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4WLS

Crystal structure of the metal-free (repressor) form of E. Coli CUER, a copper efflux regulator, bound to COPA promoter DNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0000987molecular_functioncis-regulatory region sequence-specific DNA binding
A0001216molecular_functionDNA-binding transcription activator activity
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005507molecular_functioncopper ion binding
A0005737cellular_componentcytoplasm
A0006351biological_processDNA-templated transcription
A0006355biological_processregulation of DNA-templated transcription
A0032993cellular_componentprotein-DNA complex
A0042802molecular_functionidentical protein binding
A0045893biological_processpositive regulation of DNA-templated transcription
A0046872molecular_functionmetal ion binding
B0000976molecular_functiontranscription cis-regulatory region binding
B0000987molecular_functioncis-regulatory region sequence-specific DNA binding
B0001216molecular_functionDNA-binding transcription activator activity
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0005507molecular_functioncopper ion binding
B0005737cellular_componentcytoplasm
B0006351biological_processDNA-templated transcription
B0006355biological_processregulation of DNA-templated transcription
B0032993cellular_componentprotein-DNA complex
B0042802molecular_functionidentical protein binding
B0045893biological_processpositive regulation of DNA-templated transcription
B0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS00552
Number of Residues23
DetailsHTH_MERR_1 MerR-type HTH domain signature. SdVAkiTGLTskaIRfYEek.GLV
ChainResidueDetails
ASER4-VAL26

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues38
DetailsDNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00254
ChainResidueDetails
ASER4-LYS23
BSER4-LYS23

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING:
ChainResidueDetails
ASER112
ASER120
BSER112
BSER120

218853

PDB entries from 2024-04-24

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