
Number of Residues1
DetailsACT_SITE: Proton donor => ECO:0000250
ChainResidueDetails
AASP129

221051

PDB entries from 2024-06-12

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