Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008395 | molecular_function | steroid hydroxylase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 18 |
Details | binding site for residue HEM A 501 |
Chain | Residue |
A | LEU89 |
A | THR244 |
A | GLY289 |
A | ILE291 |
A | ARG294 |
A | ALA345 |
A | PHE346 |
A | HIS351 |
A | CYS353 |
A | GLY355 |
A | VAL90 |
A | HIS97 |
A | ARG101 |
A | PHE108 |
A | ILE236 |
A | ALA239 |
A | GLY240 |
A | THR243 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue EFO A 502 |
Chain | Residue |
A | PHE40 |
A | MET69 |
A | THR71 |
A | MET76 |
A | MET85 |
A | TRP178 |
A | THR288 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGIHHCLG |
Chain | Residue | Details |
A | PHE346-GLY355 | |