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4WHO

Resting Protocatechuate 3,4-dioxygenase (pseudomonas putida) at pH 8.5

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0005506molecular_functioniron ion binding
A0006725biological_processobsolete cellular aromatic compound metabolic process
A0008199molecular_functionferric iron binding
A0016702molecular_functionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A0018578molecular_functionprotocatechuate 3,4-dioxygenase activity
A0019439biological_processobsolete aromatic compound catabolic process
A0042952biological_processbeta-ketoadipate pathway
A0051213molecular_functiondioxygenase activity
B0003824molecular_functioncatalytic activity
B0005506molecular_functioniron ion binding
B0006725biological_processobsolete cellular aromatic compound metabolic process
B0008199molecular_functionferric iron binding
B0016702molecular_functionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B0018578molecular_functionprotocatechuate 3,4-dioxygenase activity
B0019439biological_processobsolete aromatic compound catabolic process
B0019619biological_process3,4-dihydroxybenzoate catabolic process
B0042952biological_processbeta-ketoadipate pathway
B0046872molecular_functionmetal ion binding
B0051213molecular_functiondioxygenase activity
C0003824molecular_functioncatalytic activity
C0005506molecular_functioniron ion binding
C0006725biological_processobsolete cellular aromatic compound metabolic process
C0008199molecular_functionferric iron binding
C0016702molecular_functionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
C0018578molecular_functionprotocatechuate 3,4-dioxygenase activity
C0019439biological_processobsolete aromatic compound catabolic process
C0042952biological_processbeta-ketoadipate pathway
C0051213molecular_functiondioxygenase activity
D0003824molecular_functioncatalytic activity
D0005506molecular_functioniron ion binding
D0006725biological_processobsolete cellular aromatic compound metabolic process
D0008199molecular_functionferric iron binding
D0016702molecular_functionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D0018578molecular_functionprotocatechuate 3,4-dioxygenase activity
D0019439biological_processobsolete aromatic compound catabolic process
D0019619biological_process3,4-dihydroxybenzoate catabolic process
D0042952biological_processbeta-ketoadipate pathway
D0046872molecular_functionmetal ion binding
D0051213molecular_functiondioxygenase activity
E0003824molecular_functioncatalytic activity
E0005506molecular_functioniron ion binding
E0006725biological_processobsolete cellular aromatic compound metabolic process
E0008199molecular_functionferric iron binding
E0016702molecular_functionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
E0018578molecular_functionprotocatechuate 3,4-dioxygenase activity
E0019439biological_processobsolete aromatic compound catabolic process
E0042952biological_processbeta-ketoadipate pathway
E0051213molecular_functiondioxygenase activity
F0003824molecular_functioncatalytic activity
F0005506molecular_functioniron ion binding
F0006725biological_processobsolete cellular aromatic compound metabolic process
F0008199molecular_functionferric iron binding
F0016702molecular_functionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
F0018578molecular_functionprotocatechuate 3,4-dioxygenase activity
F0019439biological_processobsolete aromatic compound catabolic process
F0019619biological_process3,4-dihydroxybenzoate catabolic process
F0042952biological_processbeta-ketoadipate pathway
F0046872molecular_functionmetal ion binding
F0051213molecular_functiondioxygenase activity
Functional Information from PDB Data
site_idAC1
Number of Residues3
Detailsbinding site for residue BCT A 301
ChainResidue
AASN37
ATHR105
AHIS107

site_idAC2
Number of Residues5
Detailsbinding site for residue FE B 601
ChainResidue
BTYR408
BTYR447
BHIS460
BHIS462
BHOH868

site_idAC3
Number of Residues4
Detailsbinding site for residue BME B 602
ChainResidue
AHOH519
BTYR324
BTHR326
APRO15

site_idAC4
Number of Residues5
Detailsbinding site for residue FE D 600
ChainResidue
DTYR408
DTYR447
DHIS460
DHIS462
DHOH889

site_idAC5
Number of Residues5
Detailsbinding site for residue BME F 601
ChainResidue
EPRO15
EARG133
FTYR324
FTHR326
FTRP449

site_idAC6
Number of Residues5
Detailsbinding site for residue FE F 602
ChainResidue
FTYR408
FTYR447
FHIS460
FHIS462
FHOH859

Functional Information from PROSITE/UniProt
site_idPS00083
Number of Residues29
DetailsINTRADIOL_DIOXYGENAS Intradiol ring-cleavage dioxygenases signature. LlGqVydgnGhlVrdsfLEVwqadanGeY
ChainResidueDetails
ALEU51-TYR79
BVAL380-TYR408
DVAL380-TYR408

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:7990141
ChainResidueDetails
DTYR408
DTYR447
DHIS460
DHIS462
FTYR408
FTYR447
FHIS460
FHIS462

Catalytic Information from CSA
site_idMCSA1
Number of Residues5
DetailsM-CSA 936
ChainResidueDetails
DTYR408metal ligand
DTYR447metal ligand, proton shuttle (general acid/base)
DARG457electrostatic stabiliser
DHIS460metal ligand
DHIS462metal ligand

site_idMCSA2
Number of Residues5
DetailsM-CSA 936
ChainResidueDetails
FTYR408metal ligand
FTYR447metal ligand, proton shuttle (general acid/base)
FARG457electrostatic stabiliser
FHIS460metal ligand
FHIS462metal ligand

219140

PDB entries from 2024-05-01

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