4V0N
Crystal structure of BBS1N in complex with ARL6DN, soaked with mercury
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005930 | cellular_component | axoneme |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0060271 | biological_process | cilium assembly |
| A | 0061512 | biological_process | protein localization to cilium |
| B | 0034464 | cellular_component | BBSome |
| B | 1905515 | biological_process | non-motile cilium assembly |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005930 | cellular_component | axoneme |
| C | 0006886 | biological_process | intracellular protein transport |
| C | 0016192 | biological_process | vesicle-mediated transport |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0060271 | biological_process | cilium assembly |
| C | 0061512 | biological_process | protein localization to cilium |
| D | 0034464 | cellular_component | BBSome |
| D | 1905515 | biological_process | non-motile cilium assembly |
| E | 0003924 | molecular_function | GTPase activity |
| E | 0005525 | molecular_function | GTP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005930 | cellular_component | axoneme |
| E | 0006886 | biological_process | intracellular protein transport |
| E | 0016192 | biological_process | vesicle-mediated transport |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0060271 | biological_process | cilium assembly |
| E | 0061512 | biological_process | protein localization to cilium |
| F | 0034464 | cellular_component | BBSome |
| F | 1905515 | biological_process | non-motile cilium assembly |
| G | 0003924 | molecular_function | GTPase activity |
| G | 0005525 | molecular_function | GTP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005930 | cellular_component | axoneme |
| G | 0006886 | biological_process | intracellular protein transport |
| G | 0016192 | biological_process | vesicle-mediated transport |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0060271 | biological_process | cilium assembly |
| G | 0061512 | biological_process | protein localization to cilium |
| H | 0034464 | cellular_component | BBSome |
| H | 1905515 | biological_process | non-motile cilium assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GTP A 600 |
| Chain | Residue |
| A | ASP26 |
| A | SER71 |
| A | GLY72 |
| A | ASN128 |
| A | LYS129 |
| A | ASP131 |
| A | ASN161 |
| A | GLY162 |
| A | LEU163 |
| A | MG601 |
| A | ASN27 |
| A | SER28 |
| A | GLY29 |
| A | LYS30 |
| A | THR31 |
| A | THR32 |
| A | ALA48 |
| A | THR50 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | THR31 |
| A | THR50 |
| A | GTP600 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE GTP C 600 |
| Chain | Residue |
| C | ASN27 |
| C | SER28 |
| C | GLY29 |
| C | LYS30 |
| C | THR31 |
| C | THR32 |
| C | THR50 |
| C | SER71 |
| C | GLY72 |
| C | ASN128 |
| C | LYS129 |
| C | ASP131 |
| C | LEU132 |
| C | ASN161 |
| C | GLY162 |
| C | MG601 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 601 |
| Chain | Residue |
| C | THR31 |
| C | THR50 |
| C | ASP69 |
| C | MET70 |
| C | GTP600 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTP E 600 |
| Chain | Residue |
| E | ASN27 |
| E | SER28 |
| E | GLY29 |
| E | LYS30 |
| E | THR31 |
| E | THR32 |
| E | PRO49 |
| E | THR50 |
| E | SER71 |
| E | GLY72 |
| E | ASN128 |
| E | LYS129 |
| E | ASP131 |
| E | ASN161 |
| E | GLY162 |
| E | LEU163 |
| E | MG601 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG E 601 |
| Chain | Residue |
| E | LYS30 |
| E | THR31 |
| E | THR50 |
| E | ASP69 |
| E | GTP600 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GTP G 600 |
| Chain | Residue |
| G | ASN27 |
| G | SER28 |
| G | GLY29 |
| G | LYS30 |
| G | THR31 |
| G | THR32 |
| G | ALA48 |
| G | THR50 |
| G | SER71 |
| G | GLY72 |
| G | ASN128 |
| G | LYS129 |
| G | ASP131 |
| G | ASN161 |
| G | GLY162 |
| G | LEU163 |
| G | MG601 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG G 601 |
| Chain | Residue |
| G | THR31 |
| G | THR50 |
