Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4RXF

Fructose-6-phosphate aldolase Y131F from E.coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006000	biological_process	fructose metabolic process
A	0016829	molecular_function	lyase activity
A	0016832	molecular_function	aldehyde-lyase activity
A	0042182	biological_process	ketone catabolic process
A	0042802	molecular_function	identical protein binding
A	0097023	molecular_function	fructose 6-phosphate aldolase activity
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0006000	biological_process	fructose metabolic process
B	0016829	molecular_function	lyase activity
B	0016832	molecular_function	aldehyde-lyase activity
B	0042182	biological_process	ketone catabolic process
B	0042802	molecular_function	identical protein binding
B	0097023	molecular_function	fructose 6-phosphate aldolase activity
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0006000	biological_process	fructose metabolic process
C	0016829	molecular_function	lyase activity
C	0016832	molecular_function	aldehyde-lyase activity
C	0042182	biological_process	ketone catabolic process
C	0042802	molecular_function	identical protein binding
C	0097023	molecular_function	fructose 6-phosphate aldolase activity
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0006000	biological_process	fructose metabolic process
D	0016829	molecular_function	lyase activity
D	0016832	molecular_function	aldehyde-lyase activity
D	0042182	biological_process	ketone catabolic process
D	0042802	molecular_function	identical protein binding
D	0097023	molecular_function	fructose 6-phosphate aldolase activity
E	0005737	cellular_component	cytoplasm
E	0005975	biological_process	carbohydrate metabolic process
E	0006000	biological_process	fructose metabolic process
E	0016829	molecular_function	lyase activity
E	0016832	molecular_function	aldehyde-lyase activity
E	0042182	biological_process	ketone catabolic process
E	0042802	molecular_function	identical protein binding
E	0097023	molecular_function	fructose 6-phosphate aldolase activity
F	0005737	cellular_component	cytoplasm
F	0005975	biological_process	carbohydrate metabolic process
F	0006000	biological_process	fructose metabolic process
F	0016829	molecular_function	lyase activity
F	0016832	molecular_function	aldehyde-lyase activity
F	0042182	biological_process	ketone catabolic process
F	0042802	molecular_function	identical protein binding
F	0097023	molecular_function	fructose 6-phosphate aldolase activity
G	0005737	cellular_component	cytoplasm
G	0005975	biological_process	carbohydrate metabolic process
G	0006000	biological_process	fructose metabolic process
G	0016829	molecular_function	lyase activity
G	0016832	molecular_function	aldehyde-lyase activity
G	0042182	biological_process	ketone catabolic process
G	0042802	molecular_function	identical protein binding
G	0097023	molecular_function	fructose 6-phosphate aldolase activity
H	0005737	cellular_component	cytoplasm
H	0005975	biological_process	carbohydrate metabolic process
H	0006000	biological_process	fructose metabolic process
H	0016829	molecular_function	lyase activity
H	0016832	molecular_function	aldehyde-lyase activity
H	0042182	biological_process	ketone catabolic process
H	0042802	molecular_function	identical protein binding
H	0097023	molecular_function	fructose 6-phosphate aldolase activity
I	0005737	cellular_component	cytoplasm
I	0005975	biological_process	carbohydrate metabolic process
I	0006000	biological_process	fructose metabolic process
I	0016829	molecular_function	lyase activity
I	0016832	molecular_function	aldehyde-lyase activity
I	0042182	biological_process	ketone catabolic process
I	0042802	molecular_function	identical protein binding
I	0097023	molecular_function	fructose 6-phosphate aldolase activity
J	0005737	cellular_component	cytoplasm
J	0005975	biological_process	carbohydrate metabolic process
J	0006000	biological_process	fructose metabolic process
J	0016829	molecular_function	lyase activity
J	0016832	molecular_function	aldehyde-lyase activity
J	0042182	biological_process	ketone catabolic process
J	0042802	molecular_function	identical protein binding
J	0097023	molecular_function	fructose 6-phosphate aldolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 A 301

Chain	Residue
A	ARG134
A	LYS168
A	HOH420

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 B 301

Chain	Residue
B	ARG134
B	LYS168
C	LYS206

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 C 301

Chain	Residue
C	ARG134
C	LYS168

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 D 301

Chain	Residue
D	LYS168
D	HOH419
E	LYS206
D	ARG134

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 E 301

Chain	Residue
A	LYS206
E	ARG134
E	LYS168

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 F 301

Chain	Residue
F	ARG134
F	LYS168
J	LYS206

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 G 301

Chain	Residue
G	ARG134
G	LYS168

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 H 301

Chain	Residue
H	ARG134
H	LYS168

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 I 301

Chain	Residue
I	ARG134
I	LYS168

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PO4 J 301

Chain	Residue
J	ARG134
J	LYS168

Functional Information from PROSITE/UniProt

site_id	PS00958
Number of Residues	18
Details	TRANSALDOLASE_2 Transaldolase active site. IvVKVPvTaEGLaAiKmL

Chain	Residue	Details
A	ILE82-LEU99

site_id	PS01054
Number of Residues	9
Details	TRANSALDOLASE_1 Transaldolase signature 1. GVTTNPSII

Chain	Residue	Details
A	GLY24-ILE32

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	ACT_SITE: Schiff-base intermediate with substrate => ECO:0000269\|PubMed:11120740, ECO:0000269\|PubMed:12051943

Chain	Residue	Details
A	LYS85
B	LYS85
C	LYS85
D	LYS85
E	LYS85
F	LYS85
G	LYS85
H	LYS85
I	LYS85
J	LYS85

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)