Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4ZJQ

Crystal structure of AcrB deletion mutant in complex with antibiotic in P21 space group

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0015562molecular_functionefflux transmembrane transporter activity
A0016020cellular_componentmembrane
A0022857molecular_functiontransmembrane transporter activity
A0030288cellular_componentouter membrane-bounded periplasmic space
A0042802molecular_functionidentical protein binding
A0042908biological_processxenobiotic transport
A0042910molecular_functionxenobiotic transmembrane transporter activity
A0055085biological_processtransmembrane transport
A0098567cellular_componentperiplasmic side of plasma membrane
A0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
A1990281cellular_componentefflux pump complex
B0005515molecular_functionprotein binding
B0005886cellular_componentplasma membrane
B0015562molecular_functionefflux transmembrane transporter activity
B0016020cellular_componentmembrane
B0022857molecular_functiontransmembrane transporter activity
B0030288cellular_componentouter membrane-bounded periplasmic space
B0042802molecular_functionidentical protein binding
B0042908biological_processxenobiotic transport
B0042910molecular_functionxenobiotic transmembrane transporter activity
B0055085biological_processtransmembrane transport
B0098567cellular_componentperiplasmic side of plasma membrane
B0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
B1990281cellular_componentefflux pump complex
C0005515molecular_functionprotein binding
C0005886cellular_componentplasma membrane
C0015562molecular_functionefflux transmembrane transporter activity
C0016020cellular_componentmembrane
C0022857molecular_functiontransmembrane transporter activity
C0030288cellular_componentouter membrane-bounded periplasmic space
C0042802molecular_functionidentical protein binding
C0042908biological_processxenobiotic transport
C0042910molecular_functionxenobiotic transmembrane transporter activity
C0055085biological_processtransmembrane transport
C0098567cellular_componentperiplasmic side of plasma membrane
C0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
C1990281cellular_componentefflux pump complex
D0005515molecular_functionprotein binding
D0005886cellular_componentplasma membrane
D0015562molecular_functionefflux transmembrane transporter activity
D0016020cellular_componentmembrane
D0022857molecular_functiontransmembrane transporter activity
D0030288cellular_componentouter membrane-bounded periplasmic space
D0042802molecular_functionidentical protein binding
D0042908biological_processxenobiotic transport
D0042910molecular_functionxenobiotic transmembrane transporter activity
D0055085biological_processtransmembrane transport
D0098567cellular_componentperiplasmic side of plasma membrane
D0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
D1990281cellular_componentefflux pump complex
E0005515molecular_functionprotein binding
E0005886cellular_componentplasma membrane
E0015562molecular_functionefflux transmembrane transporter activity
E0016020cellular_componentmembrane
E0022857molecular_functiontransmembrane transporter activity
E0030288cellular_componentouter membrane-bounded periplasmic space
E0042802molecular_functionidentical protein binding
E0042908biological_processxenobiotic transport
E0042910molecular_functionxenobiotic transmembrane transporter activity
E0055085biological_processtransmembrane transport
E0098567cellular_componentperiplasmic side of plasma membrane
E0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
E1990281cellular_componentefflux pump complex
F0005515molecular_functionprotein binding
F0005886cellular_componentplasma membrane
F0015562molecular_functionefflux transmembrane transporter activity
F0016020cellular_componentmembrane
F0022857molecular_functiontransmembrane transporter activity
F0030288cellular_componentouter membrane-bounded periplasmic space
F0042802molecular_functionidentical protein binding
F0042908biological_processxenobiotic transport
F0042910molecular_functionxenobiotic transmembrane transporter activity
F0055085biological_processtransmembrane transport
F0098567cellular_componentperiplasmic side of plasma membrane
F0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
F1990281cellular_componentefflux pump complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues924
DetailsTOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:15919996
ChainResidueDetails
AMET1-PRO9
BGLU414-ILE438
BALA491-THR538
BSER889-LEU898
BALA944-MET972
CMET1-PRO9
CLEU357-THR365
CGLU414-ILE438
CALA491-THR538
CSER889-LEU898
ALEU357-THR365
CALA944-MET972
DMET1-PRO9
DLEU357-THR365
DGLU414-ILE438
DALA491-THR538
DSER889-LEU898
DALA944-MET972
EMET1-PRO9
AGLU414-ILE438
ELEU357-THR365
EGLU414-ILE438
EALA491-THR538
ESER889-LEU898
EALA944-MET972
FMET1-PRO9
FLEU357-THR365
FGLU414-ILE438
FALA491-THR538
AALA491-THR538
FSER889-LEU898
FALA944-MET972
ASER889-LEU898
AALA944-MET972
BMET1-PRO9
BLEU357-THR365

