Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4XRA

Salmonella typhimurium AhpC T43S mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0008379	molecular_function	thioredoxin peroxidase activity
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0045454	biological_process	cell redox homeostasis
A	0051920	molecular_function	peroxiredoxin activity
A	0098869	biological_process	cellular oxidant detoxification
A	0102039	molecular_function	NADH-dependent peroxiredoxin activity
B	0004601	molecular_function	peroxidase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006979	biological_process	response to oxidative stress
B	0008379	molecular_function	thioredoxin peroxidase activity
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0045454	biological_process	cell redox homeostasis
B	0051920	molecular_function	peroxiredoxin activity
B	0098869	biological_process	cellular oxidant detoxification
B	0102039	molecular_function	NADH-dependent peroxiredoxin activity
C	0004601	molecular_function	peroxidase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006979	biological_process	response to oxidative stress
C	0008379	molecular_function	thioredoxin peroxidase activity
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0045454	biological_process	cell redox homeostasis
C	0051920	molecular_function	peroxiredoxin activity
C	0098869	biological_process	cellular oxidant detoxification
C	0102039	molecular_function	NADH-dependent peroxiredoxin activity
D	0004601	molecular_function	peroxidase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006979	biological_process	response to oxidative stress
D	0008379	molecular_function	thioredoxin peroxidase activity
D	0016209	molecular_function	antioxidant activity
D	0016491	molecular_function	oxidoreductase activity
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0045454	biological_process	cell redox homeostasis
D	0051920	molecular_function	peroxiredoxin activity
D	0098869	biological_process	cellular oxidant detoxification
D	0102039	molecular_function	NADH-dependent peroxiredoxin activity
E	0004601	molecular_function	peroxidase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006979	biological_process	response to oxidative stress
E	0008379	molecular_function	thioredoxin peroxidase activity
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0042744	biological_process	hydrogen peroxide catabolic process
E	0045454	biological_process	cell redox homeostasis
E	0051920	molecular_function	peroxiredoxin activity
E	0098869	biological_process	cellular oxidant detoxification
E	0102039	molecular_function	NADH-dependent peroxiredoxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CL A 201

Chain	Residue
A	SER1
A	LEU2
A	HOH338
B	HOH344

site_id	AC2
Number of Residues	4
Details	binding site for residue CL A 202

Chain	Residue
A	THR100
A	HOH321
A	HOH321
A	HOH322

site_id	AC3
Number of Residues	3
Details	binding site for residue CL A 203

Chain	Residue
C	GLY18
C	LYS79
A	CYS165

site_id	AC4
Number of Residues	6
Details	binding site for residue K A 204

Chain	Residue
A	THR72
A	THR72
A	HOH306
A	HOH306
A	HOH312
A	HOH312

site_id	AC5
Number of Residues	8
Details	binding site for residue SO4 B 201

Chain	Residue
A	LYS168
B	CYS46
B	PRO47
B	SER85
B	GLU86
B	THR87
B	HOH331
B	HOH474

site_id	AC6
Number of Residues	4
Details	binding site for residue CL B 202

Chain	Residue
B	SER1
B	LEU2
B	HOH326
B	HOH344

site_id	AC7
Number of Residues	6
Details	binding site for residue K B 203

Chain	Residue
B	THR72
B	HOH345
B	HOH351
C	THR72
C	HOH319
C	HOH322

site_id	AC8
Number of Residues	5
Details	binding site for residue CL C 201

Chain	Residue
C	SER1
C	LEU2
C	HOH355
D	HOH325
D	HOH343

site_id	AC9
Number of Residues	7
Details	binding site for residue CL C 202

Chain	Residue
B	ARG105
B	HOH434
B	HOH446
B	HOH460
C	ARG105
C	HOH392
C	HOH429

site_id	AD1
Number of Residues	6
Details	binding site for residue CL D 201

Chain	Residue
D	SER1
D	LEU2
D	ILE133
D	HOH338
D	HOH343
D	HOH390

site_id	AD2
Number of Residues	7
Details	binding site for residue CL D 202

Chain	Residue
D	ARG105
D	HOH361
D	HOH461
E	ARG105
E	HOH372
E	HOH380
E	HOH383

site_id	AD3
Number of Residues	6
Details	binding site for residue K D 203

Chain	Residue
D	THR72
D	HOH336
D	HOH418
E	THR72
E	HOH336
E	HOH337

site_id	AD4
Number of Residues	6
Details	binding site for residue CL E 201

Chain	Residue
E	SER1
E	LEU2
E	HOH312
E	HOH316
E	HOH328
E	HOH328

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000305\|PubMed:18986167

Chain	Residue	Details
A	CYS46
B	CYS46
C	CYS46
D	CYS46
E	CYS46

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)