4RIZ

The crystal structure of Y333Q mutant pyridoxal-dependent decarboxylase from Sphaerobacter thermophilus dsm 20745

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004782	molecular_function	sulfinoalanine decarboxylase activity
A	0005737	cellular_component	cytoplasm
A	0016829	molecular_function	lyase activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0030170	molecular_function	pyridoxal phosphate binding
B	0004782	molecular_function	sulfinoalanine decarboxylase activity
B	0005737	cellular_component	cytoplasm
B	0016829	molecular_function	lyase activity
B	0016830	molecular_function	carbon-carbon lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0030170	molecular_function	pyridoxal phosphate binding
C	0004782	molecular_function	sulfinoalanine decarboxylase activity
C	0005737	cellular_component	cytoplasm
C	0016829	molecular_function	lyase activity
C	0016830	molecular_function	carbon-carbon lyase activity
C	0016831	molecular_function	carboxy-lyase activity
C	0019752	biological_process	carboxylic acid metabolic process
C	0030170	molecular_function	pyridoxal phosphate binding
D	0004782	molecular_function	sulfinoalanine decarboxylase activity
D	0005737	cellular_component	cytoplasm
D	0016829	molecular_function	lyase activity
D	0016830	molecular_function	carbon-carbon lyase activity
D	0016831	molecular_function	carboxy-lyase activity
D	0019752	biological_process	carboxylic acid metabolic process
D	0030170	molecular_function	pyridoxal phosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PMP A 501

Chain	Residue
A	GLY150
A	GLN303
A	LLP304
A	HOH620
A	HOH741
A	HOH841
B	THR351
A	GLY151
A	SER152
A	HIS190
A	GLY245
A	THR247
A	ASP272
A	ALA274
A	ASN301

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 502

Chain	Residue
A	HIS353
A	HOH685
A	HOH686
B	HIS353
B	HOH629

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 501

Chain	Residue
B	LEU136
B	PHE137
B	ARG286
B	GLU293

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL B 503

Chain	Residue
B	LEU374
B	ASP377
B	GLY378
B	LEU381
B	LEU454
B	LEU455
B	ASN456
B	PRO457
B	HOH648

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA B 504

Chain	Residue
A	GLU171
A	PRO172
B	ARG180
B	LEU202
B	GLY203
B	ALA205
B	ALA206

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site_id	AC6
Number of Residues	13
Details	BINDING SITE FOR RESIDUE PMP C 2001

Chain	Residue
C	GLY150
C	GLY151
C	SER152
C	HIS190
C	THR247
C	ASP272
C	ALA274
C	ASN301
C	GLN303
C	LLP304
C	HOH2217
C	HOH2261
D	THR351

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site_id	AC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PMP D 501

Chain	Residue
C	THR351
C	HOH2127
D	GLY150
D	GLY151
D	SER152
D	HIS190
D	GLY245
D	THR247
D	ASP272
D	ALA274
D	ASN301
D	GLN303
D	LLP304
D	HOH694

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 502

Chain	Residue
D	LEU136
D	ARG286
D	ALA290
D	GLU293

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site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA D 503

Chain	Residue
C	GLU171
C	PRO172
D	ARG180
D	LEU202
D	GLY203
D	ALA205
D	ALA206

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