site_idSWS_FT_FI2
Number of Residues108
DetailsTRANSMEM: Helical; Name=1
ChainResidueDetails
AILE10-LEU28
BILE10-LEU28
CILE10-LEU28
DILE10-LEU28
EILE10-LEU28
FILE10-LEU28

site_idSWS_FT_FI3
Number of Residues3864
DetailsTOPO_DOM: Periplasmic => ECO:0000269|PubMed:15919996
ChainResidueDetails
ALYS29-SER336
BPHE556-LEU871
BASP919-VAL924
BGLY993-VAL998
CLYS29-SER336
CPHE386-ASN391
CPHE458-ALA465
CPHE556-LEU871
CASP919-VAL924
CGLY993-VAL998
DLYS29-SER336
APHE386-ASN391
DPHE386-ASN391
DPHE458-ALA465
DPHE556-LEU871
DASP919-VAL924
DGLY993-VAL998
ELYS29-SER336
EPHE386-ASN391
EPHE458-ALA465
EPHE556-LEU871
EASP919-VAL924
APHE458-ALA465
EGLY993-VAL998
FLYS29-SER336
FPHE386-ASN391
FPHE458-ALA465
FPHE556-LEU871
FASP919-VAL924
FGLY993-VAL998
APHE556-LEU871
AASP919-VAL924
AGLY993-VAL998
BLYS29-SER336
BPHE386-ASN391
BPHE458-ALA465

site_idSWS_FT_FI4
Number of Residues114
DetailsTRANSMEM: Helical; Name=2
ChainResidueDetails
AILE337-TYR356
BILE337-TYR356
CILE337-TYR356
DILE337-TYR356
EILE337-TYR356
FILE337-TYR356

site_idSWS_FT_FI5
Number of Residues114
DetailsTRANSMEM: Helical; Name=3
ChainResidueDetails
ALEU366-ALA385
BLEU366-ALA385
CLEU366-ALA385
DLEU366-ALA385
ELEU366-ALA385
FLEU366-ALA385

site_idSWS_FT_FI6
Number of Residues126
DetailsTRANSMEM: Helical; Name=4
ChainResidueDetails
ATHR392-VAL413
BTHR392-VAL413
CTHR392-VAL413
DTHR392-VAL413
ETHR392-VAL413
FTHR392-VAL413

site_idSWS_FT_FI7
Number of Residues108
DetailsTRANSMEM: Helical; Name=5
ChainResidueDetails
AGLN439-ALA457
BGLN439-ALA457
CGLN439-ALA457
DGLN439-ALA457
EGLN439-ALA457
FGLN439-ALA457

site_idSWS_FT_FI8
Number of Residues144
DetailsTRANSMEM: Helical; Name=6
ChainResidueDetails
AILE466-PRO490
BILE466-PRO490
CILE466-PRO490
DILE466-PRO490
EILE466-PRO490
FILE466-PRO490

site_idSWS_FT_FI9
Number of Residues96
DetailsTRANSMEM: Helical; Name=7
ChainResidueDetails
AGLY539-LEU555
BGLY539-LEU555
CGLY539-LEU555
DGLY539-LEU555
EGLY539-LEU555
FGLY539-LEU555

site_idSWS_FT_FI10
Number of Residues96
DetailsTRANSMEM: Helical; Name=8
ChainResidueDetails
ATYR872-GLU888
BTYR872-GLU888
CTYR872-GLU888
DTYR872-GLU888
ETYR872-GLU888
FTYR872-GLU888

site_idSWS_FT_FI11
Number of Residues114
DetailsTRANSMEM: Helical; Name=9
ChainResidueDetails
AVAL899-ASN918
BVAL899-ASN918
CVAL899-ASN918
DVAL899-ASN918
EVAL899-ASN918
FVAL899-ASN918

site_idSWS_FT_FI12
Number of Residues108
DetailsTRANSMEM: Helical; Name=10
ChainResidueDetails
AGLY925-PHE943
BGLY925-PHE943
CGLY925-PHE943
DGLY925-PHE943
EGLY925-PHE943
FGLY925-PHE943

site_idSWS_FT_FI13
Number of Residues114
DetailsTRANSMEM: Helical; Name=11
ChainResidueDetails
ATHR973-SER992
BTHR973-SER992
CTHR973-SER992
DTHR973-SER992
ETHR973-SER992
FTHR973-SER992

site_idSWS_FT_FI14
Number of Residues114
DetailsTRANSMEM: Helical; Name=12
ChainResidueDetails
AGLY999-PRO1018
BGLY999-PRO1018
CGLY999-PRO1018
DGLY999-PRO1018
EGLY999-PRO1018
FGLY999-PRO1018

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon