4UFM
Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004336 | molecular_function | galactosylceramidase activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005764 | cellular_component | lysosome |
| A | 0006665 | biological_process | sphingolipid metabolic process |
| A | 0006683 | biological_process | galactosylceramide catabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0042552 | biological_process | myelination |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000269|PubMed:21876145 |
| Chain | Residue | Details |
| A | GLU182 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:21876145 |
| Chain | Residue | Details |
| A | GLU258 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | THR93 | |
| A | TRP135 | |
| A | ASN181 | |
| A | ARG380 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21876145 |
| Chain | Residue | Details |
| A | ASN284 | |
| A | ASN363 | |
| A | ASN387 | |
| A | ASN542 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN585 | |
| A | ASN629 |