| G | GTP600 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG B 1426 |
| Chain | Residue |
| B | VAL99 |
| B | ALA100 |
| B | THR217 |
| B | CYS218 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG B 1427 |
| Chain | Residue |
| B | CYS57 |
| B | VAL99 |
| B | HG1438 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG H 1426 |
| Chain | Residue |
| H | CYS57 |
| H | VAL99 |
| H | HG1433 |
| H | HG1437 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HG H 1427 |
| Chain | Residue |
| H | HG1438 |
| H | HG1439 |
| H | THR217 |
| H | CYS218 |
| H | ALA265 |
| H | MET266 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG B 1428 |
| Chain | Residue |
| B | LEU303 |
| B | CYS321 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG B 1429 |
| Chain | Residue |
| B | ILE101 |
| B | CYS102 |
| B | ASP220 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG H 1428 |
| Chain | Residue |
| H | CYS234 |
| H | LEU247 |
| H | PRO249 |
| H | HG1432 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG H 1429 |
| Chain | Residue |
| H | LEU303 |
| H | ALA305 |
| H | GLN306 |
| H | CYS321 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG B 1430 |
| Chain | Residue |
| B | CYS234 |
| B | LEU247 |
| B | HG1433 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG H 1430 |
| Chain | Residue |
| H | CYS102 |
| H | ASP220 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG D 1426 |
| Chain | Residue |
| D | LEU303 |
| D | GLN306 |
| D | CYS321 |
| D | HG1432 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HG F 1426 |
| Chain | Residue |
| F | LEU303 |
| F | ALA305 |
| F | GLN306 |
| F | CYS321 |
| F | HG1432 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HG H 1431 |
| Chain | Residue |
| H | CYS61 |
| H | ASN62 |
| H | SER103 |
| H | PRO114 |
| H | HG1435 |
| H | HG1436 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG D 1427 |
| Chain | Residue |
| D | THR217 |
| D | CYS218 |
| D | ALA265 |
| D | MET266 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HG F 1427 |
| Chain | Residue |
| F | THR217 |
| F | CYS218 |
| F | ALA265 |
| F | MET266 |
| F | HG1438 |
| F | HG1439 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG B 1431 |
| Chain | Residue |
| B | CYS61 |
| B | SER103 |
| B | PRO114 |
| B | HG1434 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HG F 1428 |
| Chain | Residue |
| F | HIS59 |
| F | ILE101 |
| F | CYS102 |
| F | MET219 |
| F | ASP220 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG D 1428 |
| Chain | Residue |
| D | CYS102 |
| D | ASP220 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG D 1429 |
| Chain | Residue |
| D | CYS57 |
| D | VAL99 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG F 1429 |
| Chain | Residue |
| F | CYS57 |
| F | VAL99 |
| F | HG1435 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG F 1430 |
| Chain | Residue |
| F | CYS61 |
| F | SER103 |
| F | HG1436 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG D 1430 |
| Chain | Residue |
| D | CYS61 |
| D | SER103 |
| D | HG1434 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG E 1181 |
| Chain | Residue |
| E | HIS111 |
| E | LYS114 |
| F | THR421 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HG D 1431 |
| Chain | Residue |
| D | CYS234 |
| D | LEU247 |
| D | ASN248 |
| D | PRO249 |
| D | HG1435 |
| D | HG1437 |
| site_id | DC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE HG C 1181 |
| Chain | Residue |
| C | HIS111 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG F 1431 |
| Chain | Residue |
| F | CYS234 |
| F | HG1433 |
| F | HG1434 |
| F | HG1437 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG G 1181 |
| Chain | Residue |
| G | HIS111 |
| H | THR421 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG A 1181 |
| Chain | Residue |
| A | HIS111 |
| A | LYS114 |
| B | THR421 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG B 1432 |
| Chain | Residue |
| B | GLN224 |
| B | VAL232 |
| site_id | EC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG B 1433 |
| Chain | Residue |
