4QU4

Improved refinement of the Mtr4 apo crystal structure

Replaces:  3L9O

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000292	biological_process	RNA fragment catabolic process
A	0000460	biological_process	maturation of 5.8S rRNA
A	0000467	biological_process	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0003729	molecular_function	mRNA binding
A	0003824	molecular_function	catalytic activity
A	0004386	molecular_function	helicase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005730	cellular_component	nucleolus
A	0006364	biological_process	rRNA processing
A	0006397	biological_process	mRNA processing
A	0006401	biological_process	RNA catabolic process
A	0008143	molecular_function	poly(A) binding
A	0016075	biological_process	rRNA catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0031499	cellular_component	TRAMP complex
A	0034458	molecular_function	3'-5' RNA helicase activity
A	0034475	biological_process	U4 snRNA 3'-end processing
A	0034476	biological_process	U5 snRNA 3'-end processing
A	0071028	biological_process	nuclear mRNA surveillance
A	0071031	biological_process	nuclear mRNA surveillance of mRNA 3'-end processing
A	0071035	biological_process	nuclear polyadenylation-dependent rRNA catabolic process
A	0071038	biological_process	TRAMP-dependent tRNA surveillance pathway
A	0071042	biological_process	nuclear polyadenylation-dependent mRNA catabolic process
A	0071051	biological_process	poly(A)-dependent snoRNA 3'-end processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 A 1101

Chain	Residue
A	GLU263
A	TYR266
A	GLY508

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 A 1102

Chain	Residue
A	LYS416
A	HIS476
A	SER477
A	THR502
A	THR504

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PO4 A 1103

Chain	Residue
A	LYS827

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541

Chain	Residue	Details
A	ALA171

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17287358

Chain	Residue	Details
A	THR34

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	SER84

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
A	SER843

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