| B | LEU247 |
| B | HG1430 |
| site_id | EC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG H 1432 |
| Chain | Residue |
| H | LEU247 |
| H | HG1428 |
| site_id | EC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG H 1433 |
| Chain | Residue |
| H | CYS57 |
| H | ALA74 |
| H | HG1426 |
| site_id | EC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG H 1434 |
| Chain | Residue |
| H | GLN224 |
| H | VAL232 |
| H | PRO249 |
| site_id | EC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG D 1432 |
| Chain | Residue |
| D | LEU303 |
| D | PRO307 |
| D | HG1426 |
| site_id | EC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG H 1435 |
| Chain | Residue |
| H | CYS61 |
| H | ASN62 |
| H | ASN69 |
| H | HG1431 |
| site_id | EC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG F 1432 |
| Chain | Residue |
| F | GLY286 |
| F | LEU303 |
| F | HG1426 |
| site_id | EC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG H 1436 |
| Chain | Residue |
| H | SER103 |
| H | HG1431 |
| site_id | FC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG B 1434 |
| Chain | Residue |
| B | SER103 |
| B | HG1431 |
| site_id | FC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG H 1437 |
| Chain | Residue |
| H | PRO56 |
| H | VAL99 |
| H | HG1426 |
| site_id | FC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG B 1435 |
| Chain | Residue |
| B | CYS61 |
| B | LEU63 |
| B | SER103 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG F 1433 |
| Chain | Residue |
| F | LEU247 |
| F | VAL255 |
| F | HG1431 |
| F | HG1437 |
| site_id | FC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG F 1434 |
| Chain | Residue |
| F | GLN224 |
| F | LEU273 |
| F | HG1431 |
| site_id | FC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG H 1438 |
| Chain | Residue |
| H | THR217 |
| H | CYS218 |
| H | HG1427 |
| site_id | FC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HG H 1439 |
| Chain | Residue |
| H | THR217 |
| H | CYS218 |
| H | PRO264 |
| H | MET266 |
| H | ILE267 |
| H | HG1427 |
| site_id | FC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG F 1435 |
| Chain | Residue |
| F | ALA53 |
| F | TYR54 |
| F | CYS57 |
| F | HG1429 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG D 1433 |
| Chain | Residue |
| D | CYS57 |
| D | ALA74 |
| D | PRO98 |
| site_id | GC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG D 1434 |
| Chain | Residue |
| D | CYS61 |
| D | ASN62 |
| D | HG1430 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HG D 1435 |
| Chain | Residue |
| D | ILE246 |
| D | LEU247 |
| D | VAL255 |
| D | HG1431 |
| D | HG1437 |
| site_id | GC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG F 1436 |
| Chain | Residue |
| F | CYS61 |
| F | ASN62 |
| F | HG1430 |
| site_id | GC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE HG F 1437 |
| Chain | Residue |
| F | CYS234 |
| F | LEU247 |
| F | ASN248 |
| F | PRO249 |
| F | HG1431 |
| F | HG1433 |
| site_id | GC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HG D 1436 |
| Chain | Residue |
| D | LYS223 |
| D | GLN224 |
| D | CYS234 |
| D | LEU273 |
| D | HG1437 |
| site_id | GC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG F 1438 |
| Chain | Residue |
| F | THR217 |
| F | CYS218 |
| F | PRO264 |
| F | HG1427 |
| site_id | GC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG B 1436 |
| Chain | Residue |
| B | THR217 |
| B | CYS218 |
| B | ALA265 |
| site_id | GC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG D 1437 |
| Chain | Residue |
| D | CYS234 |
| D | HG1431 |
| D | HG1435 |
| D | HG1436 |
| site_id | GC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HG B 1437 |
| Chain | Residue |
| B | CYS321 |
| B | VAL325 |
| B | VAL326 |
| B | HIS327 |
| site_id | HC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG F 1439 |
| Chain | Residue |
| F | CYS218 |
| F | ALA265 |
| F | HG1427 |
| site_id | HC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HG B 1438 |
| Chain | Residue |
| B | PRO56 |
| B | VAL99 |
| B | HG1427 |
